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Scientists Begin Mapping the Brain

Raindance writes "A team at the University of Utah has unveiled a system to map and digitize brain tissue — thus fulfilling one of the long-standing holy grails of neuroscience and enabling for the first time in-depth analysis of how mammalian neural networks function. So far, maps for the entire retina and related neural networks have been released; no ETA on a full-brain digital reconstruction yet. (One of the lead authors hangs out here on Slashdot.)"

8 of 129 comments (clear)

  1. Re:Now... by Yvan256 · · Score: 4, Insightful

    You already have one.

  2. Re:The inevitable result... by thepotoo · · Score: 4, Interesting

    Bullshit. A complete map of a brain of someone with and someone without gene XYZ will tell us about the role played by gene XYZ without the ethical or temporal problems associated with creating an XYZ knockout. A neural network running a simulation of a human brain would be a Turing-complete strong AI. Throw a evolutionary algorithm onto this, and you can start looking at where different types of selective breeding could take humans, or the long-term effects drugs could have on personality.

    That's off the top of my head; there'll be a million and one uses for this eventually (ever wanted to live forever inside a computer?). Besides, this is in the preliminary stages, they are still doing stuff like classifying synapses by hand. By the time this is workable, we may already know what consciousness is.

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  3. Re:The inevitable result... by brian0918 · · Score: 3, Interesting

    There's certain schools of thought that subscribe to the view that if you can save a complete state of the brain, there's no reason why, with exponentially increasing compute, you couldn't come along later and start it running again

    That would be determinism, and would require precise measurements for future reproducibility - the further into the future you go, the more precise they would have to be to remain accurate to reality. And it in no way accounts for stimuli, the very things of which one is conscious. So maybe you could restart a simulation, and it could last a short time, but it would not remain accurate long, and would not be able to handle changes in input.

  4. Re:The inevitable result... by interkin3tic · · Score: 4, Interesting

    This may be of use for diseases, but the greatest use - understanding consciousness - is still well beyond simply mapping the brain

    A variation on the sentiment "Why bother investigating this, it's beyond our understanding and is useless," which has been posed at some point to every serious scientific inquiry. "Why study fungus, you can't do anything useful with it!" is probably something Flemming heard right before he discovered penicillin.

    Fortunately it's often wrong. In this case, it seems to me that knowing the map of a brain could have some real tangible uses

    -Understanding the sequence of wiring a brain, we know some things about the order in which brain cells develop, and we know unconnected neurons die, but beyond that I'm not sure we know anything. Is there an organization to how the brain initializes itself? Could this be one thing that goes wrong in, say, autism?

    -Better understanding of the interconnectivity of different regions of the brain. Obvious uses there for dealing with lesions to the brain, if you learn from this study that one of the areas damaged is highly connected to a distant part of the brain, you might want to watch out for effects on that other part of the brain

    -Helping us understand how or if new neurons generated in adulthood integrate into the already existing, quite complicated network

    -altering something and seeing how that affects the brain map, to study the plasticity of the brain and possibly learn how to learn better

    That's just the ones I could think up, there are undoubtedly more reasons one of the authors could fill you in on, and there are probably even more uses that even they haven't thought of, that some other researcher will.

    Anyway, since when did science ever need to have a clear use in mind before we did something? If you're anything like the typical slashdotter, you don't bother asking "What good will that do" when discussions of "Let's land on the moon or mars" come up. I would argue that this is clearly more useful than that, but that doesn't matter, it's not about knowing all that we can gain from an endeavor in advance.

  5. Re:The inevitable result... by MozeeToby · · Score: 5, Insightful

    A neural network running a simulation of a human brain would be a Turing-complete strong AI

    I understand what you're saying here but there are a lot of non-trivial hurdles to get over, even assuming you can accurately scan and simulate the brain.

    First, the brain also includes a lot of chemical transmitters which we really don't understand the function of yet. You would have to include them in your model as well, including the ones that don't originate in the brain.

    Second, you have to interpret the simulated neuron firing into something that you can actually understand. It's pretty pointless for your brain-on-a-hard-drive to be saying 'hello' if you can't understand what it's saying. An accurate simulation of my mind would have all the neurons that control my breathing, lips, tongue, and vocal cords firing like crazy, but good luck figuring out what I'm saying.

    Third, you have to be able to supply meaningful input into the brain. You're essentially talking about submitting a consciousness (assuming your simulation is 100% accurate) to the most horrible sensory deprivation imaginable. In order for your research to be useful, you would have to supply it realistic input (including feedback based on it's output) otherwise the brain would change drastically just from that.

  6. Re:This is a great achievement... by MrEricSir · · Score: 3, Funny

    Are you serious? There are plenty of samples of digitized vaginal tissue on the internet already. Many require credit cards, however.

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  7. One word. by Sybert42 · · Score: 3, Insightful

    Singularity

  8. I'll give it a go... by rts008 · · Score: 3, Insightful

    It seems everyone is too busy being flippant or dismissive towards you, so I will attempt to give you an answer.

    1. Neuroscience is considered important in the medical field. The nervous system is important for almost every other bodily function if for no other reason than it is the control and communication system of the body.

    2. the brain is one of the least understood of our organs, and arguably, one of the more important ones. Anything we can learn about it helps a lot at this early stage.

    3. Scientists/med researchers are people too, and since people have diverse interests and passions, so do the scientists. They gravitate to fields that hold an interest/importance to them. Freedom of choice, etc....there is no pool of researchers and scientists that are assigned fields of study by some group/organization.

    4. Because it's there. This is a central drive inherent in humans...to 'boldly go where no man has gone before', and can be attributed to many reasons to do so.
    Curiosity, exploration for the thrill or ego(I was first!!!!), need to contribute/help, revenge/righting a perceived wrong...

    Yeah, this is all just basic stuff, but can be easily overlooked or taken for granted. On one side(funding) you have special interests, on the other you have researchers with special interests. They have a habit of finding each other.

    It gets to be easy to sit back and wonder 'why this and not that' from the outside. Maybe this will help:
    (I'm not asking for an answer, just giving food for thought, but it's okay to answer!)

    What do you do for a living? What got you into that, and why is it important to you? If not important to you(other than to make a living), then what would you want/like to do? Apply those answers to your question, and you may have an answer.(not trying to be an ass, but it's not an 'easy/one answer' question.

    On a more personal note, I'm all for neuroscience to blast forward. At my age, my mind is in the best shape of any of my other 'parts', and I would love to be able to go into a body shop and have my brain transferred(by some means) to a new body. :-)

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