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Vaccine Effective Against Avian Flu

FiReaNGeL writes "Researchers announced they have genetically engineered an avian flu vaccine from the critical components of the deadly H5N1 virus that completely protected mice and chickens from infection. This virus has thus far killed 80 people, devastated bird populations in Southeast Asia and Europe and caused for billions in damage through the world." Here's hoping it works on us, too.

6 of 44 comments (clear)

  1. Re:yet another drug that will be overused by exi1ed0ne · · Score: 3, Interesting

    In the dusty recesses of my memory, I seem to recall some experimentation where they sprayed benign bacteria on chickens. The theory goes that the competition for resources and the ample supply of non-harmful bacteria would reduce the sustainable population of harmful bacteria.

    I find it interesting that being too clean of all bacteria can actually have harmful effects. We're really colony organisms after all. I wondered whatever happened with it?

    --
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  2. 1918 Flu was Bird Flu by DigitalRaptor · · Score: 3, Interesting

    Recently researchers were able to recreate the 1918 flu that killed 100 million around the world, and what they found was a little alarming. The 1918 flu jumped directly from birds to humans and became transmissable between humans.

    If the current bird flu manages that, there will be an 18 month siege on the economy the likes of which our generations have never seen as borders are shut down and vital supply chains are broken.

    Hopefully this new advance offers some hope. Who knows if a pandemic will happen (well, one will happen without a doubt because they have on average every 30 years for the last 300, but we just don't know if this bird flu is the next one), it's just a roll of the dice everytime a human gets infected whether it will mutate.

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    1. Re:1918 Flu was Bird Flu by DigitalRaptor · · Score: 3, Insightful

      The problem is, what happens when the power goes out because everyone who works at the powerplant is dead, infected, taking care of sick family, or unable / unwilling to come to work?

      Same with the ISP, the hospital (which has no medicine anyway), the grocery store (which has no food anyway), the gas station (which has no gas or goodies to sell anyway).

      People don't realize how much our society relies on JIT, Just In Time delivery. Most stores have less than a week of food on hand and it is constantly replenished. Most gas stations have less than a week of gas onhand. Most hospitals have less than a few weeks medicine on hand.

      If the bird flu becomes human to human transmissible, it won't be pretty, and we won't be sitting at home surfing the `net with a Starbucks. Hopefully we'll have food, water, and electricity.

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  3. Re:Virus Fund, let's do it. by XenoRyet · · Score: 3, Insightful
    Only 80 deaths. That is not statisticaly signifigant in any size population.

    Not only do we not need an Avian Flu specific fund, the money already dedicated to the purpose was too much. There are litteraly thousands of more deadly illnesses out there, currently active, and currently transmitible between humans. Why should we spend billions on this one virus that has thus for only shown the potential for danger?

    The first world nations don't need to pledge to do anything on this yet. There is nothing to do yet, Avian influenza is not a threat, it only has potential to become a threat. It would be almost criminal to spend so much on a thus-far fairly begnine virus. First world nations need to have a little perspective before dedicating billions to the media's current favorite "crisis".

    No, I think the normal reaserch budgets will be more than sufficent to look into Avian Flu for the moment. Those extra billions would be much better spent in a miriad of other places.

    --
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  4. Re:Why are we talking about Avian Flu by MtlDty · · Score: 3, Insightful

    Avian flu is now endemic amongst birds in South Asia, and was reportedly suspected to be endemic amongst birds in Turkey (which I still find bitterly ironic)

    It may have only killed 80 people so far, but thats over 50% of the 150 or so people that have been infected. If the mortality rate is as severe when the virus mutates into a form more transmitable between humans then we're in real trouble - estimates of 150,000,000 deaths worldwide would ensure that someone you know personally will die.

    There arent many professionals in the field that believe we can escape an imminent birdflu pandemic. So, in short, yes - it is likely that this will turn into a pandemic and we should all be as prepared as possible for that.

  5. Re:Virus Fund, let's do it. by (negative+video) · · Score: 5, Interesting
    Only 80 deaths. That is not statisticaly signifigant in any size population.
    The significance is that the manner of death was wholly unexpected. Young, strong people virtually never die from sudden lung inflammation. Tuberculosis, yes. Bacterial pneumonia, yes. But their own immune system just suddenly deciding to burn their lungs to the ground? Never happens.
    There are litteraly thousands of more deadly illnesses out there, currently active, and currently transmitible between humans.
    True, but most of them are either difficult to transmit (HIV, hepatitis A, rabies), are virulent and have obvious symptoms so that quarantine can be effective (ebola), or produce lasting immunity (bacterial meningitis, cholera).

    Influenza, however, combines most of the worst things into a single virus. It is an RNA virus, so it mutates rapidly. It has a tiny genome, providing a minimal target for the adaptive immune system. It spreads easily through the air, allowing less-ill carriers to spread it widely (the Tyhoid Mary effect). It starts out by pretending to be the common cold, so carriers ignore it and continue to expose the community. Very few disease organisms combine these factors, and most of those that do (measles, smallpox, diptheria) are mercifully vulnerable to vaccines.

    Why should we spend billions on this one virus that has thus for only shown the potential for danger?
    Because the potential is real and quantified, not blindy extrapolated from fears. Influenza does regularly sweep across the world, leaving death and destruction in its wake. It does regularly kill people even in wealthy countries. The 1918 pandemic did send millions of strong, healthy adults to their deaths.

    Certain strains are right now killing strong, healthy adults. Certain other strains do right now have the molecular factors for extreme transmissibility. It is an absolute guarantee that those strains will fuse in a single infected person, producing a new strain that has both virulence and transmissibility. When that happens, we will have another 1918-style pandemic on our hands.

    And unless we can rapidly turn-around production of a strong vaccine, that pandemic will strike down millions of us. On the basis of missed work days alone, it makes sense to pour billions of dollars into preventing a flu pandemic.