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Cold Sore Virus May Be Alzheimer's Smoking Gun
Science Daily is reporting that the virus behind cold sores has been found to be a major cause of the insoluble protein plaques found in the brains of Alzheimer's disease sufferers. Researchers believe the herpes simplex virus is a significant factor in developing the debilitating disease and could be treated by antiviral agents such as acyclovir, which is already used to treat cold sores and other diseases caused by the herpes virus. Another future possibility is vaccination against the virus to prevent the development of Alzheimer's in the first place. The research was just published in the Journal of Pathology (abstract).
Alzheimers runs in families, which is particularly worrisome for me since I have it on both sides of my family. If it is caused by a virus, then why is it passed down in genes? Are some people more sucseptible to this virus, thus there is a gene for vulnerabilty to this virus, instead of a gene for Alzheimers??
Herpes Zoster and Herpes Simplex viruses are killed with a silver ion concentration of 16ppm or more. Just hold the solution in your mouth for ten minutes, then spit it out. There is no danger of Argyria since most is discarded and very little remains in your blood stream. Estimates are 4 parts per billion, which is far below the 2 grams generally recognized as required for Argyria to show. The little that does remain is eliminated in several days, so it is wise to keep taking the solution as a preventative measure.
The ions appear to work with the immune system much the same way as other trance elements are needed, like chromium, selenium, and so on. A deficiency of silver will make you more vulnerable to pathological infections, but these disappear as soon as the silver ions are absorbed into the blood stream.
Most of the solutions sold in health stores is 3 to 5 ppm, which is too weak to do much good. You need about 16 ppm or more. With skill and practise, you can make this yourself for pennies per dose. Please see my web site at http://silversol.net63.net/ for more info.
The team discovered that the HSV1 DNA is located very specifically in amyloid plaques: 90% of plaques in Alzheimer's disease sufferers' brains contain HSV1 DNA, and most of the viral DNA is located within amyloid plaques. The team had previously shown that HSV1 infection of nerve-type cells induces deposition of the main component, beta amyloid, of amyloid plaques.
100% might have been a clincher. If anti-virals help, I might have rto eat my worlds.
Most people have HSV1. HSV1 DNA locates in the amyloids. So most people expressing the amyloids would have HSV1 DNA in them.
What's up with the 10% of alzhemier amyloids without the HSV1. It sounds like amyloid metabolism is the problem and HSV1 is along for the ride.
With these findings in mind, it would be interesting if someone were to do a study and see if there's a correlation between Alzheimer's incidence and people who have a tendency to get cold sores. Since only 20-40% (according to TFA) of HSV-1 carriers develop cold sores, I wonder if being susceptible to outbreaks indicates a higher risk of developing Alzheimer's later in life. You'd have to correct for all sorts of environment factors, but still, as someone who gets cold sores something awful that would be a very interesting study. Anyways, great article, it's good news if something comes out of this. HSV in its different varieties is already known to be responsible for quite a few diseases so only good can come out of more research into it.
Might not be the only culprit here. Chicken pox (V. zoster) and Shingles (H. zoster) are related to HSV1 and HSV2. Many people may have had either -or both- of these infections as children or adults and carry the virus in a dormant state in their body. The research does not address these other -possible very prevalent- vectors in AD.
Sig this!
Blanket vaccination policies didn't quite work in the effort to eliminate smallpox.
A change to aggressive targeted vaccintaion policies did the trick.
Nope, I heard that joke several years ago; in fact my wife told it to me, I think she got it from her brother in England.
What's the issue?
I know a lot of people (myself included) that actively avoid kissing, sharing glasses, etc with people that have cold sores.
they think it causes it:
They propose that a weakened immune system allows the virus into the brain.
There, it causes flare-ups in the brain at various times when the person is stressed etc. Basically, just like the cold sores on your lips.... but in the brain.
These cause the cells to create this non-soluble plaque stuff which then gets left behind when the cells themselves die.
The treatment with anti-virals would presumably prevent, or decrease, the number of "flare-ups" in the brain and therefore reduce the rate at which this Alzheimer's inducing plaque is formed.
(although i'm not clear on whether the damage is caused by the plaques or if the plaques are just a marker of all the cells that have been destroyed and the disease is actually caused by that destruction.)
if you've had cold sores and paid attention to how they seem to develop one can see how it would be destructive.
1) You start out perfectly fine.
2) For whatever reason this virus starts reproducing in some of your cells (highly localized)
3) a cluster of blisters forms.
4) After a few days, the "blisters" stop forming and you're left with a moderately significant wound that takes a while to heal.
Now imagine this happening in your brain... and remember that nerve cells, unlike skin cells, don't really reproduce much (if at all).
(Incidentally, i'm one of the people for whom Abreva (an OTC medicine) works very well. If I put it on in time it stops the progression in its tracks. HIGHLY recommended.
now if i could only figure out how to rub it on my brain.....)
Out of "over 16 million doses of Gardasil given" ... "at least 20 women who received the Gardasil vaccine have died, there is no evidence that deaths or serious outcomes were connected to the shot.[28] Where information was available, the cause of death was explained by other factors."
That puts it at a 1 in 800,000 ratio, where most cases were not actually linked to the vaccine.
At one SMALL beach where I live, lifeguards extract over 150 needles per year from the sand, well over 1 every 3 days. I'm willing to bet more than 1 in 800,000 of those needles are `found by accident`, and most of them were used by people with a chronic disease.
Sadly, I had a girl say (almost) those exact words to me recently. I thought she was joking. She wasn't.
I don't see her anymore.
Don't put advice in your sig.