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Scientists Reverse Muscular Dystrophy In Dogs

Al writes "Scientists have taken a step toward developing a cure for Duchenne muscular dystrophy (DMD) by successfully treating the condition in dogs using a novel genetic technique. The scientists used a method called exon skipping, which involves adding a genetic 'patch' to block transcription of a portion of the gene involved in DMD. This puts the remaining genetic sequence back in order, essentially creating a much less severe version of the condition. The scientists recorded some remarkable video footage showing the resulting improvements in several dogs with naturally-occurring DMD. More work is needed before the treatment can be given to humans, however, because DMD sufferers often have different genetic mutations."

4 of 143 comments (clear)

  1. Re:Beware by Anonymous Coward · · Score: 5, Funny

    "IE"? What is that? I cannot recall... :P

    It's more commonly known as "the Firefox downloading tool".

  2. Great News by Nos. · · Score: 5, Informative

    I just found out that two nephews of three are positive for DMD. This basically confirms that my sister-in-law is a carrier. We're in the middle of trying to determine if my wife is a carrier, and thus if our two sons are at risk. To say the least this is a very stressful time in our lives, and there are no quick answers. However, seeing a big jump like this in treatment is great news.

  3. Slashdot makes my day by Naked+Jaybird · · Score: 5, Insightful

    As one diagnosed with Becker's MD, a milder form of DMD, I, for one, welcome my new exon-skipping overlords. For those of you who are wondering if you should go to the gym, run, jog, shoot hoops, or play soccer today. I give you the same advice that I give to my three boys: Run, because you can.

  4. Re:Tag: whatcouldpossiblygowrong by vishbar · · Score: 5, Funny

    The absolute worst thing that could go wrong is that the people being treated die from the treatment

    Nuh-uh. Did you ever see 28 Days Later?

    Zombies. The worst thing that could go wrong are zombies.

    --
    Ride the skies