Slashdot Mirror
Merck Created Phony Peer-Review Medical Journal
Hugh Pickens writes "Don't believe everything you read on the internet is a good rule to follow, but it turns out that you can't even believe a 'peer reviewed scientific journal' as details emerge that drug manufacturer Merck created a phony, but real sounding, peer-review journal titled the 'Australasian Journal of Bone and Joint Medicine' to publish data favorable to its products. 'What's sad is that I'm sure many a primary care physician was given literature from Merck that said, "As published in Australasian Journal of Bone and Joint Medicine, Fosamax outperforms all other medications...."' writes Summer Johnson in a post on the website of the American Journal of Bioethics. One Australian rheumatologist named Peter Brooks who served as an 'honorary advisory board' to the journal didn't receive a single paper for peer-review in his entire time on the board, but it didn't bother him because he apparently knew the journal did not receive original submissions of research. All this is probably not too surprising in light of Merck's difficulties with Vioxx, the once $2.5 billion a year drug that was pulled from the market in September 2004, after a study showed it doubled the risk of heart attack and stroke in long-term users resulting in payments by Merck of $4.85 billion to settle personal injury claims from former users, but it bears repeating that 'if physicians would not lend their names or pens to these efforts, and publishers would not offer their presses, these publications could not exist.'"
Oh no. They will get a fine far less than the money they made doing it, which is corp-speak for "please keep doing it." None of the executives will get any time. None of the doctors involved will get a reprimand, heck, this is just an advertisement that they play ball. On to the next corporate gig.
- None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
Has any company ever gotten away with stuff like this in recent times? Doesn't the availability of everything on the Internet ensure that someone somewhere, doing just a little research, will call 'bullshit' when a certain journal/reviewer goes overboard in praising just one company?
I've seen a lot of seedy stuff in my time, but this might just take the cake with respect to all-time industry lows. To hell with the music industry; this is beyond reprehensible. They're playing with peoples' lives. Somebody please tell me someone's going to jail for this.
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Why is it the publishers job to censor or police what people publish?
I can understand why it would be a professional consideration for physicians to not assist something like this, but going after the publisher morally is crazy. Let's not start witch hunting now.
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the article forgot ...and publishers would not offer their presses, AND MANUFACTURERS DID NOT OFFER THEIR MONEY TO SAID PHYSICIANS AND PUBLISHERS these publications could not exist
Sleep your way to a whiter smile...date a dentist!
So the study was cherry-picked: deceptive, because what is good in the short term can be bad in the long term.
This is why drugs oughtn't be marketed to patients. If an ad says a drug has fared well in a study, Joe Regular will assume it's automatically a good thing. He doesn't know a good study from a bad one, or whether a medical journal is reputable - or even exists. A physician has a far greater probability of distinguishing bullshit from actual facts than a layperson, though it doesn't of course always hold true.
Who's to say only the "American people" got fucked over? It's usually the rest of us.
When some greedy corporation in the US gets the urge to over-reach common sense in the name of profit, people die. Hello Halliburton, Blackwater - sorry, "Xe" - Merck, Chevron, Shell, Union Carbide, Monsanto - This is going on all around you, every day. It's just the kind of business y'all have been trained to tolerate, encourage and sponsor. And let's be frank, the absurd US military budget is largely what it is so that they can keep doing it with impunity. Nice little system.
If a corporation is legally a person, then let them be shut down and incarcerated like the murderers and thieves they are.
you had me at #!
Just who the fuck can we trust these days? What makes these executives think they can act with impunity? Oh, right, they probably can. Yay, free market!
---Technology will liberate us if it doesn't enslave us first.
Why is it the publishers job to censor or police what people publish?
Elsevier is a major scientific publisher; articles appearing in their journals are generally considered respectable. The fact that they were willing to publish a "journal" like this one will do a lot of damage to that reputation. Researchers will be less likely to submit high-quality articles to other Elsevier journals, and university libraries will look more closely at the subscription package deals which is where the journal publishers make most of their money.
That's why.
The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
Suppose I am a publisher. Suppose I take a job from the mafia...
If I were a publisher by the name of Elsevier, I would be very, very careful what journals I accept to publish. Elsevier is a very high profile outfit, publishing most of the reputable journals in my discipline (biotech) and many others. Backing up a shonky outfit like this was ill-considered, and whoever's idea it was deserves to be fired.
Of course, we ARE talking about prescription drugs here. If we accept that a substance is so dangerous (at least potentially, when used the wrong way, in the wrong situation etc.) that Joe should not be able to buy it at all on his own, then the notion that it shouldn't be advertised to him either makes sense. Or, put another way - if a drug can be advertised to him, then how do you justify not allowing him to buy it?
There's also the issue of truth (and lies) in advertising. Cherry-picking studies to create an impression that medication FOO will help with condition BAR when in reality, it will actually and demonstrably make it worse, should be illegal as well. In fact, I'm pretty sure it is - the relevant laws just aren't enforced the way they should be.
Even Elsevier is subject to Sturgeon's second law.
That would be like suing HP for selling the Laserjets that were used to print it.
That clearly is going too far, but going after the hosting provider does happen.
You have a right to political free speech, but you do not have a right to commercial free speech. You also don't have a right to tell lies.
Keep in mind that pharmaceutical companies don't have full freedom in the design of trials. It is, fortunately, a very highly regulated activity.
This trial was probably reviewed by boards of experts and blessed by the regulatory organizations, who approved both the length of the study and the criteria for enrolment. A six-week study may very well produce misleading results, I couldn't comment on that, but it would not be the first time people defined stupid plans with the best of intentions. Typically trials are kept at a minimal length at first to reduce the risk to the volunteers, and then gradually extended in later phases of development.
That would be like suing HP for selling the Laserjets that were used to print it.
Nope - the publisher actually gets to see the content before publishing it. What if they put out a magazine full of kiddie porn? Could they claim "we only publish it?" Didn't think so.
You're confusing the publisher with the printer. The publisher is responsible for hiring the editors (you know, the people who are supposed to be reviewing what's published - unless it's slashdot), etc., and will contract with a printing company for the actual print run.
Why is it the publishers job to censor or police what people publish?
A publisher, at least one in the dead tree business, always served as a gatekeeper. Admitting contributions that enhanced the publication's overall presentation to the consuming readership could be printed, while flamebait and trolls were consigned to the trash bucket.
Unfortunately, that practice does not seem to have carried over to the internet.
== First cross river, then insult alligator.
Most if not all socialized medicine care DO NOT use civil servant for health care. They use real doctor and nurse that they pay off fater the care has been done. Such doctor have as much incencitive to do their job good as they do in a private health care concept as the US, but with the added benefit that the centralized healthcare allow for bigger cost reduction on the masses. Whereas private health care, unless in the hand in a very few, will only be a set of balkanized private area.
C. Sagan : A demon haunted world:
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visit randi.org
Just as there is the Proprietary vs OS struggle in Software Engg., there is now a parallel in the field of scientific publishing.
Open Access Journals [http://www.doaj.org/] are all about free scientific information instead of billions charged by these greedy ba$tard$.
An article costs approx 10$ at publishers like elsevier/merck, which can, like, feed a whole family in my country for a full week!
And the most outrageous part is that sometimes that article would be the result from research funded by my taxmoney and my government while elsevier just earns off it for (virtually) nothing!
Die M$, Die Elsevier, Die Die
Jai Ho Open Source!
Okay, that's just plain treasonous.
If a company authorized by The People to do business for our benefit goes out and instead defrauds The People, then We have every right and reason to revoke their charter and relegate them to oblivion. And we should!
Yeah, it would mean the loss of some jobs and revenue for the various entities in their web, but it will do more good in the long run. First, the talented people working for this shoddy operation would be freed up to pursue their own eithical enterprises, and second, it would set the proper example and scare the shit out of other companies that might be contemplating or engaged in similar kinds of folly.
Honestly, this is an issue where a company didn't care that it might kill us all so long as they profited, and as far as I'm concerned that's no less than treason.
End them. End them now.
-- thinkyhead software and media
Bees.
Anaphylatic shock.
Why? Especially in Australia, known for some of the most deadly animals in the world!
There are so many bees.
Now, how many asprin are sold?
>>>Corporations are people like you and I with a right to free speech.
The *People* have a right to free speech. The corporation does not. It has no more right to free speech than a rock. If the Merck CEO wants to publish things in his own name (with jail-time if it turns-out his lies led to deaths), that's fine but Merck the soulless entity does not have rights. Only individuals have rights.
"I disapprove of what you say, but I will defend to the death your right to say it." - historian Evelyn Beatrice Hall
We've known about the perils of phosphorous exposure, leading to phossy jaw, or basically the rotting-out of the jawbone, since well before the strikes of the late 1800's in England's match factories. More historical data here.
The idea that Merck is in any way 'surprised' by this turn of events, when their drug is essentially the same substance at work in the body more than a century ago, is well beyond the outer limits of credibility. Never mind the sharp increase in cases of osteonecrosis of the jaw just in the last few years, since the introduction of bisphosphonate drugs -- by Merck.
Corporations generally incentivize behaviours that are sociopathic on an interpersonal scale but deemed favorable by investors -- in a nutshell, maximize profits by any means available. This ethical vacuum is one of the real flaws of capitalism in its current implementation. Merck's actions are therefore not in the least surprising, and stand as a pointed reminder that corporate excesses must be held in check by some other external mechanism that is not subject to conflicts of interest. This is generally identified as government regulation, though we have seen time and again how government interests can be made to align with those of the corporations and in opposition to those of the public that the government is ostensibly supposed to serve and protect.
Food for thought. Ain't nothing new under the sun, as it's all recurring patterns of human behaviour. The devil is in the details.
Cheers,
"What in the name of Fats Waller is that?"
"A four-foot prune."