Scientists Hack Cellphone To Detect Diseases

Dave Bullock (eecue) plugs his piece up at Wired on a cellphone modded into a portable blood tester. This could become a significant piece of medical technology. "A new MacGyver-esque cellphone hack could bring cheap, on-the-spot disease detection to even the most remote villages on the planet. Using only an LED, plastic light filter, and some wires, scientists at UCLA have modded a cellphone into a portable blood tester capable of detecting HIV, malaria, and other illnesses. Blood tests today require either refrigerator-sized machines that cost hundreds of thousands of dollars or a trained technician who manually identifies and counts cells under a microscope. These systems are slow, expensive and require dedicated labs to function. And soon they could be a thing of the past."

Comments

Interesting comment on Wired's website

[Adrian Lopez]

Posted by: jamesdionne:

I call bullshit on this one. First off, HIV can be tested for by an ELISA method which is way cheaper than a cell phone camera. And the quality of other lab results are the most important function of those "refigerator" sized analyzers, not because of cost but because you can kill way more people with inaccurate results than with no results at all. I could shine a flashlight at a blood smear and take a good guess at your H&H too, but I wouldn't trust my life to it.

I agree.

Re:But...

[Garrett Fox]

Well, it's not like those countries are literally in the Stone Age. They're dirt-poor by Western standards, but they have access to some modern technology and can scrape together the money for relatively cheap stuff. (Unfortunately this includes Kalashnikovs.) As the West continues to develop cutting-edge technology, the standard for what kind of things the world's poor can afford rises. That is, nobody at all had LEDs until the 20th century.

Inventions like this raise the level of technology available to most of the world, and do more good for more people than (say) yet another model of iPod. One of the main things I've learned from studying history is that the maximum level of technology in a society is less important than the level that the masses have. Making things cheaper is one of the main ways in which technology has advanced; eg. iron is actually inferior to bronze in several ways, but is cheaper.

In fact, in some ways poor countries have had an opportunity to leapfrog the West. If your country has never had a copper-wire phone system, and you're just getting started with phones, you may as well start off with cell phones or fiber optics.

Forget HIV, Malaria is enough to make this cool

[Neuticle]

I can see this possibly evolving into something that would be able to detect malaria infections, malaria is pretty big and easy enough to spot with good magnification and a little bit of training. Parasite laden blood cells are often chock-full of little plasmodium, so they would definitely have different optical properties in this kind of system. This could also probably do a reliable job of some basic blood values like hemoglobin levels, where the item in question has strong, distinct light-absorbing properties, but it won't come close to replacing an actual lab: there are too many things that just don't interact enough or interact distinctly enough with light to be measured that way, even if you had a lab-quality variable-frequency light source.

HIV, however, is a virus, and can not currently be detected or diagnosed microscopically (barring electron microscopes), so I'm a bit skeptical on that point. Besides, we have antibody tests that are cheap, effective and (thanks to foreign aid) available even in the poorest, most remote areas. The problem with testing for HIV is not detecting it, it's getting people tested. There is still a HUGE stigma around it, and people are (often with good reason) worried about the privacy of tests. If this guy has figured out how to detect and, more importantly, identify viruses using light microscopy, he'll be up for a Nobel prize, but I highly doubt that is the case. It's more likely that Wired just embellished the story a bit, which I think is unnecessary since even being able to quickly and reliably detect just parasites in the blood like malaria, leishmaniasis or trypanosomes would be a big help for many in the developing world.

I spent 2 years living in remote, rural Tanzania and some of the clinics near me diagnose malaria in every blood smear they see, because they don't have someone well trained enough to examine the blood, or they don't actually have a functioning microscope (they are freaking expensive, very fragile and hard to get out in the boonies) so they err on the side of caution. Even though they are probably correct a good percentage of the time, people were often "diagnosed" with malaria when they had none of the symptoms: Malaria gets the blame for nearly every ailment. This leads to overuse of anti-malarial drugs, which leads to drug-resistance. I also saw anemia being diagnosed very frequently as well, with out any way to properly test for it. It was the second most popular target for any ailment. "Anemic" people are encouraged to eat a substance made from red clay. It probably has plenty iron so it could actually help and probably can't do any harm, but it tasted about like you would expect dirt to taste.

To make my point: if this all this could do was detect malaria and hemoglobin levels, at even 10x the cost of a cell phone, but as portable and as durable as a cell phone (relative to a microscope that won't survive a car ride), it would make a sizable impact for a lot of people.