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Engineered Hens Lay Cancer-Fighting Eggs

celardore writes "Hens that lay eggs containing cancer-fighting proteins have been developed in Scotland. While not themselves cancer-antagonistic, the proteins can be used to create drugs that have cancer-fighting potential. The hens are, in effect, factories for cancer drugs. It is still unknown whether the resulting drugs would work in practice, and clinical trials are 5 years off. This research was conducted by the Roslin Institute, the ones responsible responsible for Dolly the sheep, the world's first cloned mammal."

16 of 92 comments (clear)

  1. So which came first? by Timesprout · · Score: 3, Funny

    The protein or the cancer?

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  2. Re:The modified chicken came first! by debilo · · Score: 2, Informative
    So once again, someone who thought he has solved the chicken and egg problem was wrong!

    I've never understood all the fuss about the chicken and egg problem - they both taste great.
  3. the question remains by macadamia_harold · · Score: 5, Funny

    The hens are, in effect, factories for cancer drugs. It is still unknown whether the resulting drugs would work in practice, and clinical trials are 5 years off.

    Clinical trials are 5 years off? What are they, chicken?

  4. I will not eat... by p0rnographer · · Score: 3, Funny

    green cancer fighting eggs and ham...

  5. Re:Responsible? by funfail · · Score: 3, Funny

    It is a cancer word that uncontrollably reproduces.

  6. Lame Star Trek Joke... by __aaclcg7560 · · Score: 2, Funny

    Laying an egg is a job where no engineer has gone before. :P

  7. Okay, no serious posts yet, so I'll bite by alshithead · · Score: 5, Insightful

    This has the potential to be a great advance in medicine and science related to cancer. Those of you who are trying for funny or sarcastic posts...would you rather have an option other than dying if you were diagnosed with cancer? I know that some folks out there won't be happy due to manipulation of "God's creatures" but if my wife, parents, or me was diagnosed with cancer, I would want as many options available as possible. This really is a potentially huge step in fighting cancers. It is especially important when you consider how few options there are in fighting most types of cancer. Chemotherapy is a long shot most times and makes you sick as hell before you MIGHT get better. Surgery has many shortfalls besides being invasive. This could be a huge step in making cancer a problem with much better odds of beating.

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    1. Re:Okay, no serious posts yet, so I'll bite by KokorHekkus · · Score: 2, Insightful

      I agree with you but I guess that genetically modified cows would be a better source for tailored proteins. If there is a problem with getting enough viable animals (as has been with cloneing) to produce these tailored proteins then cows should be able to make massive amounts of these over their lifetime compared to chicken.

      As for the "rightness" of manipulating animals to produce these proteins I think it's way more justified than just using them for our food. Any animal actually producing medical help will be a much better treated than ordinary farmstock because they're so much more valuable to us.

      Not a vegan/vegetarian/whateverian. Farm animals have their place in the food chain. Let's not just take it to extremes.

    2. Re:Okay, no serious posts yet, so I'll bite by Nutty_Irishman · · Score: 2, Interesting

      Dealth is something we all have to face some day. Whether it be from Cancer, Heart attack, or a car accident. We joke about it because it's our way to relate to something that we know will happen to us.

      Me, I'm not worried about death itself, but the way I go. Every 10 years, the average life expectancy increases by 2 1/2 years-- yet very little has been done to increase the quality of life in our later ages. I'd rather die young while my quality of life is good than older stuck in a nursing home having some one take care of me. We can make as many miracule drugs we want that prolong the life of an individual, but if we don't do something to make that life worth living for, then we have defeated the purpose. That's why I view stories like these as bittersweet.

  8. This guy goes to a psychiatrist by iminplaya · · Score: 4, Funny

    and says, "Doc, uh, my brother's crazy; he thinks he's a chicken." And, uh, the doctor says, "Well, why don't you turn him in?" The guy says, "I would, but I need the eggs."

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    What?
  9. Re:Eggs? by Anonymous+McCartneyf · · Score: 3, Informative

    For one thing, it's easier to keep egg whites contained.
    You get a lot of egg white at once. Chickens lay lots of large eggs, and the ones allowed to grow up to be chickens lay lots more large eggs. Each egg contains more white than the average petri dish can hold.
    It's also simpler to feed a chicken than to feed a petri dish.

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    There is a fine line between recklessness and courage... -- Paul McCartney
  10. Who came first? by ubuwalker31 · · Score: 4, Funny

    A chicken and an egg were lying in bed, the chicken sitting back, leaning against the headboard with a big grin on his face.

    The egg, looking quite angry and disappointed, rolled out of bed and said, "well I guess we answered that question!".

  11. Re:you're screwed by Gryle · · Score: 2

    Well that goes without saying.

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    Only two things are infinite, the universe and human stupidity, and I'm not entirely sure about the universe - Einstein
  12. Re: KFC by tomhudson · · Score: 3, Funny

    Their importance as a medicinal source makes them much more valuable than just another KFC bucket.

    I'm still waiting for them to cross chickens with octopii ... everyone gets a drumstick.

    Chickens are better than cows. The furst words of the article summary:

    "Hens that lay eggs containing cancer-fighting proteins ...

    Somehow, I don't see cow eggs as being able to compete, either in quantity, or in ease of access, to hen eggs :-)

  13. Re:you're screwed by 6ame633k · · Score: 2

    ummm...you don't eat them - the proteins (interferon b-1a, miR24) are extracted from the egg whites and used in creating treatments for various types of cancers as well as other diseases such as MS. I imagine it's less expensive than creating those proteins artifically in a lab like *i think* they do for insulin (also a protein) ...that's kewl.

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    You had me at merlot
  14. Re:5 years. at least. by kokyuho · · Score: 2, Interesting

    Ho Hum. Nice article but a bit anticlimactic. These guys are NOT the first to do this. Roslin institute is more than a year behind at least one other company. A good friend of mine, by the name of William MacArthur who is a brilliant Molecular Biologist, founded a company called Geneworks in Ann Arbor, Michigan several years ago with the goal of creating transgenic chickens that do exactly the same thing as the chickens described in the article. He succeeded and more than a year ago had pure-breeding, transgenic chickens. Before anyone else in the world. He had been in regular contact with Amgen, Genentech, and all the "Big Boys" and also received FDA certification. In addition to creating the chickens, he developed a simple and cheap way of extracting whatever protein had been created from the egg. His company had either one or two huge chicken barns in Southeastern Michigan and they just needed a bit more capital to make it "over the hump" and really take off. Ironically enough, none of the big companies would give him the relatively small amount of capital that he needed to continue because, as he explained it to me, their risk assessment programs were all based on drugs manufactured in a drug factory and as such, they had no way to evaluate his new methods, so they wouldn't give him any funding and Geneworks had to shut down in August 2005. I happened to stop in at their offices as they were loading up the equipment and getting ready to auction it off. However some of his transgenic chickens were donated to a university (I don't remember which one) so that the line could continue. By the way the folks at the Roslin institute know who Bill Mac Arthur is and what he was able to do.