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First Embryonic Stem Cell Clinical Trial Imminent

An anonymous reader writes "California-based Geron has announced that the first embryonic stem cell trial may be in the not-so-distant future. Tom Okarma, Geron's CEO, recently announced that the company will be seeking permission from the FDA to begin clinical trials. From the article: 'Geron's plan is to treat people that have acute spinal injuries with oligodendrocyte progenitor cells grown from human ESCs. Oligodendrocyte cells support neurons in the brain and spine by sheathing them in myelin, a fat that helps neurons to transmit signals.'"

8 of 224 comments (clear)

  1. Result of Propostion 71? by gasmonso · · Score: 4, Informative

    I believe this was the result of propostion 71 that was passed in California last year. It allocated $3 billion over a period of ten years to fund stem cell research! Way to go California :)

    http://religiousfreaks.com/ http://psychicfreaks.com/
  2. babybooms, as we age, will need these technologies by Anonymous Coward · · Score: 4, Interesting

    With the babyboomers being the first generation (in history) to be at the threshold where science and technology is unlocking the secrets of how cells work and with the increased competition, it is no longer simply okay to accept that when you reach your early 40's that you can be let go because there are younger workers able to do your job (simply because you suffer fron the what is now "natural" aging process)

    With these new upcoming technologies (stem cells, bio/nanotech) we will be able to, in the next couple of dacades, to slow and reverse the aging process so that in this competitive world enviroment, you won't be tossed out on the junk heap when you reach 40.

    The only way this is going to happen is for people to push science and technological research forward and demand that this be done (instead of, say invading other countries).

    Remeber, in the future, when we can reprogram cells and easily as we write programs today, people growing up will be taking their nano-reguvination/enhaced intelegence/memory/internet-connect-mind-thought-t ransfer pills and much like todays generation (with ipods, pc's,internet etc.) not be able to imagine a time when this technology did not exist.

  3. Re:Alcomohol by dfedfe · · Score: 5, Informative

    Ethanol does have an effect on transmission (specifically it reduces excitability and increases the effectiveness of GABA, an inhibitory neurotransmitter), but those are effects on action potential generation. Myelination from oligodendrocytes just increases the ability of an already generated action potential to reach the end of the axon and cause synaptic activity. So the oligodendrocytes' effect is sort of like plugging holes in a leaking pipe, whereas the effect of alcohol is more like decreasing the chance that water will actually enter the pipe in the first place. Which is to say: alcohol's work is already done before the myelination comes into play, so increasing the latter won't much affect the former. (IAA neuroscientist, but admitedly this isn't my area of expertise so I may be slightly wrong).

  4. Re:Just a thought.... by thule · · Score: 4, Insightful

    But what I'm really afraid of is that, despite whatever scientific significance such a trial could have, the religious right will immediately jump on this and squelch it without giving it any sort of chance. At least, hopefully, we can get the scientific advances later from countries that are more willing to do the research.

    What frightens me is that even with proven advances in adult stem cells, some people squelch it for research that has inherent problems with the body rejecting the cells. These people claim that anti-science religious groups are attacking them. Huh?

  5. Re:babybooms, as we age, will need these technolog by Quirk · · Score: 4, Funny
    "...we can reprogram cells and easily as we write programs today,

    Sure that's a third eye on your elbow, but it's a feature, for free too.

    --
    "Academicians are more likely to share each other's toothbrush than each other's nomenclature."
    Cohen
  6. Re:Move along... by bsartist · · Score: 4, Funny

    It takes a lot of backbone to make a joke like that. I'm amazed someone had the spine to do it.

    --
    Lost: Sig, white with black letters. No collar. Reward if found!
  7. My fellow republicans ... by Surt · · Score: 4, Funny

    My fellow republicans, it is time we got out our pitchforks and torches. The mad scientists are going too far, and frankly, I think we all know we're overdue for some lynchings. God didn't put us on this earth to suck cells out of unborn babies to heal the sick, but he gave us fire for good reason, and it is time we used some of it!

    --
    "Who is the Journal of Quantum Physics going to believe?" --Stephen Hawking
  8. Re:Move Further... by Pedrito · · Score: 4, Insightful

    I know that our pharmacological community is more concerned with making a buck and keeping us sick then actually curing diseases.

    That's a pretty ridiculous thing to say. Yes, pharmaceutical companies want to make a buck, but scientists are human beings and many of them are doing their best to create the best drugs they can to help people. To think that they're intentionally withholding drugs or not trying to cure diseases to keep making money is simply ridiculous and paranoid.

    There are tons of people working to cure cancers, Parkinson's, AIDS, Alzheimer's, and other diseases. If you think otherwise, you don't know anything about medical research. The fact that these things aren't yet cured is not from a lack of trying. There's still a great deal about the human body we don't know. There's tons about stem cells we don't understand. The human body is so amazingly comlpex, it's incredible that we can do the things we can do already.

    Remember, drug companies and researchers came up with a number of vaccines for diseases that no longer plague us. Bacterial infections are fatal about 1/1000th as often as they used to be, thanks to the work of drug companies.

    Don't get me wrong, they're not charity organizations and I'm not trying to make them out to be that. They're trying to make money for their stockholders, and that's their job. The people who work for them are trying to cure diseases, though. That's their job.