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Team Claims Synthetic Life Feat

gertvs writes "According to the BBC scientists in the US have taken a step towards producing life from scratch in the laboratory by having successfully transplanted an entire genome from one bacterium cell to another. This technique could possibly lead to the creation of 'designer' microbes producing fuel or help cleaning toxic waste. 'The ultimate plan is to stitch together artificial chromosomes, proteins and other building blocks with the aim of jumpstarting their designer microbe to life. But Dr. [Craig] Venter concedes that this may be a long way away, but he says he has taken an important key step towards that goal. His team, essentially, snatched the body of another life-form and invaded it with a new genetic code. This, he says, will be a key tool in testing the artificial chromosomes - or DNA bundles - he plans to make. '"

13 of 112 comments (clear)

  1. Origins Of Life? by Umbral+Blot · · Score: 3, Funny

    Reminds me of a certain cartoon: http://www.angryflower.com/goinaf.gif

  2. Patents.... by king-manic · · Score: 4, Funny

    Wait didn't another firm patent artificial life. The gall of these people, working hard to create something new. Thats simply un-American. They should really make vague patents wait for someone else to do the work and sue.

    --
    "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy."
  3. Re:Inteligent design by stoolpigeon · · Score: 2, Insightful

    I don't see how. They didn't actually create life from scratch - they took a step towards it. They took one form of already living thing and moved it to something else - by design, using their brains. I'm not advocating intelligent design here- or trying to start an argument about it - just pointing out that this development doesn't seem to really 'put a big hole' in that idea.

    --
    It's hard to believe that's how Micronians are made. Why don't we see it right now by having you both kiss one another?
  4. i am... by cosmocain · · Score: 2, Insightful

    ...almost sure, that we will se a whole lot of paired headlines.

    "designed microbe is able to clean water from toxic waste" and a few months/year later: "water-cleaning microbe causes " and some random illness/problem. genetic engineering is full of possibilities, it's the humans that haven't shown responsible behaviour with new technologies.

  5. Imagination needed by Anonymous Coward · · Score: 2, Funny

    This technique could possibly lead to the creation of 'designer' microbes producing fuel or help cleaning toxic waste.

    Oh come on! Have an imagination! This could make some really killer bioweapons! Or we could mine deer for oil. Convert puppies into kittens. Give George Bush a brain. Think of the implications!

  6. The Venter Institute by poopdeville · · Score: 2, Funny

    This is very exciting. I took a class from someone who ended up working at the Venter Institute, so I'm pumped to see that they've made major progress.

    On the other hand, the field of Artificial Life is small. Something on the order of a thousand other people are qualified to talk about this intelligently. So my hopes for discussion are pretty much nil.

    --
    After all, I am strangely colored.
    1. Re:The Venter Institute by NeverVotedBush · · Score: 2, Insightful

      You have to be talking about Stephen Wolfram.

      OK, Craig Venter is humble compared to that moron. Smart - but still a moron.

  7. So they pretty much did... by arakon · · Score: 2, Informative

    what a Virus already does. They took DNA, and implanted it into another cell and the cell ran the DNA instruction set... Just like cells are wont to do. Seems like a pretty "Cut & Paste" idea to me; hardly "creating Life", or even steps toward it.

    We'll have Artificial Intelligence (synthetic life by my standards) I think, long before we're actually engineering proteins and building an original base DNA sequence of our own making and creating the cell to run it from scratch.

    At which point our machine overlords will take care of the rest. :P

    --
    "If I were bound by all laws everywhere I'm sure I would have committed a capital crime somewhere."
  8. Re:Inteligent design by iamacat · · Score: 4, Funny

    No, it would be an argument that a group of lab researchers are Gods for this particular bacteria.

  9. Sounds Good, But.... by arollo · · Score: 2, Funny

    When do I get to start playing God from the comfort of my own home?

  10. Re:Penrose by Cyberax · · Score: 3, Interesting

    Penrose was probably smocking crack when he wrote this book.

    You definitely don't NEED quantum computers to reproduce intelligence. That's because IF cells contain quantum computers, then they must work in cycles: load initial data, process it, read data. Reading computation results stops quantum computer (collapses it to one state). Even Penrose admits that quantum computers can't work more than a fraction of second in a living cell.

    Quantum computers can be simulated by classical computers (they're computationally equivalent), so quantum computers are not NEEDED to simulate human mind.

    However, quantum computers might make good accelerators for neural processing (there are several publications on this).

  11. Re:Mutation by BiggerIsBetter · · Score: 3, Funny

    But I bet we could engineer a microbe to kill those first microbes.

    "No, that's the beautiful part. When wintertime rolls around, the gorillas simply freeze to death."

    --
    Forget thrust, drag, lift and weight. Airplanes fly because of money.
  12. They did something very different from a virus by wisebabo · · Score: 4, Insightful

    A virus (DNA or RNA) when injected into a cell utilizes the existing cellular machinery to make mass copies of its own genetic code, encase them in proteins that its genetic code has transcribed and explodes the cell to allow the newly created viral particles out. In a few cases (retroviruses) the virus becomes reverse transcripted into the cell's DNA and can stay there hidden (like HIV) for a long time, sometimes even reproducing with the cell (a possible source of "junk" DNA or even some cancers). Notice that a virus has far less than the minimum number of genes to create the cellular mechanisms for life let alone reproduction.

    Venter's group has taken a cell and replaced ALL of the original DNA with the newly introduced DNA. (I believe a virus replaces nothing, it merely adds its own genetic code). While the newly introduced DNA comes from another bacterium, there is no reason to think that the DNA from a completely "man-made" source couldn't be introduced instead. By introducing fewer and fewer genes, Venter (and others) hope to find the "minimum" number of genes needed to make a living creature.

    Once this minimal life is created is new, possibly never before seen in nature, genes can be introduced one at a time. Because these genes are added to a "clean" slate, their functionality and efficiency can be controlled and optimized. Kinda like a much more powerful version of the transgenic mice they use in research where they selectively eliminate just ONE gene from the mouse strain to see what its effect is. I believe they have strains for all/almost all the thousands of genes in mice so they can evaluate them for various genetic ailments, disease resistance and whatnot. (Harvard was the first to get a patent on the genetic code of one of these mice: the first patented life. Go Harvard!)

    Here instead of removing one gene from the entire set (to an admittedly MUCH more complex organism), Venter will be able to control ALL the genes in his bacteria. This will greatly reduce/eliminate unwanted interactions (because the "unneeded" genes have been eliminated) allowing R&D to go much more quickly. Thus the optimism on creating oil producing bacteria. (Please note that "unneeded" refers to our needs not the bacteria, we can make a bacteria that is alive but is utterly dependent on vital nutrients that "wild" bacteria make themselves. Since our bacteria is simpler, we will use it not the wild version.)