Blender 2.46 Released
The Penguin Man writes to mention the latest release of Blender, the popular open-source 3D graphics suite was officially launched today. You can download it from Blender.org. The culmination of half a year's work has resulted in many new features including a new particle system, approximate AO, the new cloth simulation system, and much more!
If you want, you could wait for Blender 2.50. They plan to completely rewrite the interface which will allow users the power to create their own if needed.
Honestly, I've never found the interface too much of a problem. Sure, it's different but it has been designed well (mainly for speed). A 3D suite isn't something that's really meant to simple anyway.
Subject says it all.