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New Alzheimer's Drug Shows Promise

An anonymous reader writes "The Herald Sun is reporting that researchers may have some progress to report on the Alzheimer's front. A new drug, called PBT2, was developed by a Melbourne-based biotech firm that has been showing some promising results. From the article: 'Early clinical testing has confirmed the drug is fast-acting. Levels of amyloid dropped by 60 per cent within 24 hours of a single dose. It found also that PBT2 suppresses the impairment of memory function. More human studies begin in Sweden next month and Australians will join a major international trial of the drug next year.'"

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  1. animal data not clinical trials? by simong_oz · · Score: 5, Informative

    From the article: 'Early clinical testing has confirmed the drug is fast-acting. Levels of amyloid dropped by 60 per cent within 24 hours of a single dose. It found also that PBT2 suppresses the impairment of memory function.

    The article seems to be wrong - press releases on the Prana Biotechnology website indicate these results are from studies in mice.

    More human studies begin in Sweden next month and Australians will join a major international trial of the drug next year.

    If the data is from mice, then the above clinical trial is presumably a phase I clinical trial, which is designed to show safety and not efficacy. It could be a while before human data is available.

    Of course, none of this will stop investors believing the article ;-)

    --
    "Because it's there." - George Mallory, when asked why he wanted to climb Mt Everest, March 18, 1923 (New York Times)