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The Next X Prize
BlueCup writes "The X Prize Foundation, sponsor of a widely noted 2004 award for developing a reusable rocket suitable for private space travel, says it is now teaming with a wealthy Canadian geologist to offer $10 million to any team that can completely decode the genes of 100 people in 10 days. And that's not all. As an encore, the winning team will be paid $1 million more to decode another 100 people's genes, including a bevy of wealthy donors and celebrities. Already accepted for future decoding: Google Inc. co-founder Larry Page, Microsoft Corp. co-founder Paul G. Allen and former junk-bond king Michael Milken."
Before this turns into a large nature vs. nurture argument, I thought I'd pipe in here with a really great paper that really throws a wrench into the argument.
In one of the largest Nature vs. Nurture shakeups, it was shown that the maternal behavior of the mother can cause epigenetic variations in the child that ultimately cause the child to grow up to become a nurturing mother or a non-nurturing mother (http://www.neurobio.ucla.edu/~lmp/Meaney.pdf ). This is one of the biggest breakthroughs in Neurobiology connecting specific epigenetic alterations to behavioral response (yes, there were controls, switching mothers/children, read the paper for the full details).
However, the genetic alterations here are not on the sequence level, but rather on the Epigenetic level (the state of the DNA). Therefore sequencing the genome of two identical twins who had different mothers (one nurturing, one non-nurturing), can lead to entirely different epigenetic levels, yet the sequences would be identical. The take home message here is that while the underlying sequence is important and full sequences will certainly help in the understanding of biology, the underlying state is just as important. This epigenetic variation is also one of the causes of cellular differentiation (stem cells, etc.), and also certain cancer types. In an effort to make my post slightly controversial, I'd go as far to say that a high throughput epigenetic snapshot is probably more important for understanding success in individuals than the underlying DNA sequence (however, it is my hope that a high-throughput sequencing approach would be a first step towards a high-throughput epigenetic approach, as they are tightly coupled in a sense)-- as well as providing great breakthroughs in other areas of biology (tissue regeneration, cancer treatement, etc.).
how does one become a wealthy geologist?
Google "Fort McMurray"