The Secrets of Firefox about:config
jcatcw writes "While Firefox is very customizable, many of its settings aren't in the Options. Each setting is named and stored as a string, integer, or Boolean in a file called prefs.js and accessed via about:config from the nav bar. Computerworld provides instructions on 20 tweaks for speeding up page loads, making tabs behave, reducing memory drain, and generally making the interface act the way you want it to. Customization also comes through the must-have FF extensions (but be sure to skip these)."
here
Well, a lot of these "tweaks" will have negative effects.
Example: nglayout.initialpaint.delay as 0. This will slow rendering of the page as it causes reflows. Fools.
http://kb.mozillazine.org/About:config_entries
Sigs are too short to say anything truly profound so read the above post instead.
From RFC 2616 (HTTP/1.1) section 8.1.1: