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Antidepressants Work No Better Than a Placebo

Matthew Whalley writes "Researchers got hold of published and unpublished data from drug companies regarding the effectiveness of the most common antidepressant drugs. Previously, when meta-analyses have been conducted on only the published data, the drugs were shown to have a clinically significant effect. However, when the unpublished data is taken into account the difference between the effects of drug and placebo becomes clinically meaningless — just a 1 or 2 point difference on a 30-point depression rating scale — except for the most severely depressed patients. Doctors do not recommend that patients come off antidepressant drugs without support, but this study is likely to lead to a rethink regarding how the drugs are licensed and prescribed."

3 of 674 comments (clear)

  1. (SIGH) that figures by 192939495969798999 · · Score: 4, Funny

    (SIGH) nothing ever works, its hopeless!

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  2. Re:This just in! by Brian+Gordon · · Score: 4, Funny

    What? It's a placebo? AAH DON'T TELL ME!

    *plugs fingers in ears*
    la la la la la

  3. Re:Further evidence... by The+Grassy+Knoll · · Score: 4, Funny

    >consumers would tend to evaluate a widget more favorably if they had paid more money for it.

    Pah. Does every Slashdot comment need an Apple angle?

    .

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    They will never know the simple pleasure of a monkey knife fight