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Ancestry Surprises From New Genetics Analysis Method

An anonymous reader commends a recently published study involving a new way to analyze genetic variation in human populations (full article published in PLOS Genetics): "[S]cientists from Ireland, the UK and the US analysed 2,540 genetic markers in the DNA of almost 1,000 people from around the world whose genetic material had been collected by the Human Genome Diversity Project. The results include a number of surprises... the Yakut people of northern Siberia were found to have received a significant genetic contribution from the population of the Orkney Islands, which lie off the coast of Scotland... there must have been a period of gene flow from northern Europe to east Asia. The study also shed light on the peopling of the Americas, as the results suggest that the native populations of north and south America have different origins."

37 of 223 comments (clear)

  1. The N./S. America thing has been controversial by Anonymous Coward · · Score: 5, Interesting

    A lot of people didn't want to give up on the idea that the arctic bridge was the only way people got to the Americas, when it made much more sense that some people could've traveled the ocean to settle here.

  2. Wow! by mrbluze · · Score: 5, Funny

    there must have been a period of gene flow from northern Europe to east Asia. That was one helluva Khyber toss!
    --
    Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
  3. Confirmation of previous theories by steelfood · · Score: 5, Informative

    Well, there's anthropological evidence that there were several migrations from Asia to the Americas, namely, two island-hopping sea routes and one over the land bridge in the north. This just sort of confirms this idea.

    --
    "If a nation expects to be ignorant and free in a state of civilization, it expects what never was and never will be."
    1. Re:Confirmation of previous theories by William+Robinson · · Score: 3, Funny

      I knew my boss had something to do with cannibals.

  4. Maps of human travel on earth by Frekko · · Score: 3, Interesting

    This story sparked my interest so I searched for a while on the internet to find some maps of what the world looked like back in the ages and where evidence of people has been found linked with DNA evidence of how people actually have moved.
    I sadly came up with nothing... anyone who knows where to find anything like this?

    1. Re:Maps of human travel on earth by ya+really · · Score: 5, Informative

      Probably one of the best sources I can think of off the top of my head is the book, Guns Germs and Steel. The book gives a great in depth look at the origins of man, and the crops/domesticated animals we eat as well as lots of maps showing movements through the ages. It's a pretty long read though, but well worth it. The book also goes well into why the decendants of those from Europe and Asia control the world today and not those in Africa, North America or Oceana.

    2. Re:Maps of human travel on earth by ResidntGeek · · Score: 3, Informative

      Have you checked out Movie S1 in the current article? It's an animation of how people moved based on DNA evidence.

      Also, the world didn't look any different geologically, if that's what you mean by "what the world looked like back in the ages". The timescales of human migrations are far smaller than those of geological processes.

      --
      ResidntGeek
    3. Re:Maps of human travel on earth by BungaDunga · · Score: 4, Informative

      Except for the Bering land bridge. That's a function of sea level, but the world did look quite a bit different. Lots more ice around, less water.

    4. Re:Maps of human travel on earth by digitig · · Score: 5, Interesting

      The theory I am most familiar with is that it's to do with land distribution and early technology. Early technology was largely plant and animal based. That technology spread easily east-west because of broadly similar climate, but didn't spread well north-south because of climate changes. Eurasia provided a massive east-west area, but Africa, India, Polynesia and so on were relaively isolated in the east-west direction. That means that technology advanced faster in the north than in the south. Add in the general human tendancy of the powerful oppressing the weak and hey, presto! White (and Yellow) colonialism. No racial causes, just the luck of the draw in who was in the right place at the right time.

      --
      Quidnam Latine loqui modo coepi?
    5. Re:Maps of human travel on earth by corbettw · · Score: 3, Interesting

      I've always suspected that one of the reasons for Europe and the Middle East's preeminence through much of history was the Mediterranean Sea and the easy trade routes provided by it. The Phoenicians, Greeks, Carthaginians, and Romans all made great use of the sea in building their empires; I doubt any of them would've been half as successful without it.

      --
      God invented whiskey so the Irish would not rule the world.
  5. Polynesians by Bananatree3 · · Score: 4, Interesting
    If people reached Easter Island, which is almost off the coast of South America, what would have stopped Polynesian explorers from traveling all the way to Chile? It seems statistically low that explorers would have been able to hit a tiny island off the coast of S.A. and not have at least had one or two exploratory parties hit the coast.

    This isn't to say Polynesians were the first to South America, as Easter Island was populated around 2000 years ago while S.A. was populated many thousands of more years before that. However, it seems likely that there might have been genetic mixing between Polynesians and South American coastal tribes.

    1. Re:Polynesians by hengist · · Score: 4, Informative

      > If people reached Easter Island, which is almost off the coast of South America, what would have stopped Polynesian explorers from
      > traveling all the way to Chile?

      As I understand it, current thinking is that polynesians did make it to South America, which is where they got gourds and sweet potatoes from. Then, they turned around and followed the prevailing winds home.

      Thor Heyerdahl thought that polynesians came from South America and followed the prevailing winds in migrating west. But, genetic evidence proves that they come from Taiwain. The current theory is that they explored into the wind because it gave them a free trip home if they didn't find anything.

    2. Re:Polynesians by DerangedAlchemist · · Score: 5, Interesting

      Recently, ancient chicken DNA from South America was found to be most closely related to Polynesian chickens. I believe it was specifically chickens from Tonga, which is close to Easter Island. Previously, there was some dispute because carbon dating of the oldest chicken skeletons suggested they were a couple of hundred years older than the Spanish had arrived.
      So it probably did occur something like you suggest, even if the human populations were wiped out by local tribes and show no genetic mixing.

    3. Re:Polynesians by maglor_83 · · Score: 5, Funny

      carbon dating of the oldest chicken skeletons suggested they were a couple of hundred years older than the Spanish had arrived. You don't happen to know the results of carbon dating of the oldest chicken eggs do you? We might be able to answer the question once and for all!

  6. Re:It's a smaller world up there... by Harmonious+Botch · · Score: 3, Insightful

    ...and fuck a lot when we get there.

  7. Re:Where is this going? by mrbluze · · Score: 3, Interesting

    What if at some point it became obvious that certain populations were (objectively) superior to others, in terms of predisposition toward diseases, etc.

    The end of WWII supposedly brought an end to eugenics in Germany, but it was, even then, thriving in the English speaking world and continues to do so.

    The weakness of our civilization has become a lack of any moral vigor. Pretty much every time there is protest on moral grounds it is trivialized by the media and the whole thing is treated like a sport between nay-sayers and scientists.

    It's a weakness because it breeds distrust and fear in the community. if we don't come up with/maintain some kind of moral integrity in our scientific community, we will be overrun by groups who will impose an extreme opposite on us. And yeah, you're right, someone will come up with a logical but crazy conclusion and we'll have another wave of white-coat slaughter happening.

    --
    Do it yourself, because no one else will do it yourself. [beta blockade 10-17 Feb]
  8. So "Native Americans" were invaders? by whoever57 · · Score: 3, Insightful
    From the summary:

    In their proposed scenario, the population which first colonised North East Asia also crossed the Bering Strait and eventually made it to South America. This population was subsequently replaced by a population more closely related to modern East Asians. These people also successfully crossed the Bering Strait and contributed to the ancestry of the native North Americans.
    So what does this mean for Native Americans? They were aggressive immigrants who displaced the original population?
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    1. Re:So "Native Americans" were invaders? by kripkenstein · · Score: 5, Insightful

      So what does this mean for Native Americans? They were aggressive immigrants who displaced the original population? Essentially all human populations are/were aggressive invaders at some point. See Jared Diamond's writings, for example, about how the Bantu came to occupy most of Africa, how the Han Chinese did the same for China, etc., etc.

      We see things as they are right now, and just presume that the clock was frozen before the last few centuries. So, we see black people in Africa and Chinese people in China and assume they were always there. They weren't, they displaced someone to get there. It's just been forgotten.

      Not that this makes any of it 'right' or 'justified', nor does it make it 'wrong' or 'unjustified'. These are the facts. Make of them what you will.
  9. But other studies have shown different results. by Jane+Q.+Public · · Score: 3, Informative

    Extensive studies of mitochondrial DNA have pretty much confirmed migrations from east Asia to northwest America, then down south. There were, of course, more than one wave of such migrations. I doubt very much that the natives of north and south america "have different origins", because that would contradict well-established evidence that this is not so. However, they could certainly have a different mix of dna mutations showing various mixes from different areas.

    1. Re:But other studies have shown different results. by aibob · · Score: 5, Interesting

      Remember that there is a difference between using mitochondrial DNA (the studies you cited) and autosomal DNA (this study). With mitochondrial DNA, the only information that you get is along the maternal line, so you're missing a lot of the data. Looking back 20 generations, for example, you're only looking at one ancestor out of about a million. It would be possible for two groups to come over but only one be reflected in the maternal line.

  10. It doesn't say agressive by Moraelin · · Score: 4, Insightful

    Well, primitive tribes _were_ extremely aggressive, and did fight all the time.

    On the other hand "contributed to the ancestry of the native North Americans" implies interbreeding, rather than genocide. I.e., they fucked their way across two continents.

    It's not exactly surprising, though. A staple of tribal warfare, and it even lasted well into Iron Age in Greece for example, was raiding for another tribe's women, not just their food.

    Life expectancy for women was rather disproportionately lower than for men in primitive societieties, and for men it wasn't as high as to reach andropause first. So eventually a lot of still able men were left with the prospect of either finding another woman somehow, or playing with Miss Rosy Palm for the next 5 to 10 years. Meanwhile the next tribe had plenty of women. Are you thinking what I'm thinking, Pinky?

    Of course then the next tribe had an acute shortage of women, so the cycle of violence continued.

    So I'm saying that interbreeding would have been inevitable. When the newly arrived East Asians won a raid, they got some women from the previous populations, when they lost one, the opposite would happen.

    --
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  11. Re:RTFA by HadouKen24 · · Score: 5, Interesting

    You'd be wrong there.

    Depends on what period of history and what area you're talking about, actually.

    There's evidence of Jewish presence in China as early as the 7th century. There were reports in the 9th century of Christian, Muslims, and Jews killed in a massacre in the 9th century. And Marco Polo reported encountering Jews in China in the 13th century. They lived mostly in Kaifeng, where a synagogue was built in the 11th century.

    However, it wasn't until the 15th century that Jews in China had much recognition by the local government. In 1421, Jews were finally allowed to take the civil service test. The population in Kaifeng was discovered by European Christians in the 17th century, who used their version of the Torah to crosscheck it against the versions being used in Europe. They were identical.

    So... yeah. Not many Jews, but there are signs dating back to the 7th century that Jews were present.


    'Course, that's not nearly early enough to match up with Mormon scripture.

  12. First born child by syousef · · Score: 4, Funny

    Yakut people of northern Siberia were found to have received a significant genetic contribution from the population of the Orkney Islands, which lie off the coast of Scotland.

    My wife's pregnant with her first. We had a girl's name picked but were having hell trying to find a boy's name. She was having trouble so we had another ultrasound. We now KNOW it's a boy. I think this story has settled it. I'll be naming my first born Vladamir McHaggis. Being beaten up will build the boy's character.

    --
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    1. Re:First born child by hcdejong · · Score: 5, Funny

      I'll be naming my first born ... Being beaten up will build the boy's character. Ah, the Johnny Cash school of child rearing.
  13. Re:Where is this going? by rrohbeck · · Score: 3, Interesting

    Yes, Eugenics has a bad rap because of the way it used to be done forcibly in Nazi Germany, the US and other places.
    But what's wrong with it if it's done in an ethically responsible way? [Prospective] parents have access to genetic testing/counseling if there's known risks like hereditary diseases, and embryos can be tested and aborted if they have severe [genetic] defects. If a couple has significant genetic defects they can choose to adopt. That's eugenics, pure and simple. What's wrong with that?
    And don't start with a slippery slope argument. It's up to legislation to set the proper limits and it's up to society to apply scientific results in the proper way. We are able to read the genome today, and it's getting cheaper and cheaper. Applied properly, this can be very beneficial. Applied badly, see Gattaca.

  14. Re:Where is this going? by Bastard+of+Subhumani · · Score: 4, Insightful

    Once you let a governmental organization have anything to do with it though, it becomes evil and must be stopped at all costs.
    What would you class as interfereing? Discouraging people from having defective children? Or subsidising healthcare for preventable, avoidable defects - thus encouraging them to do so?
    --
    Only three things are certain; death, taxes, and apocryphal quotations - Ben Franklin.
  15. There is sort of a mine buried in that... by patio11 · · Score: 4, Insightful

    Hint: its what happens right after "tested and".

    OK, so you don't agree with me about abortion. And you probably don't think that in 50 years people will think aborting one in three black children is 1920s eugenics, except with scaleability added.

    But lets talk about legislation. See, I don't think saying "If there is a problem, fix it with a law" is an adequate response to "Law consistently fails to solve some problems, for structural reasons". Take the abortion regime in the United States, for example. Ignore the moral dimension for the rest of this post -- you don't have to agree that abortion is bad, you just have to make objective judgements of when it is legally available and when it is not. As a statement of fact, the United States has one of the most permissive abortion regimes in the Western world. Yeah, really.

    Has the legal system in the United States hithertofore successfully discriminated between good reasons for abortions and bad reasons? No. Its set up so that it is essentially impossible to force that distinction into law. As a result, despite having a massive political movement dedicated to opposing abortion, and extraordinarily conservative attitudes about sex and abortion relative to peer nations such as many in Europe, the United States in actual practice prohibits far fewer abortions that peer nations in Europe do. (Really: take a look at the gestational limits in Europe. http://news.bbc.co.uk/2/hi/europe/6235557.stm That is 12 weeks in Belgium, Denmark, etc -- that limit would be and has been stricken as unconstitutionally restrictive in that noted liberal hotspot, Kansas.)

    There's a bunch of reasons for that. One is the particularized development of the US abortion regime through the courts. Another is that the current American political consensus is somewhere between "I really do not want to hear about this, ever" and "Well, certainly SOME fraction of abortions are justified, for terrible circumstances which I would never, ever inquire about in polite company". A third is that the primary providers of abortion, who theoretically would end up as expert decisionmakers for legal compliance, are a political movement dedicated to keeping abortion restriction free. As a result, the questions which could theoretically ferret out "good" abortions from "bad" abortions, if one believed that such distinctions existed, can't be legislated and don't get asked.

    The same will be true of eugenics.

    Would America be socially willing to ask prospective eugenics parents "Excuse me, heard about your problem, so sorry. By the way, was that problem 'Your child is 78% likely to be missing a limb' or 'Your child is 83% likely to be left-handed'"? (Presumably that would be "bad" eugenics, right?) No, we won't be -- egads, that would be a ghastly thing to ask someone, particularly someone who just lost a child because he was headless. So nobody will be asked anything, just like nobody is required to substantiate why they want an abortion.

    Would America be willing to impose a coercive state apparatus on eugenicists to ensure that some crazy 1920s-reject racist doesn't recommend 1/3 of black kids for termination? No. Heck, no need for a hypothetical here: we actually do terminate 1/3 of black kids, in the status quo. There is no national coercive apparatus monitoring abortion.

    Eugenics will be worth billions upon billions of dollars, with a well-funded lobby, like reproductive medicine is and like abortion is. Children with birth defects, and children with "birth defects" like being left-handed or not predisposed to being athletic or possibly being gay, do not typically have much campaign cash to spend. Which group do you think is going to win in the US political system?

  16. Re:Where is this going? by evilviper · · Score: 3, Insightful

    Yes, Eugenics has a bad rap because of the way it used to be done forcibly in Nazi Germany, the US and other places.

    Eugenics has a bad rap because it's been throughly disproven as complete pseudoscience.

    [Prospective] parents have access to genetic testing/counseling if there's known risks like hereditary diseases, and embryos can be tested and aborted if they have severe [genetic] defects.

    That's not eugenics... That's just genetic screening.

    Eugenics is the process of sterilizing "lesser" peoples, such as the poor, and non-white, because of the (false) theory that their offspring were doomed to be similarly intellectually handicapped, regardless of the amount of education they received. This is basically the same (racist) argument long used to suppress negros, being applied instead to poor "white trash" classes of people.

    On the (entirely separate) question of genetic screening, I would certainly discourage it. People's desires for their children, and culturally-influenced impression of what traits are "good" and "bad" are not necessarily correct. Some of the smartest people to ever have lived suffer from physical and mental defects, and it's currently impossible to know if their intelligence was in spite of, or perhaps because of that very handicap. If anything, I think modern history has proven that genetic diversity is a GOOD thing. Yet, people have proven to be irrational beings, by and large, and need to be protected from their own desire to establish a monoculture in selecting their offspring.

    What happens when everyone on the planet is selecting their unborn children for intelligence, only to find out that our current established theory of what genetic traits lead to intelligence turn out to be wrong, and the world is filled with a generation of mentally handicapped children?
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  17. Re:Open For Reinterpretation by FurtiveGlancer · · Score: 4, Insightful

    If it's science, it should ALWAYS be open for reinterpretation as more data is collected and as analysis techniques improve or are replaced with better procedures.

    IMHO, an open mind should be, well, open.

    --
    Invenio via vel creo
  18. Re:Most people in Taiwan are not "Taiwanese" by Oligonicella · · Score: 4, Insightful

    Context. It's called context. When you're talking thousands of years ago, it gives context to the term.

  19. Re:Where is this going? by Bastard+of+Subhumani · · Score: 4, Insightful

    What happens when everyone on the planet is selecting their unborn children for intelligence, only to find out that our current established theory of what genetic traits lead to intelligence turn out to be wrong, and the world is filled with a generation of mentally handicapped children?
    I'm looking at it right now.
    --
    Only three things are certain; death, taxes, and apocryphal quotations - Ben Franklin.
  20. Re:Where is this going? by Bastard+of+Subhumani · · Score: 3, Insightful

    Nice soundbite, but impractical.

    Take one common cause of genetic problems - inbreeding.

    Either you use force (making incest illegal) or you use force (tax money) to look after the resulting crop of web-footed 'tards.

    --
    Only three things are certain; death, taxes, and apocryphal quotations - Ben Franklin.
  21. Nations of Europe by eggspurt · · Score: 3, Interesting

    The movies they attach are not very good.

    I have some Python source code for doing similar things with the case of European nations on http://www.stat.columbia.edu/~cook/movabletype/archives/2007/06/animated_mds_co.html (there is an animated GIF there).

    A bit more discussion about my methodology is at http://www.stat.columbia.edu/~cook/movabletype/archives/2007/06/nations_of_euro.html

  22. Re:RTFA by notadoctor · · Score: 3, Informative

    I'm not trying to perpetuate a religious argument or anything, but I would just like to point out two or three things in response. First, map 34 in Figure 4 shows the Colombian people having some origin in the regions around Eastern Iran and Western India, not China. The Jewish nation was taken captive into Persia (modern Iran) circa 722 B.C. A couple of other contemporary invasions also sent descendants of Israel all over the old world. That is early enough to match Mormon scripture, though the migratory pattern doesn't match the scenario described in the book. Second, the Book of Mormon states the people described therein were of the tribe of Manasseh, not Judah. "Jew" only referred to their nationality, not their ethnicity. Third, most Jews in Israel today are descendants of the European Jews of the Diaspora rather than those present in the land of Palestine during the later Biblical periods.

  23. Re:silly by cheesybagel · · Score: 3, Interesting

    You are forgetting gunpowder guns, steel armor, and horses. Those improved the chances significantly. The fact that at least in Central America the natives were a bunch of bickering and warring tribes helped as well. Try reading about how Cortes invaded Tenochtitlan. If I was getting my place raided and my people enslaved to provide for live sacrifices, I would have joined the Spanish too. Besides, they may have got smallpox, but we got gonorrhea.

  24. Re:silly by DerangedAlchemist · · Score: 3, Informative

    Disease made all the difference. Europeans had gunpowder, gun, steel armor and horses over the Africans too, but Africa had it's own terrible diseases. The dominant population in Africa is still black. It's estimated that 80-95% of North American natives died from disease. For comparison, the black plague killed 30-50% of the population of Europe.

  25. Re:silly by Mr.+Slippery · · Score: 3, Informative

    there is no evidence at all that the Chinese made it to South America before the Europeans.

    There is some suggestive evidence: the Fu Sang legends, South American folktales about "people from the sea", old stone anchors found off the Pacific coast, certain artistic motifs found in both Chinese and South American art. Joseph Campbell spends a few pages on this idea in one of the essays in Flight of the Wild Gander, but I'm too lazy to dig up my copy at the moment. I don't mean to suggest that it's a well-established mainstream theory, but IMHO there're enough hints to call it a sensible possibility.

    quite able to defend themselves against a few Chinese ships

    Just because Columbus and Company got slavery and rapine on their minds the moment they arrived, doesn't mean previous visitors did.

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