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'Virus Sponge' Could Improve Flu Treatments, Diabetes Care, Vaccine Development
University of Maryland researchers have announced a new "virus sponge" that could aid in the treatment of, among other things, avian flu. The sponge woks similar to kidney dialysis, filtering the harmful virus from the blood. "The virus sponge is based on a technology called molecular imprinting. In molecular imprinting, researchers stamp a molecule's shape into a substance (in this case, a hydrogel--a sponge-like material). When the specific molecule filters through the hydrogel, it fits in the imprint hole and is trapped."
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Selectivity is most important. It's great that this gel can 'capture' virus proteins, but does it bind them more tightly than other proteins? This could be very problematic if it removes native proteins in the human serum. Many proteins look alike structurally at low resolution -- nm resolutions. If this system doesn't discriminate based on other factors like electrostatics, then this couldn't possibly be an effective filter.
The next problem is accessibility. I'm assuming that this gel only traps proteins outside of cells. I'm not a virologist (I'm structural biologist & biophysical chemist), but it seems to me that if a virus has integrated itself into your genome or populated most of your cells, you're screwed.