Alligator Blood May Be Source of New Antibiotics

esocid writes "Biochemists from McNeese State University have described how proteins in gator blood may provide a source of powerful new antibiotics to help fight infections associated with diabetic ulcers and severe burns. This new class of drug could also crack so-called 'superbugs' that are resistant to conventional medication. Previous studies have showed alligators have an unusually strong immune system; unlike humans, alligator immune systems can defend against microorganisms such as fungi, viruses, and bacteria without having prior exposure to them. Scientists believe that this is an evolutionary adaptation to promote quick wound healing, as alligators are often injured during fierce territorial battles."

Comments

Re:Maybe because you have read about it before:

[krayzkrok]

Yes, that's the research I was involved in. We actually first discovered this way back in 1999! We tested serum activity (and lysed leucocytes) in Australian saltwater crocodiles and later in 2002 in Australian freshwater crocodiles. We called this antimicrobial peptide "crocodillin". The work from 2005 comes from a project I did with Mark Merchant on saltwater crocs where we tried to learn more about the antimicrobial and antiviral activity. This latest media release is essential the same as the previous work, except this time with American alligators because Mark has more of them in the backyard than he does saltwater crocs. Adam

Re:I guess what's old is new again.

[krayzkrok]

I made the initial discovery with saltwater crocodiles back in 1999, and my colleague Dr Gill Diamond named the peptide "crocodillin". So this is really a decade old now!

http://news.bbc.co.uk/2/hi/science/nature/680840.stm

Adam Britton