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Advance In Making Stem Cells From Skin

KillerBob writes with an advance on the news from a year back that stem cells can be produced from human skin — discussed here. Now Canadian researchers have found a safe way to generate stem cells without using viruses to modify the genome, a process that can have its own dangers. "The ethical debate over embryonic stem cell use may soon be moot, thanks to a Canadian team of researchers who, together with a team out of Scotland, has found a safe way to grow stem cells from a patient's own skin. The revolutionary finding, described in a paper published yesterday by the international science journal Nature, means doctors may be one step closer to treating a multitude of diseases, including Alzheimer's, diabetes and Parkinson's."

8 of 139 comments (clear)

  1. Every Skincell is Sacred by neoform · · Score: 5, Funny

    We must move to ban all exfoliating soaps! Murder!!

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    MABASPLOOM!
  2. Lame lame lame by grub · · Score: 5, Funny

    Make stem cells the way nature intended: from aborted fetuses.

    Quit wimping around.

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    Trolling is a art,
  3. Re:Just around the corner... by DMUTPeregrine · · Score: 5, Informative

    Embryonic stem cells are not that useful for treatment, even though they are very useful for research. The advantage of stem cells is that they let you grow tissue that won't be rejected, since it's identical to that of the host. Embryonic stem cells aren't the same, and thus get rejected. Thus, adult stem cells are what we want for actual treatments. Embryonic cells are just easy to do research on, IE "finding ways to use stem cells to tread medical conditions." Once you know how to do it with the embryonic cells you can use the adult cells to actually implement the treatment.

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    Not a sentence!
  4. Re:Not quite... by heatseeker_around · · Score: 5, Insightful

    as my wife (who does research and writes articles in neuroscience) says: 90% of the research is to find something enough interesting to get more money for your researches. It's not bad, it simply is how it works in science research. When you write an article, you always have to project your discovery into the future and tell how it will (not would) affect and save the life of many sick people, even if you know it will happen in 100 years at last.

  5. Re:article by drosboro · · Score: 5, Informative

    Oh, and there's a news story linked from Nature's front page on the topic:

    http://www.nature.com/news/2009/090227/full/458019a.html

    It also links to a second paper at:

    http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature07864.html

  6. Re:Wrong way around... by PitaBred · · Score: 5, Informative

    You have to have the stem cells before you can move to using them for something. As they are, they're really expensive, rare, and possibly dangerous to make so they have to be screened very well. This new process makes experimentation and trials more likely. Gotta lay the foundation before you build the building.

  7. Re:Just around the corner... by rahvin112 · · Score: 5, Informative

    Embryonic stem cells can have the nucleus removed and replaced with the hosts DNA thus creating an embryonic stem cell with the DNA markers of the patient. The delay in advancing Stem cell's is at least a decade now as without use of embryonic stem cells they haven't developed the techniques to properly use them even if they do find a way to make adult version stem cells without using embryonic material.

    The great fear of the abortion movement is that the public would become aware that the vast majority of embryonic material wouldn't be from abortion (where 95% of the material is mutilated tissue of little value) but the unused fertilized eggs contained in hundreds of thousands of fertility clinics around the country that are no longer needed by the parents that successfully produced children. Most importantly that these parents would then donate these unused fertilized eggs to curing diseases like Alzheimer and cancer, regrowing damaged organs or new skin for burn patients. It's ironic that the anti-abortion movement would rather see the eggs destroyed than used.

  8. Re:Just around the corner... by !coward · · Score: 5, Insightful

    Um.. You DO realize that what you refer to as "Big Pharma" are multinational business corps with many research facilities spread throughout the globe, who make extensive use of grant programs to get Universities worldwide to do some of their legwork, and who basically have their hands in pretty much all the "pies". There aren't US "Big Pharma" corps, anymore than there are European "Big Pharma".. They boil down to just a handful of entities who directly own or control hundreds (if not more) of subsidiaries, and they're ALL global players.

    Yes, the fact that the previous US President banned research on (embryonic) stem cells did put a wrinkle on the worldwide research being done in the field.. On the one hand, the US market for drugs and medical treatments is too big to ignore, so there was less of an incentive to develop technologies, procedures and know-how on stuff that the big corps might not be able to deploy in such a profitable market (and thus reducing their perceived return on that investment). On the other hand, there are many great minds working in those fields in the US (both native and foreigners), often with ties to education institutions, and it wouldn't be so easy to uproot all those people just so they could send them somewhere where they could legally do/continue research.

    So, for the "Big Pharma" it just made sense to look into other venues of research, or for ways to bypass the ban by using other types of cells with which you could eventually get the same results. And in this regard, while I consider the ban to have been a huge mistake (especially the totally bogus reason for said ban), we haven't really lost anything because the other venues pursued would have to be done eventually anyway, all the better that it happened when the corps were so eager to get results that could translate into money.

    I don't know if there were (many) other countries following suit on the ban, but I do know that it was and still is a sensitive issue in many countries in Europe, so maybe in the end the money ended up drying in other places too.. But it hasn't been completely abandoned either, as I remember reading several studies published these last 8 years relating to research done on embryonic stem cells.

    Directly and indirectly, the US does have a BIG impact in the world in many areas (which is probably why so many of us follow what happens over there so closely -- and become so obnoxiously opinionated).. But don't think others wouldn't step forward to pick up the slack if you guys over there went the Amish way, either. :)