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Gene Found to Explain Repeated Mistakes

palegray.net writes "A December 6th article in Nature explores the relationship between a specific gene and those of us prone to repeatedly making the same mistakes. From the article: "Drug addicts, alcoholics and compulsive gamblers are known to be more likely than other people to have this genetic mutation ..." The gene results in the development of fewer D2 receptors in the brain, a condition which the study has shown leads to a lessened ability to learn from experience." So no complaining about dupes and typos: it's genetic!

13 of 299 comments (clear)

  1. Politics explained by El+Yanqui · · Score: 5, Funny

    Now I know why so many politicians get re-elected: Too few D2 receptors in the voting population.

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    1. Re:Politics explained by marcello_dl · · Score: 5, Funny

      Now I know why people upgrade their windows installation.

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  2. Just what we need by CRCulver · · Score: 5, Insightful

    When our society already has plenty of excuses to avoid personal responsibility (e.g. overdiagnosis of ADD to include kids who are just undiscipled), we give more ammunition to people who just don't want to try to get it right.

    1. Re:Just what we need by caution+live+frogs · · Score: 5, Insightful

      My biggest problem with this sort of science is that the general public usually gets everything about it wrong, thanks to bad reporting or poor understanding of science in general. Someone publishes an article stating that morph A of gene X is found more often than one would statistically expect in a number of persons with a specific condition, but when the public gets the results we get headlines screaming "OMFG TEH GHEY GENE FOUND" and that kind of crap, because it makes better press. Yes, there are conditions that can be caused by an aberration in a single gene (albinism, narcolepsy, etc.) but more often than not genes that control complex behaviors require multiple interactions between multiple genes; until proven otherwise you should always understand that publication of a finding like this is indicitave of a contributing factor, not a causal factor, for a given condition.

      Trust me. I do neuroscience for a living. When you're preparing the publication for submission, you always work your hardest to ensure that everything is accurate and properly phrased to be crystal clear about the limitations and drawbacks of the findings, only to have a reporter read nothing more than the abstract and get everything wrong. Don't blame the societal excuses on the scientists. People inclined to take the easy way out don't end up with PhDs, research careers, and articles in Nature.

    2. Re:Just what we need by Lemmy+Caution · · Score: 5, Insightful

      We already know that a lot of bad decisions are motivated by other physiological factors - adolescent "testosterone poisioning", PMS, dementia, etc. The fact that cognition has a material basis puts us in a place beyond either "excuses" or simple "suck it up" volitionalism. Each of us is, ultimately and existentially, "responsible" for ourselves. Yet much of our behavior and attitudes are still formed by factors out of our control, and there is no one I know who doesn't have thoughts, behaviors, and emotions which baffle them.

      Knowing the roots of these behaviors gives us a way to short-circuit the negative ones.

    3. Re:Just what we need by Tablizer · · Score: 5, Insightful

      When our society already has plenty of excuses to avoid personal responsibility (e.g. overdiagnosis of ADD to include kids who are just undiscipled),

      I think the problem is that humans on average are not designed to sit still for hours at little desks and move little symbols on flat bleached trees. A "problem child" may have been a brilliant hunter in an earlier era. I've seen families where one kid is almost an angel and the other from the same parents is a hyper mess. Whips and chains may work in the short term, but create a disturbed personality later in life.

  3. Interesting... by R2.0 · · Score: 5, Interesting

    I know a recovering alcoholic pretty well, and one of her pronounced traits is repeatedly doing the same things that she knows she shouldnt. Keep in mind that the phrase "Insanity is doing the same action over and over again and expecting a different result" comes from AA.

    Oddly enough, it only became really pronounced AFTER she stopped drinking - gene activation?

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  4. More than one way to Rome. by Trackster · · Score: 5, Insightful
    I think it's interesting that we are so easily convinced that genes control every little detail of our lives. Just because they find a gene that, when modified, affects this trait or that trait; we assume that's all there is to it. It's not. Playing with the genes may be _one_ way to get a certain result. However, it is _not the only_ way to get that same result. Anyone who knows the smallest bit about psychology and sociology know there are many ways to consistantly produce children (and by extension, adults) who repeatedly make mistakes. Heck, even physical injuries to the brain can produce certain behaviors.

    The road called "genes" isn't the only one that can take you to Rome. There are plenty of others. If life was like a golf green, genes would be the contour and speed of the green. Learning, society and environment would be the skill of the golfer, the putter, the wind, etc.

  5. I guess this explains ... by LaughingCoder · · Score: 5, Funny

    why I keep coming back to Slashdot!

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  6. Re:Now, for the most useful one by j-pimp · · Score: 5, Insightful

    This American disdain for politicians is perplexing. You claim to be so proud of your democracy. And yet you despise the people who personify and work for that democracy?

    American's hate all forms of government. We just hate ours the least. I doubt hating our government officials is a uniquely American phenomenon either. Perhaps our two party system makes it a bit more pronounced, but I find it hard to believe that no other country shows disdain for its leaders. Also hating ones leaders fits well into the belief that government is a necessary evil.

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  7. Isn't this backwards? by Fractal+Dice · · Score: 5, Interesting

    Isn't addiction the result of the brain learning too well that getting a certain stimulus triggers the pleasure/reward sensation? It's only a "mistake" when the stimulus turns out to be a false positive. The same "addicted" reaction to a drug that short-circuits the reward sensation might cause a person to acquire and maintain very good habits for needed nutrients or acquiring resources. It's a tradeoff between locking in behaviors that consistently produce rewards and the risk that you are locking in slowly self-destructive behaviors that only seemed to be a reward. A person who can break addictions easily may also tend to randomly stop doing useful, rewarding things.

  8. Re:Now, for the most useful one by QuickFox · · Score: 5, Interesting

    You trust your politicians? Of course not. Quite the contrary. For instance here in Sweden there have recently been several scandals with politicians not paying their taxes. We expect them to be selfish, and adapt our systems in such ways that their selfishness will work in our interest.

    For example, here in Sweden the members of the government, the ministers, have no right to give orders to authorities. Ministers decide about policy, and are expressly forbidden from meddling in the day-to-day matters of the authorities. That's to limit the influence of the power-hungry. The only exception is when an authority asks for a policy decision, and also some exceptional authorities such as the one that manages embassies and foreign affairs.

    This arrangement complicated matters a lot when a Swede was released from Guantanamo. The US demanded guarantees from the Swedish government that he would be supervised. Since the government is expressly forbidden from giving any such orders they couldn't give any such guarantees.

    It would make more sense for you Americans to simply expect your politicians to be selfish like everybody, and not despise them for that, and instead despise your system if it doesn't provide suitable checks and balances. Which I think it doesn't.
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  9. Re:Now, for the most useful one by fyngyrz · · Score: 5, Insightful

    It would make more sense for you Americans to simply expect your politicians to be selfish like everybody, and not despise them for that, and instead despise your system if it doesn't provide suitable checks and balances. Which I think it doesn't.

    +1 insightful, buddy. But the average American confuses the system with the nation. Despise the system? Then you're being unpatriotic. Another built-in design problem is that as you say, we should change the system so that the politicians have checks and balances. But we can't do that; only the politicians can. This is a deep and serious design flaw.

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