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Using Liquid Crystals to Guide Stem Cells

An anonymous reader writes "Liquid crystals, the same phase-shifting materials used to display information on cell phones, monitors and other electronic equipment, can also be used to control the differentiation of embryonic stem cells, Wisconsin researchers say. By using the crystals to mechanically strain the cells, they can prevent the indiscriminate (and unwanted) differentiation common in embryonic stem cell research and therapy. So when you want a bone cell, say, you don't end up with one from the kidney."

22 of 104 comments (clear)

  1. Science? by Anonymous Coward · · Score: 5, Funny

    Sounds more like black voodoo magic wizardry to me. If God wants it to be a bone cell, they by His name, it will be a bone cell.

    1. Re:Science? by DigiShaman · · Score: 3, Funny

      What? You need God to "bone home"?

      --
      Life is not for the lazy.
    2. Re:Science? by ArcherB · · Score: 3, Funny

      Sounds more like black voodoo magic wizardry to me

      BLACK voodoo magic? Why does it always have to be a black thing with you?

      --
      There is no "I disagree" mod for a reason. Flamebait, Troll, and Overrated are not substitutes.
  2. Lets get this out of they way by geekoid · · Score: 4, Informative

    Embryonic stem cells are stems cells that are going to waste anyways. Left over from in vitro fertilization.
    They are from the from the blastocyst stage,and about 128 cells.

    also:
    http://stemcells.nih.gov/info/scireport/chapter2.a sp

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    1. Re:Lets get this out of they way by Anonymous Coward · · Score: 3, Interesting

      According to the bible, as well as the Catholic Church, the body doesn't begin life until blood flows through it. The body first has blood flowing through at approximately the 40th day, so using these extremely young blastocysts means that the stem cells aren't living people, thus we can't murder them. So we can use them.

    2. Re:Lets get this out of they way by blurn · · Score: 3, Interesting

      I believe the scripture reference you should use to defend your argument can be found in Leviticus 17:11. Be careful, I agree with you, but this verse (coming out of a NIV Bible) should not be streched to say something it is not. If you found anything else, in any Bible, that can prove what you are saying, please post it.

      It is really ironic, the verse I mentioned was quoted on CSI.

    3. Re:Lets get this out of they way by metternich · · Score: 2, Insightful

      You're probably trolling but the second verse refers to transubstantiation. You know when people eat bread and wine during communion? The bread is symbolic for the body of Christ and the wine for his blood. (Or according to some it actually becomes the body and blood of Christ, though not physically.)

      --
      Facts do not cease to exist because they are ignored.
    4. Re:Lets get this out of they way by dancpsu · · Score: 3, Informative

      First Verse in context:

      The LORD said:
      I will turn against any of my people who eat blood. This also includes any foreigners living among you. Life is in the blood, and I have given you the blood of animals to sacrifice in place of your own. That's also why I have forbidden you to eat blood. Even if you should hunt and kill a bird or an animal, you must drain out the blood and cover it with soil.


      It's kind of hard to interpret both what it meant to the ancient Hebrew when it says "I will turn against...". Probably in this context it was something to do with a person will fall to ill health by consuming blood. In the "Life is in the blood" section it goes on to reference the animal sacrifice religious practice of the time. It was important in this tradition to set apart things that were at all unclean, and similarly set apart things that were "holy". The blood here would qualify as being holy all the way back to Abraham when he cut animals in half to enter into a contract with God.

      Second in context:

      Jesus answered:
      I tell you for certain that you won't live unless you eat the flesh and drink the blood of the Son of Man. But if you do eat my flesh and drink my blood, you will have eternal life, and I will raise you to life on the last day. My flesh is the true food, and my blood is the true drink. If you eat my flesh and drink my blood, you are one with me, and I am one with you.


      To put this in a little more context, this was the middle of the Passover Seder, probably the second or third drinks of wine. This is the time where the Jewish people were supposed to remember the redemption of Moses and in particular the Passover Lamb (as in the Ten Commandments movie). Jesus, by placing himself in this section of the ritual was taking the place of the sacrificial animal as mentioned in the first verse. Therefore establishing himself as the sacrifice in place of the animal. (And literally being killed the next day on the cross)

      --
      "Scientists don't change their minds, they just die." -- Max Planck
    5. Re:Lets get this out of they way by Rolgar · · Score: 2, Informative
      Incorrect, according to both Catholic and Eastern Orthodox churches, the host bread and wine becomes the body and blood of Christ spiritually and physically in all regards except in appearance. The distinction that the matter can look like wine and bread and physically be flesh and blood is based upon the philosophical work of the Aristotle.

      God has proven the point on a few occasions, as the appearance has changed as well, and the priest was left holding a piece of flesh in his hand and a chalace of blood with testable DNA on the altar. Some instances of this can be found at http://www.therealpresence.org/eucharst/mir/a3.htm l

  3. what i really want... by Anonymous Coward · · Score: 5, Funny

    ...is to grow a new 19' LCD monitor. can we do that? No? Oh screw Bush and his policies

    1. Re:what i really want... by MobileTatsu-NJG · · Score: 2, Funny

      "...is to grow a new 19' LCD monitor. can we do that? No? Oh screw Bush and his policies"

      What the hell are you going to do with a 19 foot LCD? Sit in front of it and say "Make it so"?

      --

      "I like to lick butts!" by MobileTatsu-NJG (#32700246) (Score:5, Informative)

  4. Building Hearts And Minds by Anonymous Coward · · Score: 3, Insightful

    ..from the cells of new life. (Yes, I believe life begins at fertilization).

    Destroying life to build and enhance ours.

    Sorry, but I don't want to be part of that brave new world.

    1. Re:Building Hearts And Minds by GundamFan · · Score: 3, Insightful

      I do not deny that there are ethical issues here. I also think condeming others to death by supressing or crippling scientific advancment is wrong. As wrong as using this reaserch for anything other than life saving purposes. Long and short: your views are valid but you have no right to force them on others or make those who bleave diffrent things sound like monsters. If you don't want to be a part of the "brave new world" then don't.

      --
      I don't give a damn for a man that can only spell a word one way.
      Mark Twain
    2. Re:Building Hearts And Minds by TubeSteak · · Score: 2, Insightful

      At least he was referencing some source to back up his facts.

      An unfortunate number of Jesus lovers can't quote relevant sections of the New/Old Testament to support their positions. They just take it on faith that the Bible supports their position.

      You can't argue with someone who hasn't put any thought into their positions. Someone who has read background material, will hopefully have thought about what they've read.

      I know "you must be new here" because people RTFA all the time and make ignorant statements, but at least you can point to TFA and say: See, here's why you're wrong.

      --
      [Fuck Beta]
      o0t!
  5. And what's so wrong... by jd · · Score: 2, Funny

    ...with having a spare kidney growing instead of a stomach cell? If it works, it'll help make NHS food edible. If it doesn't, it'll replace the NHS food altogether.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  6. technology crossovers are funny by mrpeebles · · Score: 3, Interesting

    Makes you wonder if 100 years from now, after display technology has moved on to God-knows-what, people think LC technology primarily as some sort of biotechnology, sort of like we think of the radar device in our microwave as being primarily a cooking device, or the mirror as a safety device in cars. Then the moment is over, and you post whatever your view is on the personhood of embryonic stem cells.

  7. "That's strange." by RoffleTheWaffle · · Score: 2, Funny

    "I could've sworn I was going to have my bone tissues replaced, but somehow my femur feels a lot like a kidney today..."

  8. Not always... by Upaut · · Score: 3, Interesting

    From in vitro fertilization. You can also get these cells from theraputic cloning. Take a good cloning cell (hair folicle or gut work best. Basically cells that divide most often into themselves.), take an egg cell (Or, if your really good, some studies have shown you can get adult stem cells to become a reproductive cell. Though that technology is a bit far behind to work for this example. Ten years from now -or a week, can never tell when an advancement like that will be made- then you could get as many egg cells from your own body, regardless of sex, and for a lot less pain of finding a donor and injecting her with a shitload of hormones, then plunging a harvesting needle into her abdomen... And it would be a "true" clone, with the mitotic DNA being the same.) Make a slit in egg, remove nucleus. Make a slit in donor cell, remove nucleus. Put donor nucleus in egg cell. Apply a small shock to promote healing and division. Wait a few days. Now you have perfect embrionic stem cells that are a match to your own DNA. Do this a few times to ensure you get at least one healthy sample.

    Now you can take these cells, and make new neural tissue, for treating diseases like parkinsons. Or fit into a mold for a new bladder (they managed to make this in dogs), or use the technology of the bladder example, advance it in a few years, and you could make genetically identicle livers and kidneys. Or a new pancreus, good for some insulin goodness, and help the adult onset diabeties.

    --
    3 degrees of separation from Vladimir Putin
    1. Re:Not always... by geekoid · · Score: 2, Interesting

      " Make a slit in egg, remove nucleus."

      That would be the tricky part. No one can do this yet. Suk claimed to, but it turns out he was a big fat liar. On the plus side, this shows that the scientific method of publication works.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
  9. It's only voodoo... by jd · · Score: 2, Funny

    ...if the bone cell has a top hat and tap-dances to Live And Let Die.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  10. Much hype about nothing. Here is why. by Anonymous Coward · · Score: 5, Informative

    I hope the following make it clear that stem cell research of any form does NOT need, or involve, the destruction of an embryo. Current hype is used specifically to harvest the votes of well-meaning, but maleducated populace.

    IMACB (I Am A Cell Biologist), and I suggest you also look some of this up in your college-level bio text, or talk to a bio prof, they will love it:

    1) Absolute majority of stem cells are not people, and cannot be grown into them.
    2) The only stem cells that can be grown into a human being are the omnipotent cells created within the first 2-3 cell divisions past the fertilization.
    3) Any cell harvested after the 8-cell stage becomes pluri-potent, and can grow into adult human tissue, but will NOT form some of the embryonic tissues, such as placenta, under any condition (no placenta-> no new human possible).
    4) Stem cells harvested from tissues of adults are called adult stem cells (d'oh); these are multi-potent, meaning they can only make some, but not all, of the tissues of an adult. E.g. bone marrow stem cells will only make blood cells.
    5) Under some conditions, adult SCs of one tissue type may be coaxed into turning into another developmentally related tissue type (e.g. skin SCs may be grown into neurons). Like cells in 3), these will never directly grow into another human.

    In terms of usefulness:
    1) Adult stem cells are hardest to control, and are least promising for research, but may help combat some types of cancer.
    2) Pluripotent stem cells are easiest to manipulate and will have lots of applications in geriatrics, damage reconstruction, cancer, AIDS, etc. People I personally know have shown that these may be used to treat Parkinson's (in rats), as well as replace ischemia-induced brain damage (a group rebuilt a damaged brain in mice); clearly there are lots more things going on, but application to humans will require volunteers, changes in law, and massive infusions of cash.
    Most importantly, acquisition of these cells does NOT require the destruction of embryos. One could harvest these cells, and the embryo will (to the best of our knowledge) develop normally. Vital extraction is more expensive, however, and does carry some risk to the embryo. Additionally, using such extracted cells will not destroy a human life, since a human cannot be grown from such cells, under any conditions.

    3) Cells from before the 8-cell stage of embryo developments are as powerful as cells in 2), but are harder to control. While these may also be harvested with little side effects (can take one for research, leave 7, and these 7 will still grow into a normal baby), the one cell we take out can also be grown into a baby, hence some might call it "destroying life", but common sense here suggests the original embryo will survive, so "borrowing" that one cell is not killing life.

    Bottom line? Stem cells do not need to involve destruction of embryos. We have the technology to only "borrow" some of the cells from a human embryo, and let it develop normally. The reason surplus embryos (from in vitro fertilization treatments and such) are currently destroyed after harvesting is because whoever donates those embryos does NOT want them back. It is trivial to just "borrow" a few cells and give back the embryos to implant.

    Once again, stem cells !=destruction of life.

  11. Why we dislike Christianity by Harmonious+Botch · · Score: 3, Insightful

    We do not dislike it because it is stupid, anti-scientific, etc. We dislike it because many of the most vocal followers are stupid, anti-scientific, etc AND they interfere with our lives. It's not the holding of opinions that bugs us, it's the actions.
    I can get along fine with a Christian who minds his own business.