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Identical Twins Not Identical After All

Hugh Pickens writes "Contrary to previous beliefs, identical twins are not genetically identical. Researchers studied 19 pairs of monozygotic, or identical, twins and found differences in copy number variation in DNA which occurs when a set of coding letters in DNA are missing, or when extra copies of segments of DNA are produced. In most cases, variation in the number of copies likely has no impact on health or development but in others, it may be one factor in the likelihood of developing a disease (pdf). "Those differences may point the way to better understanding of genetic diseases when we study so-called discordant monozygotic twins....a pair of twins where one twin has a disorder and the other does not," says Carl Bruder, Ph.D. "If twin A develops Parkinson's and twin B does not, the region of their genome where they show differences is a target for further investigation to discover the basic genetic underpinnings of the disease.""

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  1. That was known for quite a while by bogd · · Score: 5, Informative

    I remember that during medical school (maybe 7 or 8 years ago) we were told that while identical twins have extremely similar DNA to each other, that DNA is not 100% identical. Maybe 98 or 99% (more than any other two individuals on this planet), but not 100%. So while this is an interesting research, it hardly qualifies as "news"...