First Whole Cancer Genome Sequenced

dooling writes "A paper detailing the sequencing of the first human cancer genome will be published in the 6 November 2008 issue of Nature. This is not only the first cancer genome published, it is the first female genome as well. You can read the paper's abstract, DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome, or the story in Science News. This issue of Nature also has articles on the sequencing of the first African and Asian genomes. The sequencing in all three articles was done using the Illumina Genome Analyzer, one of the massively parallel, next-generation genome sequencing platforms."

Comments

Two genomes from the same person

[jfengel]

The Science News article says that they sequenced both a cancer cell and a non-cancer cell from this woman. So we can specifically say "these are the bases that are different" and from there (with luck) to "this is the mutation that happened".

That should prove quite illuminating.