'Mind Doping' Becoming More Common

runamock writes "The Los Angeles Times is running a story on the growing use of 'mind drugs': 'Forget sports doping. The next frontier is brain doping. ... Despite the potential side effects, academics, classical musicians, corporate executives, students and even professional poker players have embraced the drugs to clarify their minds, improve their concentration or control their emotions. Unlike the anabolic steroids, human growth hormone and blood-oxygen boosters that plague athletic competitions, the brain drugs haven't provoked similar outrage. People who take them say the drugs aren't giving them an unfair advantage but merely allow them to make the most of their hard-earned skills.'" There's an interesting comment on this topic in Fresh Air's top cultural trends of 2007 broadcast.

Comments

Awesome

[chuck]

Did anyone else RTFA just to see what they should be taking to enhance their brain?

Re:Flashback!

[ehrichweiss]

"Well yeah, hallucinogens aren't really what they're suggesting here, I'd hope."

Funny you should say that. SOME hallucinogens behave like smart drugs at lower doses. LSD and mushrooms come to mind. LSD becomes a smart drug at 10% of the "psychedelic dosage" and behaves like it's cousin, Hydergine. Mushrooms start acting as an aphrodisiac at about 25% of the psychoactive dosage. Doesn't help me since the psychoactive dose puts my wife straight into sleepy/tired-land for the most part.

Re:Doesn't impact entertainment and ignorance

[aminorex]

You assume people care about the use of steroids by athletes. I don't think they do. As far as I can tell, only sports media and athletes care. Athletes care because they don't want to have to take dangerous drugs to stay competitive.

I take piracetam, vinpocetine, adrafinil, and methylphenidate. Of course it gives me an "unfair advantage". That's why I take them. It also benefits society, because it makes me orders of magnitude more productive as an engineer and a scientist that I would be otherwise. It benefits my family, various people in need in my community, and the many children in third-world nations that I can support because my income is freaking enormous. If I were good at something more lucrative than what I do, I might feel less pressure to enhance my performance, but I doubt it. With power (to produce income) comes responsibility (to distribute income).

Be Precise

[DynaSoar]

The article is about using psychotropics like amphetamines and methylphenidate (Ritalin) to "improve" brain power. In the short term they do. Then they bring on rebound effects like chronic depression. Continuing after that stresses the dopamine system (that these force to work harder) and can bring on Parkinson's. The Alzheimer's drug does the same, but they consider the long term drawbacks to be less than the immediate benefit. Using these drugs for the purpose stated in TFA is called "off-label use". This (mis-)use has been going on since the first stimulants (cocaine among them) became available over a century ago. These are performance enhancers, not true cognitive enhancers. The distinction is important, and there but buried in TFA.

From TFA:
> "Whatever company comes out with the first memory pill is going to put Viagra to shame," said University of Pennsylvania bioethicist Paul Root Wolpe.

The first company to come out with a memory pill (a true cognitive enhancer) was Sandoz of Switzerland. The name is Hydergine. The person who discovered it was Albert Hoffman. If he hadn't also discovered LSD and become (in)famous for that, he'd probably been nominated for a Nobel for Hydergine (and a bucket full of other highly useful drugs of his day). He mentioned he takes Hydergine 4 or 5 times a day -- at his 100th birthday party.

There have been many such drugs (nootropics; noh'-oh-troh''-pics) created since then. All of them are owned by companies that are owned by people not from the U.S. and so no U.S. companies can make profit from them. Thus, the FDA won't approve them, and pretend they don't exist. As evidence I point to recent Nobel recipient Eric Kandel (for his work on the dopamine system) who claimed he'd use his award money to create the first cognitive enhancing drug (nootropic), essentially publicly and purposefully ignoring Hoffman's discovery and the subsequent inventions.

On my way to a PhD in neuroscience, I got a master's in healthcare administration. I learned way too much about the FDA and big pharma to ever be comfortable with them again. The above statement is only one reason for that. An excuse given for not approving it is that it can cause one to become dizzy if they stand up fast. In other words, it's an effective anti-hypertensive -- it lowers blood pressure. That's more a benefit than a drawback, and is more harmless than the "acceptable" side effects from recent drugs being advertised. Hydergine and the other nootropics have far fewer negative side effects than most drugs and virtually no interaction with any other drugs, and have beneficial side effects besides. These are approved in part by the FDA, but only for advanced brain degenerative diseases, where their benefit is fairly negligible and unrecognizable. Use by those without such disease is not approved, and actively discouraged.

The good news is that due to the 1989 AIDS drug law, one can import from overseas 90 days worth at a time of any drug approved there for the on-label use. The bad news is that the USPS will try to confiscate any drugs coming from outside the US -- even those allowed by the 1989 AIDS law. This is due to pressure from the FDA, the corporate welfare office for big pharma.

I myself took Hydergine and Nootropil for 2 years, instead of the levodopa prescribed for Parkinson's. After that I no longer needed the levodopa (and still don't, a decade later), which itself has a rebound effect, causing permanent and progressive degeneration of motor control. If it weren't for these nootropics I probably would never have been able to finish my PhD. They cost me about $150 per 90 days, sent from Portugal. I consider that to be the best value for money spent in my entire life.