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Cancer Drug May Not Get A Chance Due to Lack of Patent

theshowmecanuck writes to mention that in a recent study, researchers at the University of Alberta Department of Medicine have shown that an existing small, relatively non-toxic molecule, dichloroacetate (DCA), causes regression in several different cancers. From the article: "But there's a catch: the drug isn't patented, and pharmaceutical companies may not be interested in funding further research if the treatment won't make them a profit. In findings that 'astounded' the researchers, the molecule known as DCA was shown to shrink lung, breast and brain tumors in both animal and human tissue experiments."

3 of 471 comments (clear)

  1. Re:Generic drug manufacturers by jfengel · · Score: 5, Interesting

    It's not just their lack of expertise. Getting a drug through level 3 trials is expensive: it takes a lot of (often paid) subjects, and doctors and nurses to spend time with those subjects, and a battery of tests to be done on those subjects. This money is spent over years to ensure that the pill is safe and effective before you have even a single paying patient. Paying the subjects is actually the cheap part.

    And there's the possibility that once they've spent all that money, it could fail. Maybe the pill just doesn't work. Maybe there are side effects: look at the way Merck is getting hammered for producing a highly effective pill (Vioxx) that just happened, to, well, kill a few people.

    Barr makes their money by letting somebody else pay for all that, and then coming in a few years later and charging a lot less. It's the usual problem: the second pill costs $.49, but the first pill costs $75,000,000.

  2. Good thing this is in Canada... by Arrgh · · Score: 5, Interesting

    ...where we believe that governments have a responsibility to set policy for, and even fund, public health initiatives that are not necessarily advantageous to any given industry sector or corporation.

    The research in question was funded by a Canadian federal government agency, and I'm certain that one or two well-funded, non-profit and/or public sector agencies will step up to the plate to study whether the proposed treatment is safe, and if so, some smart non-intellectual-property-driven and yet profitable organization will market it.

  3. Re:Am I missing something? by 6ame633k · · Score: 5, Interesting

    Perhaps Health Insurance Companies could fund this type of research - they would stand to benefit directly due to the high costs associated with cancer treatment.

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    You had me at merlot