Slashdot Mirror


New Method To Revolutionize DNA Sequencing

An anonymous reader writes "A new method of DNA sequencing published this week in Science identifies incorporation of single bases by fluorescence. This has been shown to increase read lengths from 20 bases (454 sequencing) to >4000 bases, with a 99.3% accuracy. Single molecule reading can reduce costs and increase the rate at which reads can be performed. 'So far, the team has built a chip housing 3000 ZMWs [waveguides], which the company hopes will hit the market in 2010. By 2013, it aims to squeeze a million ZMWs [waveguides] onto a single chip and observe DNA being assembled in each simultaneously. Company founder Stephen Turner estimates that such a chip would be able to sequence an entire human genome in under half an hour to 99.999 per cent accuracy for under $1000.'"

15 of 239 comments (clear)

  1. Gattica... by Anonymous Coward · · Score: 1, Funny

    Gattica, here we come!

    But at least there's Uma Thurman.

  2. Sub-$1000 genome sequencing by morgan_greywolf · · Score: 4, Funny

    Sub-$1000 genome sequencing will put the creation of 'designer' kids into the realm of the affordable for much of the middle class. Scary stuff. Now we just need to combine that with cheap and reliable cloning techniques and my plans for world domination will be comlete!

    1. Re:Sub-$1000 genome sequencing by Ethanol-fueled · · Score: 3, Funny

      "...my plans for world domination will be comlete!"

      Hopefully you'll fix that nasty intercalary deletion bug first!

    2. Re:Sub-$1000 genome sequencing by morgan_greywolf · · Score: 2, Funny

      I will, but I gotta P first!

    3. Re:Sub-$1000 genome sequencing by CorporateSuit · · Score: 2, Funny

      Hopefully you'll fix that nasty intercalary deletion bug first!

      As long as it's not a missing G, T, C, or A, he'll be OK.

      --
      I am the richest astronaut ever to win the superbowl.
  3. Re:99.3% accurate? by morgan_greywolf · · Score: 5, Funny

    1 Hour Genome Sequencing: 30,000 errors or less or YOUR MONEY BACK!

  4. Re:99.3% accurate? by nbauman · · Score: 1, Funny

    I want a cute little baby velociraptor!

  5. Re:99.3% accurate? by evilNomad · · Score: 2, Funny

    If you got B on the second run you'd be pretty sure it was incorrect.. ;-)

  6. Re:99.3% accurate? by Rayban · · Score: 2, Funny

    Sorry, you're asking for the impossible - I've never seen a well-organized mammoth hunt.

    --
    æeee!
  7. Re:99.3% accurate? by shaitand · · Score: 4, Funny

    If you were sequencing DNA and got a B then you'd seriously need to recheck the equipment (or the competence of the operator). Perhaps a T or a G, or even a C but never a B.

  8. Re:99.3% accurate? by fracai · · Score: 3, Funny

    Oh well. At least it's not the first time somebody missed a point on /.

    Don't you mean "Oh well. At least it's not the first time somebody missed a point on /".

    --
    -- i am jack's amusing sig file
  9. Re:GATTACA is here by oni · · Score: 2, Funny

    Gattaca was supposed to show us a dark future. It was supposed to be a cautionary tale. The message was, "if your DNA isn't good enough, you'll have to make do banging Uma Thermon - poor you."

    I don't think the producers thought their cunning plan all the way through.

  10. Re:99.3% accurate? by jd · · Score: 2, Funny

    That's because Mammoths have no opposable thumbs and therefore no means of becoming organized.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  11. Re:99.999% accuracy by gnick · · Score: 2, Funny

    error's

    That character you're using... I don't think it means what you think it means...

    You must be new here. You see, here on teh interweb, many of us are terribly afraid of word's ending in "s" - Plural's, possessive's, contraction's with the word "is", and occasionally even name's. The apostrophe is a polite way of warning the general reading public that an "s" is approaching so that we can brace ourselve's accordingly.

    --
    He's getting rather old, but he's a good mouse.
  12. Re:99.3% accurate? by TooMuchToDo · · Score: 3, Funny

    Unless of course all three of your compasses are giving you different readings. In that case, you simply yell "Where the hell is my sextant."