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Diet of Fast Food and Candy May Cause Alzheimer's

lurking_giant sends along a Reuters report on research out of Sweden indicating that a diet rich in fat, sugar, and cholesterol could increase the risk of Alzheimer's, at least in mice. "'On examining the brains of these mice, we found a chemical change not unlike that found in the Alzheimer brain,' [said] Susanne Akterin, a researcher at the Karolinska Institutet's Alzheimer's Disease Research Center... 'We now suspect that a high intake of fat and cholesterol in combination with genetic factors... can adversely affect several brain substances, which can be a contributory factor in the development of Alzheimer's.' ... These mice showed chemical changes in their brains, indicating an abnormal build-up of the protein tau as well as signs that cholesterol in food reduced levels of another protein called Arc involved in memory storage."

5 of 224 comments (clear)

  1. "Everything in moderation" by macraig · · Score: 3, Informative

    That's an ancient cliche but very relevant. Eating too much rock dust would cause cancer. So too would anything else consumed in a quantity that creates an imbalance.

  2. Re:Obvious? by wisty · · Score: 3, Informative

    Not a great idea. A lot of US agriculture industries have a lot of "government relations" clout. See Why Does a Salad Cost More Than a Big Mac?. Then we can talk about McDonalds, KFC, and Coca Cola.

  3. This just in! by forgoil · · Score: 4, Informative

    Living will kill you.

  4. Re:Obvious? by dgatwood · · Score: 3, Informative

    It is somewhat naive to claim that those things are "really, really, really bad for you", though. While it is clear that these can have significant negative side effects on weight in some portion of the population if consumed in excess, the fact that this does not occur across the population universally, however, means that one could argue that the consumption of these foods by people who do not exhibit extreme weight gain from them might actually be helpful, and that not consuming energy-rich foods may be starving those people's cells. Everyone's body has different nutritional needs in terms of calories, etc., and painting with too broad a brush does more harm than good when it comes to understanding the issues involved.

    For example, by some people's standards, caffeine is really, really bad for you. The same goes for alcohol. However, we now know that both of these substances decrease the risk of stroke and heart disease. Caffeine even decreases the risk of Alzheimer's and other neurological disorders. Following conventional wisdom and common sense to answer nutritional or medical questions frequently results in getting entirely the wrong answer.

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    Check out my sci-fi/humor trilogy at PatriotsBooks.

  5. Bad scientist! by durrr · · Score: 3, Informative

    The study is quite flawed, she might as well feed them a diet "rich in rat poison" and conclude that it's quite fatal for the critters.

    There are more studies needed, focusing on the separate compounds; is a diet rich in sugar bad? Is the sugar rich diet bad if the net caloric intake is low? Is the sugar rich diets bad when combined with nutritional supplements that cover the nutritional needs that sugar doesn't provide? Is a combination diet of sugar and fat worse or better than the single sugar or single fat ones? Is HDL cholesterol a equal factor as LDL cholesterol? In what manners do the mice metabolism change in the diets? Could these changes perhaps be blocked by medication, and if yes, will it prevent alzheimers?

    The study tells us what we already know, a diet of junk food is bad for you. However, most likely a diet of junk food will kill you trough some other pathway before you develop alzheimers.