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Mitochondria and the Prevention of Death

H_Fisher writes "Research into mitochondria — small structures within a cell that have their own DNA — suggests that they may be a cause of cellular death, according to Newsweek. The article The Science of Death: Reviving the Dead reports on people who have recovered from sudden death due to cardiac arrest through the use of medically induced hypothermia. The cooling process may help stop the death of brain and heart cells initiated by the mitochondria once they are deprived of oxygen. The article goes on to probe delicately at the question of where a person's personality 'is' between death and later revival, and describes several ongoing scientific studies of near-death experiences."

5 of 453 comments (clear)

  1. Been there, done that. by RiffRafff · · Score: 5, Interesting

    I was diagnosed with "sick sinus syndrome." Well, not until I had basically died a few times. The electrical impulses that cause the heart to fire, ceased. I flat-lined, and was essentially "dead." The first few times (twice at home, 2 or 3 times at the hospital) I came back on my own. There was no "where am I?" questions upon regaining consciousness; I knew where I was, and I knew _something_ had happened, but I didn't know what. It wasn't until the last "episode," after they had attached a heart monitor with the little sticky-pads that the doctors actually knew, for sure, that I was flat-lining. They immediately ran a catheter up my groin, into my heart, and attached to an external pace-maker. A day later they implanted a pace-maker. Now, almost three years later, the pace-maker's computer says it has never "paced." In other words, I haven't really needed it. :-/

    My point is this: when I was "dead," I never "left my body," I never saw myself and the doctors in the hospital from "above," I never experienced anything. It was like a light-switch was simply flipped. I was just gone. No angels, no bright light, nothing. So. My advice, for what it's worth, is that you should do whatever you need to do. Whatever you need to accomplish. If my experience is any indication, there is no second chance. Do it now. Don't expect anything else after you're gone. When you're gone, you're gone. There appears to be nothing else. And while that may not be what you wanted to hear, that was my reality.

    Don't live your life in fear of death, but don't take anything for granted, either. As Warren Zevon said, "enjoy every sandwich."

    (Of course, Zevon also said, "I think I made a tactical error by not going to the doctor earlier." So don't do that.)

    --
    "I might have made a tactical error in not going to a physician for 20 years." -- Warren Zevon
    1. Re:Been there, done that. by Nefarious+Wheel · · Score: 4, Interesting
      I never saw myself and the doctors in the hospital from above...

      Well, I did. 11 years old, skull fracture from little league game (I was pitching, before the hard hat rule (which I was told I instigated)). No pre-knowledge or exposure to such states, or even the concept of mortality -- never a church goer. Genuine OOB perception, howling winds, players gathered around my supine body, sound of my dad calling me back (he was the team's manager). Followed by aphasia, surgery, long recovery.

      Nothing has ever been really spookey since. Meh, it's life. Do the next thing.

      --
      Do not mock my vision of impractical footwear
  2. I'm going to get railed by the mods for this... by jadin · · Score: 4, Interesting

    But this is precisely what the bible teaches about death. [note: no one is required to read this]

    Dead cannot think:
    Psalms 146:4 His breath goes forth, he returns to his earth; in that very day his thoughts perish.
    Ecclesiastes 9:5 For the living know that they shall die: but the dead know not any thing, neither have they any more a reward; for the memory of them is forgotten.

    It also says the soul dies at death:
    Ezekiel 18:4 Behold, all souls are mine; as the soul of the father, so also the soul of the son is mine: the soul that sinning, it shall die.
    Romans 5:12 Wherefore, as by one man sin entered into the world, and death by sin; and so death passed upon all men, for that all have sinned.

    Therefore the soul cannot think either. Aka no out of body experiences. Please note I'm not discussing heaven etc, just the state of the dead/soul.

    Hammer me down mods! [flamesuit="on"]

  3. Re:It's not exactly mysterious. by Dahamma · · Score: 5, Interesting

    Um, no....
    Sorry, I don't read "arguments" that begin with "um".


    I was so tempted just to reply "I don't read 'arguments' that begin with 'um' *or* 'sorry'" - but I decided that it was only slightly wittier than either of the originals, and witty they were not.

    I find it hilarious that an article mentioning (focused on is too strong - despite the title it was about 4 paragraphs) an extremely low level process (ie possible mitochondrial-related rapid apoptosis of neurons after oxygen short-term deprivation as a leading cause of death in cardiac arrest) has resulted in some moronic moral battle between "keep what you kill" and "meat is murder".

    Your argument is stupidly off-topic for this article. So, here are two fun trains of thought to get you guys back on track:

    1) Your mitochondria, after millions of years, have not realized that we can usually revive the rest of your body after 10 minutes of cardiac arrest. Don't we wish they could figure that out. Maybe we could rise above other base "evolutionary" traits as well and learn to be more ethical to other living beings. Meat is murder!

    2) Your mitochondria, after millions of years, are the result of an amazing evolutionary process likely descended from symbiotic prokaryotes that now constitute the major energy-producing components of our bodies. Thanks to said little helpers and many other evolutionary advantages, we can enjoy a higher standard of living, often grow over 6' tall with the plentiful supply of meat and dairy, and even entertain the luxury of pondering ethics and morality on slashdot. Meat, it's what's for dinner!

    Pick your pseudo-religious viewpoint, and go at it!

  4. Mitochondria *may* be a cause of cellular death? by tzot · · Score: 4, Interesting

    Why did I have the impression this is a well established fact? In addition, mitochondria not signalling the cell to die is the main reason that cancer cells don't die. It's many months now that research into dichloroacetate (DCA), which has been used for other purposes too, causes cancer-cell mitochondria to resume their operation and cause the cells to eventually die. See an example of a similar report.

    --
    I speak England very best