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Stem Cells From Fat Create Beating Heart Cells

Amenacier writes "Melbourne scientists recently discovered that stem cells isolated from human fat could be made to turn into beating heart muscle cells when cultured with rat heart cells. This discovery may lead to the use of fat stem cells in repairing cardiac damage, or fixing such cardiac problems as holes in the heart. It is proposed that culturing the stem cells with rat heart cells allows them to differentiate into heart muscle through signals from the rat cells. In the future it may be possible to inject/transplant the stem cells into the damaged area and have them naturally differentiate into the type of cell required, with only the natural stimuli provided by surrounding cells, without any danger of rejection by the body. Quoting: 'The next step is to implant the human heart cells onto the damaged heart of a laboratory rat to see whether they repair the heart. Then they would be trialled in higher species such as sheep and pigs before human applications could be considered. Clinical application could be five years away ...'" The Age has a multimedia treatment (Flash) of the discovery.

8 of 198 comments (clear)

  1. Rat hearted overlords? by rubies · · Score: 5, Funny

    Nah. We've already got those.

    1. Re:Rat hearted overlords? by Rod+Beauvex · · Score: 5, Funny

      I ask that all rat lovers mod parent down for such an insult to rats everywhere.

    2. Re:Rat hearted overlords? by gnick · · Score: 5, Interesting

      I ask that all rat lovers mod parent down for such an insult to rats everywhere.

      Pretty much off-topic, so I've foregone my karmic bonus. Mods, please be gentle.

      Rats rock. Best pets I've had. They're clean, loyal, friendly, and low upkeep. Terrific. They've even potty-trainable with less that 1-month of effort - I used to let mine run loose and kept ramps up so that they could return to their cages to crap.
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      On-topic... If we can generate stem-cells applicable to human research trans-specially, who other than PETA would continue to object?

      --
      He's getting rather old, but he's a good mouse.
  2. Re:Oh the irony... by Barny · · Score: 5, Funny

    And we shall harvest them, oh yes the time of the great fat farm is at hand.

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    ...
    /me sighs
  3. Re:Better hope by acris · · Score: 5, Informative

    That McCain/Palin don't get elected if you want this kind of research to continue.

    no matter who gets elected in the USA, future research won't be effected by this. Unless said president decides to attack Australia. Please do more research next time before making off-hand comments about politics.

  4. Tuesday is my Fat-Heart group... by retech · · Score: 5, Funny

    So the plan was to get the entire world to bulk up and then sell their fat back to them as a means to save them...

    the first rule of stem cell research is you don't talk about stem cell research.

  5. Re:Better hope by Anonymous Coward · · Score: 5, Funny

    When "research" includes such things as "discovering that other nations exist," we are well and truly fucked.

  6. Re:Better hope by MPolo · · Score: 5, Informative

    Even more so, since this is not embryonic stem-cell research (to which McCain, Palin, and many other Christians object), but rather adult stem-cell research (to which only Jehovah's Witnesses and Christian Scientists object, as far as I know).

    Personally, I have yet to read of truly successful research with embryonic stem cells (because they are generally rejected by the recipient), whereas many large advances have been made with adult stem cells (since the donor and the recipient are the same person, rejection is eliminated) -- for men at least, pluripotent cells have been found in the testicles, so that any type of cell could be produced without having to use embryonic stem cells. I also recently saw a report about a person with congenital heart disease who was apparently cured by an injection of his own bone-marrow stem cells.

    So I suppose my question would be why the intellectual elites want to spend their research monies on embryonic stem-cell research that is more expensive, less successful, and morally questionable to a large sector of society, rather than on research in areas where successes keep coming, the cells are available without moral complications, and the costs are in general lower. A cynical person might think that it's all about getting drug patents and getting money out of the consumers and padding their own checkbooks...