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Star Trek's Synthehol Now Possible?

[TheBORG] writes "Professor David Nutt, a psychopharmacologist at the University of Bristol in the UK, believes that there is no scientific reason why 'synthehol' (a science-fictional substitute for alcohol that appears in Star Trek:The Next Generation television series) cannot be created now. It will allow drinkers to experience all of the enjoyable, intoxicating effects of alcohol without unpleasant side-effects like hangovers." Of course, there's still the real deal, Romulan Ale, for when you want a splitting headache in the morning.

22 of 509 comments (clear)

  1. Drugs. by Anonymous Coward · · Score: 5, Funny

    Synthehol is my anti-drug.

  2. Re:Actually by jpardey · · Score: 5, Funny

    Some nerds know about biochemistry and how to make alcohol have a lower toxicity... and some nerds know about star trek.

    --
    I have freaks! I did something right...
  3. How About... by Scarletdown · · Score: 5, Funny

    Romulan Ale is okay, but real life forms prefer the Pan Galactic Gargleblaster, for when you want to feel like you have had your head smashed in by a slice of lemon wrapped around a large gold brick.

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    This space unintentionally left blank.
    1. Re:How About... by LithiumX · · Score: 5, Funny

      The main difference is that while the PGG is legal in most of the more liberal parts of the galaxy, Romulan Ale is illegal, which is part of it's attraction (much like a Cuban cigar - it's the law that makes them taste so damned good).

      On the other hand, Romulan Ale doesn't leave you reeling like a man being mugged in a meadow, doesn't eat through the table when spilled, and never ever made anyone yell Pheoww in minor thirds.

      --
      Do not confuse "Freedom of Choice" with "Free Will".
  4. Oh no... by likwidoxigen · · Score: 5, Funny

    Speaking from the perspective of an American College student whom is reasonabally responsible. DO NOT REMOVE THE HANGOVER! I can only imagine how little work I would get done, and how many more students would fail out of college. There needs to be a bit of punishment, or else mass irresponisbilty would follow.

    --
    Walk with me or walk behind.
  5. Re:Actually by LithiumX · · Score: 5, Informative

    Synthahol got you drunk in Star Trek, but it was described as something that could be shaken off more easily than true alchohol (ie you can actually get sober quickly, as opposed to just thinking you're sober) and having "less" hangover afterwards. It was also suggested multiple times that it was primarily a shipboard/on-base beverage meant for off-duty Starfleet and other personell... with the real thing being in common consumption for civilians.

    As for taste, I get the feeling it didn't simulate it all that well (considering Scotty's reaction to it on that TNG episode. I'm a geek, but not geek enough to know the episode number).

    --
    Do not confuse "Freedom of Choice" with "Free Will".
  6. Re:Great... by r00zky · · Score: 5, Insightful

    Sorry if I seem a tad against the idea... but I think alchohol is a waste of time and money that could better be used to improve oneself and the society in which they live.

    The same could be said about Slashdot but you still post in here.

    --
    I'm a chainsmokin' alcoholic sociopath, so-ci-o-path
  7. Re:One good reason it'll never happen... by gbobeck · · Score: 5, Insightful
    ...do you really think that any government is going to allow another synthetically produced substance that alters your mood in any way whatsoever?


    Hmmm... lets see: Prozac, Ritalin, Celexa, Lexapro, Paxil, Pexeva, Zoloft, Elavil, Norpramin, Tofranil, Aventyl, Pamelor, Wellbutrin, Cymbalta, Effexor...
    --
    Navicula hydraulica plena anguilarum est. Omnes castelli tuus nostri sunt. Ed elli avea del cul fatto trombetta.
  8. In the name of science by Thnikkaman · · Score: 5, Funny

    If the inventors would like to send me a few kegs, I will consume them. Purely in the name of science, of course.

  9. TNG 6x04 by XanC · · Score: 5, Funny

    Duh!

    1. Re:TNG 6x04 by Anonymous Coward · · Score: 5, Funny
      WOOOOP. WOOOOP. WOOOOP.


      Lonestar: What the hell was that?


      Dot: That was my virgin alarm!

  10. Re:Yah, alcohol by Anonymous Coward · · Score: 5, Interesting

    I'm posting this anonymously, because I'm an addict.

    You have some good insights into the problems of the addict, even if you don't or can't understand what it's like to be one, as you imply.

    The underlying drive of the addict is not so much to feel good as it is to feel differently from what ever base state they are used to feeling (unhappiness). Any feeling is better than the underlying feeling of unhappiness, even total lack of feeling. (It's interesting that at the same time, many drunks tend to extreme emotions of anger or sentimentality.)Some of us have drugs of choice, such as alcohol, speed, marijuana, etc., while others of us will imbibe anything and everything they can get their hands on.

    I wonder if anyone will ever be able to create an alcohol that is safe for alcoholics to drink. Even if they can find away not to trigger the physical craving response by some subtle manipulation of the molecules, how can they remove the powerful psychological urge?

    I could ramble on, but in short, I don't think this represents any sort of cure for alcoholism. It might be a great boon for non-alcoholics to enjoy, but this won't stop the progressive spiral of destruction of a person addicted to alcohol.

    Anyway, I just thought I'd share that with you. You've always seemed like the decent sort, KFG.

  11. Beg to differ... by Aphrika · · Score: 5, Insightful

    ...but I had lectures from him and he's really rather good and certainly knows his stuff. If you want to knock him for his name then fine.

    A psychopharmacologist is interested in why and how chemicals interact with the brain and nervous system, so it's quite within his mandate to speculate on how something like 'synthehol' should theoretically be possible. Invariably you tend to find that postgraduates in the UK have to write papers on how something is theoretically possible in order to attract funding for research.

    These papers are in the public domain, so if some Sci-Fi fan for LiveScience breaks the news with the sensationalist title "Hangover-free Buzz: Star Trek's Synthehol Now Possible" while at the same time quoting passages from the paper like "Some "partial agonists" of GABA-A receptors already exist; bretazenil and pagoclone were developed as anti-anxiety drugs. These drug molecules are instantly reversible by the flumazenil, used as an antidote to overdoses of tranquillisers.", I'd wager that you should be shooting the messenger here, not the scientist.

  12. Re:Nutt? by commodoresloat · · Score: 5, Insightful
    the only thing more pointless than reading articles about things that "should" "theoretically" be "possible" is writing them.

    Not to stomp on a good put down, but the only reason many things are possible today is because someone wrote "pointless" articles about them when they were only theoretically possible.

  13. Re:Who'd use it? by MadCow42 · · Score: 5, Insightful

    >> Now, be honest, do you really drink for the taste? If someone suggested fruit juice instead of wine what would you think?

    Yes, I do. I quite enjoy scotch, but rarely have more than one or two a week... I do drink it purely for the taste (one drink is hardly enough to get a buzz, let alone get drunk). When I drink beer, I also rarely have more than one. As difficult as this may seem to you, it's fairly normal with most people I know. My generation (born in early 70's if you ask) doesn't seem to have the "drink a few every night after work" mentality that our parents did. Maybe I live in an exceptional microcosm... who knows.

    As for fruit juice... I don't particularly like the taste, sorry. If it were as complex and enjoyable as Oban or Lagavulin, maybe I'd buy it by the gallon.

    MadCow.

    --
    I used to have a sig, but I set it free and it never came back.
  14. Re:Great... by rohan972 · · Score: 5, Funny

    We human beings need stress reduction. Many of us choose to drink a moderate amount to do so.

    And there are also those of us who never use it for stress reduction, but do use it to celebrate! I like a quote I heard from a pastor one day "Jesus turned water into wine, and evangelical christians have been trying to turn it back ever since"

  15. Re:My Preference... by Anonymous Coward · · Score: 5, Funny

    In Soviet Russia, the Pan Galactic Gargle Blaster beats YOU!

    No wait. It does that everywhere.

    Witty but useless comment defeated! Argh!

  16. Re:It'll never happen... by Siffy · · Score: 5, Funny

    the US is STILL recovering from the effects of alcohol prohibition

    I don't think we're ever gonna be able to get rid of NASCAR now.

  17. Re:Yah, alcohol by Anonymous Coward · · Score: 5, Interesting

    I like your comment, so I'll post my story. I've suffered from social anxiety since I was 15 or so and, like most people with this problem, quickly found that alcohol kicked the anxiety away. Being aware of the potential problem I could get into if I started drinking regularly I did some research, and found what at the moment looked like a panacea: GHB. No hangover and presumably no addiction. Little did I know that 2 years down the road of using it daily I'd face a living hell trying to quit. Not so much the psychological aspect (it had long stopped being enjoyable) but the physical dependency. I made it and had to spend 2 years with psychotherapy to learn how to live with anxiety. The anxiety is no longer a problem and I can lead an almost normal life now. I live on my own and have a good paying work. I've never had a date though and, being 30 already, have mostly given up. To get to the point, not being to function with the aid of a drug is a situation people who don't need it can't imagine.

    I want to wish you good luck in kicking alcohol. Things like having a pet and listening to music helped me a lot.

  18. Re:Actually by MadCow42 · · Score: 5, Funny

    Sinthehol = synthesized alcohol replacement

    Sinthehole = personal entertainment device for Slashdot geeks.

    One may lead to the other, but I don't think they're the same thing. :)

    MadCow

    --
    I used to have a sig, but I set it free and it never came back.
  19. Re:It'll never happen... by Anonymous Coward · · Score: 5, Informative

    It's probably entirely pointless to debate this here, but what the hell. I'm bored.

    No darling, it's an order of magnitude 'stronger' (higher THC) then a generation ago.

    False. There is no proof that marijuana on the market today is, on average, stronger than that in the mid or early 80's, or even 70's/60's. You're buying the B.S. that the U.S. Gov'ts failing drug czar's office wants you to buy. If you look at the figures they use to try and promote this myth, you will realize a few things. First of all, the method used to determine the concentration of THC way-back-when was inconsistent, it was not always used on fresh stashes, but rather very stale stashes (THC breaks down over time) and even on feral hemp, which containts hardly any THC. So on average, they claim that marijuana of the past had less than 1% THC content. There's a problem with this though. You can't get stoned on 1% or less THC. You're brain doesn't notice it. So either the hippies of the past were hallucinating the effects of marijuana (which I wouldn't entirely rule out considering the high use of acid...), or else, you got it, there was more THC in marijuana back then than the officials want you to think there was.

    Second of all, there are anectdotal researches that show that with older age, lower doses of THC have higher effects on the brain. That is one reason why people that were hippies back in the 60's find todays marijuana to be stronger. It's not really stronger, they're just getting a much better ROI thanks to their aging.

    And finally, lets just pretend for a moment that marijuana IS much stronger today. Say, 10 times stronger. It still wouldn't matter. Unlike alcohol, where drunk people consume more and more and next thing you know they're wasted, marijuana does not have these effects. Users stop smoking after a certain level of intoxication is achieved. Individual users will have different requirements. Some would want to get a mild buzz, others may want to get stoned off their ass. Either way they'll stop smoking after they achieve that level. The total intake is the same. So what you may be able to say is that high THC varieties are SAFER than old, low THC varieties, as the total amount of smoke ingested is LESS.

    With that in mind do you think comparing what is on the market today with that of 40 years ago is particularly accurate?

    Again, no I wouldn't, if your comparison involves logical falacies and down right illogical thinking. The basic FUD spread by the drug czar is that:

    Today's marijuana has more THC, so it is more dangerous than previous hippy generations had it.

    The problem here is that the underlying assumption is that THC and marijuana in general is dangerous. This has not been proven. At all. Not in the slightest. There have been no fatalities from recreational use of marijuana. Smoking and driving, while undesirable, does not have the same effect as drinking and driving. Traffic accidents involving parties that were ONLY smoking pot are actually less likely than totally sober traffic accidents. Taking a sample of traffic accident fatality victims that had traces of THC in their blood (I'll skip the fact that the sampling method is inacurate), the majority of these people also had some other intoxicating agent present, alcohol being at the top of the list.

    Wouldn't you be just a bit concerned about any neuropharmacological agent that was delivered in a random dose, from implicitly suspect sources, that had been bred up so quickly with such little good research?

    There is more than enough anectdotal and scientific proof that marijuana is not dangerous. However, you have a point. Black market marijuana may not be terribly safe, due to the nature of it being entirely un-regulated in it's final sales form. There could be plenty of insecticides used on it, or, like there have been a few (very few) reports of angel dust laced marijuana. That angel dust will REALLY fuck with you.

    What you put into y

  20. Just what we need... by slapout · · Score: 5, Funny

    ...a bunch of drunk people running around with phasers shouting "Make it so!"

    --
    Coder's Stone: The programming language quick ref for iPad