Amateurs Are Trying Genetic Engineering At Home
the_kanzure points out this AP story on amateur genetic engineering, excerpting: "The Apple computer was invented in a garage. Same with the Google search engine. Now, tinkerers are working at home with the basic building blocks of life itself. Using homemade lab equipment and the wealth of scientific knowledge available online, these hobbyists are trying to create new life forms through genetic engineering a field long dominated by Ph.D.s toiling in university and corporate laboratories." Reader resistant has a few ideas about how to use this sort of lab: "Personally, I'd like to whip up a reasonably long-lasting and durable paint made with dye based on squid genes that glows brightly enough to allow 'guide lines' to be daubed along hallway baseboards, powered by a very low trickle of electricity. Plus, a harmless glowing yogurt would make for a cool prank."
Someone should do something useful and recreate this.
Just because a few computer companies started out as projects, that does not mean that everything someone starts in their garage is bound to be wildly successfull. I dont get why they must draw the parallels.
At the 24th Chaos Communication Congress there was a lecture about this topic: Programming DNA http://events.ccc.de/congress/2007/Fahrplan/events/2329.en.html (links to torrents on the page).
Yes, I am a molecular biologist by training. This won't work. The reason genetic engineering is carried out in labs is because it requires expert knowledge of protocols, and expensive equipment. In TFA, one of the people interviewed is trying to insert a targeted florescent marker, and struggling. This is fairly trivial to do in the lab, but only with good understanding of basic principles, hundreds of thousands of dollars worth of gear and consumables, and tested/documented protocols. You can't build a space shuttle in your backyard, neither can you successfully build a recombinant bacterium that meets spec in your garage. Just because cells are squishy does not make this equivalent to software development!
Pris: Must get lonely here J. F.
Sebastian: Mmm... Not really. I make friends. They're toys. My friends are toys. I make them. It's a hobby. I'm a genetic designer. Do you know what that is?
Pris: No.
Sebastian: Yoo-hoo, home again.
Toys: Home again, home again, jiggity jig. Good evening J. F.
Just like Bill Joy wrote in Wired ever so long ago. I have thar article printed out here somewhere, and I force it on everyone who will read it. I really think biotech will kill us all, or at least enough of us where the distinction is academic. I'm not worried about nuclear winter, or overcrowding, but the dang microbes. All it takes is one pissed-off bacterium or virus, and we get Stephen King's The Stand. No, I'm not a microbiologist, so I can't tell you, using the correct terminology, why we're all doomed, but I can't help but think that tinkering with life is bad. It might be an accident, but there are also quite a few well-heeled doomsday cults on the planet. Couple that with normal evil and quasi-evil government biowar research, and this freelance crap isn't going to help the situation. We're just too convinced that nothing bad can happen to little old us. The bacteria will win, I tell you.