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Fructose As Culprit In the Obesity Epidemic

drewtheman writes "According to an interview with Dr. Robert Lustig, Professor of Pediatric Endocrinology from the University of California, San Francisco, fructose, once touted as diabetic-friendly because it doesn't raise insulin levels directly, could be a major culprit for the obesity epidemic, high blood pressure, and elevated blood levels of LDL in Americans and others worldwide as they adopt American-style diets. Fructose comprises 50% of table sugar and up to 90% of high-fructose corn syrup, both ingredients found in copious quantity in most American prepared foods."

5 of 821 comments (clear)

  1. Re:Thank ADM, Cargill and their lobbyists. by MaelstromX · · Score: 5, Informative

    You're right, the sugar quotas and corn subsidies raise prices (directly or indirectly) for almost all consumable items. The jury is still out on whether HFCS truly is tied to obesity (there are studies that go both ways, and TFA adds as far as I can tell nothing new to the debate), but there is absolutely no question that it kills us economically.

    Just check out this research study that estimates that subtracting the benefits of the quotas/subsidies from the costs (i.e. consumer/producer benefits of lower costs minus "oh but the poor farming corporations!") leaves the American economy almost billion dollars per year better off.

  2. Re:I gave up HFCS for new years... by hazem · · Score: 5, Informative

    Heinz finally makes an "organic" ketchup that uses cane sugar instead of HFCS for sweetener. It actually tastes a lot better - like I remember it tasting as a kid. I've also seen other brands of ketchup that use regular sugar as well.

    I personally gave up HFCS and MSG to the best of my ability about 9 months ago. I'm still too fat (probably all the beer I still drink) but I do feel much much better. That near continuous run-down feeling is gone now. So is that all to frequent feeling after lunch like a bad flu was coming (buzzing in my head, hot flash, sweating, tightness in the chest, congested feeling).

    I'm sure someone will respond saying there's no scientific proof that MSG and HFSC are bad for me and that I'm a fool for trying to not consume them. That's just fine... call me a fool. I feel better not eating them and that's reason enough - placebo effect or not.

  3. Summary of article by amyhughes · · Score: 5, Informative

    Clearly people aren't taking the time to read the article (I'm shocked), so here's a summary of the fructose info...

    Our consumption of fructose has gone from less than half a pound per year in 1970 to 56 pounds per year in 2003.

    high fructose corn syrup came on the market after it was invented in Japan in 1966, and started finding its way into American foods in 1975. In 1980 the soft drink companies started introducing it into soft drinks and you can actually trace the prevalence of childhood obesity, and the rise, to 1980 when this change was made.

    it's not the calories that are different it's the fact that the only organ in your body that can take up fructose is your liver. Glucose, the standard sugar, can be taken up by every organ in the body, only 20% of glucose load ends up at your liver. So let's take 120 calories of glucose, that's two slices of white bread as an example, only 24 of those 120 calories will be metabolised by the liver, the rest of it will be metabolised by your muscles, by your brain, by your kidneys, by your heart etc.. Now let's take 120 calories of orange juice. Same 120 calories but now 60 of those calories are going to be fructose because fructose is half of sucrose and sucrose is what's in orange juice. So it's going to be all the fructose, that's 60 calories, plus 20% of the glucose, so that's another 12 out of 60 -- so in other words 72 out of the 120 calories will hit the liver, three times the substrate as when it was just glucose alone.

    fructose [does] three things that are particularly bad in the liver. The first is this uric acid pathway that I just mentioned, the second is that fructose initiates what's known as de novo lipogenesis...Which is fat production...Excess fat production and so VLDL [the bad form of cholesterol], very low density lipoproteins end up being manufactured when you consume this large bolus of fructose in a way that glucose does not, and so that leads to dyslipidaemia.

    And then the last thing that fructose does in the liver is it initiates an enzyme called Junk one, ...and when you initiate Junk one what happens is that your insulin receptor in your liver stops working...that means your insulin levels all over your body have to rise.

    put all of this together and basically you've got a feed forward system of increased insulin, increased liver fat, liver deposition of fat, increased inflammation -- you end up with non-alcoholic fatty liver disease. You end up with your inability to see your leptin [**leptin tells your brain you are full**] and so you consume more fructose and you've now got a viscious cycle out of control.

    In fact fructose, because of the way it's metabolised, is actually damaging your liver the same way alcohol is. In fact it's the exact same pathway, in fact fructose is alcohol without the buzz.

  4. Sadly by aepervius · · Score: 5, Informative

    I took organic chemistry so I understand what the ingredient are (at least on the basic structural level) and can pronunce them very well ;).

    Anyway the argument is a bad one (and remind me of the argument of people saying "oh god they are adding chemicals in our food") If you took normal organic growing food and we told you the list of stuff inside it, you would not understand half of it, still that would not make it more or less dangerous. 2-oxo-L-threo-hexono-1,4- lactone-2,3-enediol is an example of it. Naturally I could call it L-ascorbate too. Or maybe vitamin C. The problem are not that people don't understand what the smallest ingredient part in ppm or milli% of their food composition is, the problem is that people ignore totally the composition of the main ingredient, like fat, and refuse to do sport, and eat a lot during the day way way more than is necessary for their activities, and not equilibrated. It is a LIFESTYLE problem. It ain't one signle factor but a combination of many. And no, the ingredient you can't pronunce without having being in university ain't the problem.

    --
    C. Sagan : A demon haunted world:
    http://www.amazon.com/gp/product/0345409469/
    visit randi.org
  5. Re:from the "no shit" dept. by badasscat · · Score: 5, Informative

    Actual carbonated soda is very rare; it's not that unusual to see even Coca Cola vending machines that don't actually sell cola.

    Carbonated soda is not "very rare". And Coca Cola machines without soda only exist when other Coca Cola machines *with* soda sit right next to them.

    Japanese vending machines almost always exist in multiple units - it's actually uncommon to see a single vending machine by itself. In the event that you *do*, that vending machine will *always* have at least one, and usually two or more flavors of carbonated soda. When vending machines are paired together, they have one particular kind of drink in each, so yes, of course you will only find carbonated drinks in one out of the four or five machines in any given spot. But they're always there.

    This is a typical single-unit Suntory machine installation:
    http://www.japonophile.com/wp-content/uploads/2004 -2006/jihanki.jpg

    And the same for Coke:
    http://z.about.com/d/gojapan/1/0/8/2/machine2.gif

    This is a more common multi-machine installation:
    http://www.tjf.or.jp/deai_korea/contents/teacher/m ini_en/pic_mini/life031.jpg

    (I know the url says "korea", but that's Japan. Here is the original page it's from.)

    It is true that Japan has much more variety of drink types in their vending machines than we do. But I disagree that their drinks are all that much healthier. Their vending machines contain drinks of the following types:

    a) Canned iced coffee - always sweetened
    b) Soda
    c) Beer
    d) Sweetened, processed juice drinks (their equivalent to "Sunny Delight")
    e) Iced tea (unsweetened)

    Of those, only tea is even remotely healthy and calorie-free. And it's true that it's usually available for those who want it. But then, diet soda is always available at vending machines here too; not as healthy as tea, but at least calorie-free and non-obesity forming. Most people choose something else, in both countries.

    Our problem is portion control. The standard bottle size in vending machines here is 20oz. A Japanese canned coffee is I think 7oz. Big difference. We're drinking almost three times the sugar in our sugar drinks as they are, just because we're drinking a lot more of it. (This extends beyond vending machines too; go to McDonald's there and the "large" drink is the same size as a "small" here.)

    Combined with the rest of their diet, which is a lot less fatty and rich in calories, and with a lot smaller portions, and of course they're in better shape. Though with the rise of fast food there, they're fattening up now just like we already have. (Most articles on this are a bit alarmist, IMO - it's still obvious that they're in pretty good shape, but obesity rates are rising.)

    It's really not rocket science why we're all getting fat. Too many calories, too big portions. It drives me crazy how people read stuff like "fructose makes you fat!" and think they can just cut out fructose and lose weight. Meanwhile, they're still eating double quarter pounders with cheese, a large fries and two apple pies for lunch and wondering why they're still getting fat. The culprit to gaining weight is calories. That's it. Simple laws of physics. All of these foods that supposedly "cause" obesity do so because they are high in calories and low in nutrients. That includes fructose. The bottom line is you need to control your calorie intake, which means both controlling the types of food you eat as well as the amounts.