Keeping Cool May Be the Key To Longevity

merryprankster writes "New Scientist reports that Scripps Research Institute scientists have found that lowering the body temperature of mice by just 0.5C extends their lifespan by around 15%. Until now the only proven way of increasing longevity has been calorie restriction — but as this also causes a lowering of body temperature the researchers speculate that this cooling may be the underlying mechanism retarding aging. In this study mice with a defect in their lateral hypothalamus, which has the side effect of cooling body temperature, not only lived longer but also ate normal amounts."

Comments

Don't Get It Backwards

[kthejoker]

Lest we be fooled, lowering your body temperature as a warm-blooded person is impossible. What the researchers actually did was artificially inject a protein that when unfolding generated higher amounts of heat than normal proteins into the hypothalamus. This tricked the mouse's brain into lowering its internal thermostat.

This is more like holding a match to a thermometer which can trigger a fire alarm. It's fooling a local sensor to simulate a global sensation.

So you can't eat ice cream, or live in Antarctica, or whatever to fool it. You have to trick your brain. Even better, at this tricked out brain level, you need less calories to survive because your brain doesn't turn on its "must store fat" warning level as quickly. So this might be a good cure for obesity in the future.

But seriously, how cool is it that they can use a heat-generating protein to trick a mouse's brain? I love how neurology proves how gullible we are.