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Fish Poison Makes Hot Feel Cold and Vice Versa

SoyChemist writes "Ciguatoxin causes bizarre neurological symptoms including temperature reversal, a burning sensation, and an imaginary feeling of loose teeth. It is produced by algae and accumulates in the fatty flesh of tropical fish. While traveling to the tropics, a man from England ate some bad seafood that contained the unusual poison. His story, and the tale of some unfortunate sailors of an earlier age who suffered the same affliction, appeared in the current issue of Practical Neurology and was summarized on the Wired Science Blog. Both the Wired blog and the peer-reviewed journal neglected to mention that the potent neurotoxin has been made from scratch by organic chemists."

21 of 169 comments (clear)

  1. Paradoxical Dysaesthesia by die444die · · Score: 5, Funny

    paradoxical dysaesthesia is hot.

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    die444die
    1. Re:Paradoxical Dysaesthesia by Anonymous Coward · · Score: 4, Funny

      I get a burning sensation that it's cool!

  2. Cool! by sahar176 · · Score: 4, Funny

    Errr I mean...Hot!

  3. Hmm by evilviper · · Score: 5, Funny

    Ciguatoxin causes bizarre neurological symptoms including temperature reversal,

    Ah yes, good old XNOR poison... It's been a long time old friend.
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    1. Re:Hmm by MichaelSmith · · Score: 2, Funny

      Ah yes, good old XNOR poison

      Wouldn't that be NOT poison, or is that something else?

    2. Re:Hmm by I+Like+Pudding · · Score: 2, Funny

      Yes that's much closer to accurate, but you'll sound awfully stupid talking about "not poison".

      Yeah, and universities are going to be throwing honorary doctorates at you for talking about "XNOR poison". Then again, people tell me I see things only in black and white.
  4. About the journal this appeared in... by mdenham · · Score: 3, Funny

    ...would "Practical Neurology" be where you go if you're planning on having a drinking buddy do your brain surgery?

    1. Re:About the journal this appeared in... by sadangel · · Score: 4, Funny

      You insensitive clod! My drinking buddy *is* a world famous neurosurgeon!

  5. Re:Ciguatera is Common knowledge by ianalis · · Score: 5, Funny

    Share it... for mutually assured destruction :)

  6. Where to order? by clarkkent09 · · Score: 5, Funny

    The article failed to mention where can I get some of this poison? I need to cut down on my heating bill this winter.

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    Negative moral value of force outweighs the positive value of good intentions.
    1. Re:Where to order? by iknownuttin · · Score: 5, Funny
      The article failed to mention where can I get some of this poison? I need to cut down on my heating bill this winter.

      This is nice and everything, but I want know what the hell is my wife taking that makes her cold even when I'm sweating bullets!

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      I prefer Flambe as apposed flamebait.
  7. French? by youthoftoday · · Score: 3, Funny

    Fish poisson?

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    -1 not first post
    1. Re:French? by wboelen · · Score: 2, Funny

      Probably poison de poisson ;)

    2. Re:French? by Anonymous Coward · · Score: 1, Funny

      Un poisson empoisonné?

  8. oh my god by rpillala · · Score: 1, Funny

    Don't give the Bush administration any more ideas.

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    When the axe came to the forest, the trees said, "Look out - the handle was once one of us."
  9. LSD by nurb432 · · Score: 4, Funny

    Can do this too. And cheaper.

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    ---- Booth was a patriot ----
  10. USSR Fish Poison by Spookticus · · Score: 2, Funny

    In soviet russia, unusual fish poison that makes you feel hot as cold and cold as hot makes you feel hot as hot and cold as cold.

  11. Re:Nice curiosity, but what are the applications? by Jesus_666 · · Score: 4, Funny

    Awesome! I can't wait to read this on the back of deodorant spray cans:

    PoisonCorp(TM) Cool&Fresh(TM) dedorant will give your skin a cool and fresh feeling and will prevent sweating for up to twenty years.

    Known possible side effects include prickling of the skin, headaches, numbness, diarrhea, vomiting, dehydration, hyperthermia, hallucinations, lung failure, kidney failure, cardiac arrest, an atypical form of Parkinson's disease, coma and death.

    Not to be taken orally. Keep out of the reach of small children.

    Warning: PoisonCorp(TM) Cool&Fresh(TM) dedorant is known to build up in the groundwater and in animals. Any object that has been in direct contact with PoisonCorp(TM) Cool&Fresh(TM) dedorant at any point as well as the remains of persons, cremated or not, who have used PoisonCorp(TM) Cool&Fresh(TM) dedorant at any point may not be disposed of normally and must be handed over to the Environmental Protection Agency as per the Comprehensive Environmental Response, Compensation, and Liability Act ("Superfund Act") of 1980.

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    USE HOT GRITS WITH STATUE OF NATALIE PORTMAN (NAKED AND PETRIFIED)
  12. You're lucky by Anonymous Coward · · Score: 3, Funny

    "what the hell is my wife taking that makes her cold even when I'm sweating bullets!"

    Don't worry, in a few more years, she'll be feeling hot all the time. And she'll yell at you a lot. For no reason you're aware of.

    But on the plus side, all your hair will fall out, and your children will consider you stupid. Which, all things considered, you are.

  13. Re:Ciguatera is Common knowledge by BillX · · Score: 2, Funny

    And to avoid your friends thinking you're loony toony.

    Without sharing:
    "Oww, this fish is too piping hot to eat!" - You
    "Umm, are you going crazy? This dish is served cold." -Everyone Else

    With sharing:
    "Ack, this shit's too hot!" - You
    "Right on brother." - Everyone

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    Caveat Emptor is not a business model.
  14. Re:If sex feels bad... by delinear · · Score: 2, Funny

    Dude, I think he meant for her...