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Scientists Create RNA From Primordial Soup

Kristina at Science News writes "The RNA world hypothesis proposed 40 years ago suggested that life on Earth started not with DNA but with RNA. Now a team of scientists bolsters this hypothesis, having assembled RNA in the lab from a mixture that resembles what was likely the primordial soup. 'Until now,' Science News reports, 'scientists couldn't figure out the chemical reactions that created the earliest RNA molecules.' The new work started the RNA assembly chemistry from a different angle than what earlier work had tried."

19 of 369 comments (clear)

  1. Re:Abiogenesis.... by jawtheshark · · Score: 5, Informative

    I was on my netbook... I'm usually logged into my Troll account on that one. Should have checked. Oh, well, got plenty of Karma...

    --
    Ahhh...the great dumpster continuum. Many a free computer will be found there. -- sowth (748135)
  2. Re:One word.... by Jugalator · · Score: 5, Insightful

    That they accidentally got RNA and thought they created it themselves? Did you read the article?

    âoeBut while this is a step forward, itâ(TM)s not the whole picture,â Ferris points out. âoeItâ(TM)s not as simple as putting compounds in a beaker and mixing it up. Itâ(TM)s a series of steps. You still have to stop and purify and then do the next step, and that probably didnâ(TM)t happen in the ancient world.â

    Sutherland and his team can so far make RNA molecules with two different bases, and there are still another two bases to figure out.

    --
    Beware: In C++, your friends can see your privates!
  3. not that big of a deal by anticlone · · Score: 5, Informative

    they found a reaction pathway - that does not prove it happened that way - I too thought the article title indicated spontaneous generation of RNA from primordial soup.

  4. Ignoratio Elenchi by Anonymous Coward · · Score: 5, Informative

    Demonstrating that another link in the evolutionary chain can happen without conscious intervention (spontaneously and mechanically) does not demonstrate the non-existence of an intelligent designer.

    It, at best, removes a point that was previously used to defend ID.

    But, logically, the inability to prove something does not constitute a disproof (that would be the fallacy of Argumentum ad Ignorantium).

    Disclaimer: I am not an ID proponent. I am just a logician.

    1. Re:Ignoratio Elenchi by retchdog · · Score: 5, Insightful

      Demonstrating (something) does not demonstrate the non-existence of an intelligent designer.

      Indeed; nothing can.

      --
      "They were pure niggers." – Noam Chomsky
    2. Re:Ignoratio Elenchi by digitalunity · · Score: 5, Funny

      God crushing you nonbelievers with rain of sulfur and fire would settle the matter nicely.

      I'm not holding my breath though.

      --
      You can't legislate goodness. Let each to his own destiny, by will of his freely made choices.
    3. Re:Ignoratio Elenchi by spun · · Score: 5, Insightful

      No, it wouldn't settle anything. Any being sufficiently more powerful than you can convince you that it is omnipotent. Any being sufficiently more clever than you could convince you that it is omniscient. An advanced alien race, claiming to be God, could determine who believes in God and who doesn't, and rain sulfur and fire on the nonbelievers, so a rain of fire and sulfur from something claiming to be God would not prove God exists, sorry.

      --
      - None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
    4. Re:Ignoratio Elenchi by Polumna · · Score: 5, Funny

      Come on, man, this is slashdot. You could have made your whole point with just the words: "Star Trek V" ;D

    5. Re:Ignoratio Elenchi by MojoRilla · · Score: 5, Insightful

      Neither the laws of physics nor the complexity of life in any way provide objective evidence that there is an omnipotent, supernatural god. They can also be evidence that complexity can arise from simplicity, and that the universe happens to have hospitable conditions for life.

      Only someone who believes in god would see those as evidence of god. Don't feel bad though. Your ape hierarchical mind is probably hardwired to believe in god. Believing in hierarchy is good for the group.

    6. Re:Ignoratio Elenchi by Darby · · Score: 5, Insightful

      d)it's a test of faith.

      No, that's not d), that's just c)he likes to play mind games, so why bother worshiping him?

      "tests of faith" are idiotic mind games. What sort of a worthwhile supreme beings gives us good brains with the ability to reason and only rewards the people who are complete failures?

      Obviously a only sleazebag beneath our contempt.

      The OP covered all possible possibilities.

  5. Misleading Article Title by ThistleForce · · Score: 5, Insightful

    Anyone that only scans the synopsis is going to get the wrong idea. Read the article...it's more than likely that this never occurred in nature. Since when do organisms add material and cleanse and add and cleanse? Who threw the sugar in the first primordial soup? Where would RNA get it's instructions? There are too many holes... this isn't a breakthrough in science, It's an episode of "The Frugal Gourmet"

  6. A flowchart might be helpful by reverseengineer · · Score: 5, Informative

    This is the reaction sequence that's being proposed here: link.

    Previously, the sticking point was that there was no logical way for the sugar (ribose) to spontaneously attach to the base. Organisms use enzymes to transfer a ribose phosphate group to a base, but of course, in the time before enzymes could be coded for, that wouldn't be possible. This sequence neatly sidesteps that, and also provides a more logical reason for phosphate to be involved; it is the reagent that attacks that tricyclic pyrimidosugar, breaking the bond to form ribocytidine phosphate.

    Coincidentally, UV light deaminates cytosine to form uracil, which is where that second base comes from. This is why DNA uses thymine instead of uracil, by the way- as the archival storage medium for our genetic information, it would be unwise to have one base easily interconvert into another. The shorter expected lifetime of RNA means the interconversion is not a concern, though.

    --
    "FDA staff reviewers expressed concern about the number of patients who were left out of the study because they died."
  7. Re:Abiogenesis.... by jawtheshark · · Score: 5, Insightful

    They're just trying to correct injust mods... While I'm there and I'll risk some Karma....The origin of life by cdk007. Abiogenesis illustrated.

    --
    Ahhh...the great dumpster continuum. Many a free computer will be found there. -- sowth (748135)
  8. Godless Science loses *another* battle! by Dystopian+Rebel · · Score: 5, Funny

    "Sutherland says [...] 'The key turned out to be the order that the ingredients are added and the way you put them together -- like making a soufflé.'"

    How much clearer does it need to be made to you amoral materialists that cooking dinner needs *a Chef*?

    The only thing I regret is that Sutherland compared God's Work to making a "soufflé". Couldn't he have used a good Christian American recipe?

    Like omelette!

    --
    Rich And Stupid is not so bad as Working For Rich And Stupid.
  9. You forgot... by tool462 · · Score: 5, Funny

    d) God is actually a woman. Powerful, but insecure, and she needs you to show her how much you love her all the time. If you don't, she'll get depressed and eat her weight in mint-chocolate chip ice cream, in which case she'll end up omnipresent in more ways than one.

  10. Re:rna vs dna by JoshuaZ · · Score: 5, Informative

    DNA (Deoxyribonucleic acid) is generally double stranded (classic double helix) and is more robust than RNA (ribonucleic acid) which is generally single stranded. Both use a base 4 code of triplets of certain additions to contain information (normally denoted C,G,A and T). However, RNA has a slightly different set of bases (having uracil in the place of thymine so U instead of T). Almost all life on earth uses DNA to store information in its long-term form and makes RNA when it needs to make proteins. This is a process known as transcription http://en.wikipedia.org/wiki/Transcription_(genetics).

    The primary reason why this discovery is a big deal is that there is a hypothesis that all life started out as using RNA and only later evolved to use DNA. This is known as the RNA world hypothesis- http://en.wikipedia.org/wiki/RNA_world_hypothesis This is a very popular idea in abiogenesis research. There are number of avenues of evidence for thinking this: Essentially, the major problem with a DNA first model of abiogenesis is that DNA cannot normally reproduce itself without proteins. Moreover, DNA cannot produce proteins without the aid of RNA. However, properly chosen RNA strands can reproduce themselves without protein assistance. Moreover, RNA can directly mediate the synthesis of proteins. So if one can find a procedure that can plausibly produced RNA then one can handle most of the problems of abiogenesis in one fell swoop.

  11. You may be looking for this quote. by copponex · · Score: 5, Interesting

    Is God willing to prevent evil, but not able? Then He is not omnipotent. Is He able, but not willing? Then He is malevolent. Is He both able and willing? Then whence cometh evil? Is He neither able nor willing? Then why call Him God?

    -Epicurus, 300 BCE

    The refrain from fundamentalists, Christian and Muslim and Jew alike, is because he is God, and he said so, according to this really old book. Which is usually the inerrant word of God - they just can't agree on which version is the "perfect" word. Once you try to engage someone who firmly believes that they know what God thinks, there's no use in trying to apply logic.

    One of my favorite David Cross bits is where he's asking out loud for the name of the television show where there's this guy on stage, and everyone in the television audience believes he can talk to the dead. The crowd in front of David keeps shouting out "Crossing Over!"

    And then David says, "Oh no, it was church, it was church."

  12. Trifecta! by spun · · Score: 5, Insightful

    You just made three unsupported and ridiculous assertions as if they were a logical argument. Nice hat trick.

    Religion does not need to rely on faith. Buddhism certainly doesn't, but I know some consider that a philosophy, not a religion. Still, it is listed as a major world religion, and it requires no one to take anything on faith.

    Predestination and free will are both pointless human speculations unsupported by any human experiences, and if free will were real, it would be a curse, not a gift, especially considering your God's planned punishments for going against arbitrary rules that you have no way of knowing came from Him.

    If God were to be in residence and free will were real, God's presence would not diminish free will. So what? At most, nobody would choose to sin anymore. I don't choose to froom, either, and my not being able to choose to froom does not diminish any free will I may have.

    But people could still choose to sin knowing God existed, I know I would, just to register my disapproval of God's arbitrary and unjust actions. Infinite punishment for finite transgressions, my ass. Fuck you, God, I'm going out to fuck a guy JUST TO PISS YOU OFF, YOU SHIT! I'm not even gay, I'll probably hate it, but I'm going to do it just because you said you'd torture me forever if I did. I don't negotiate with terrorists.

    --
    - None can love freedom heartily, but good men; the rest love not freedom, but license. -- John Milton
  13. Evidence of what? by interactive_civilian · · Score: 5, Insightful

    Life is complex and it works well. It's not proof, it's evidence. The laws of physics yield a consistent universe. It's not proof, it's evidence.

    Both of these things are only evidence of themselves. Nothing more. You cannot logically extrapolate these things into anything more than they are without direct evidence of something more. No matter how much evidence the universe gives of its own existence, it does not point to anything beyond that, be it God or invisible unicorns or Flying Spaghetti Monsters, sauce be upon him, or anything else. The current body of evidence points only to its own existence.

    If you want to posit the existence of God, based on the evidence provided by the universe, then you need direct evidence of God (well, you also need a clear, falsifiable definition of God). Otherwise, Occam's Razor gives us the more likely conclusion. Given the same body of evidence, the simpler explanation tends to be the correct explanation, unless more evidence appears to show otherwise.

    In this case, the body of evidence: The universe.

    - H0.) The universe just exists.

    - H1.) The universe exists because God created it. God just exists.

    Given the same body of evidence, H0 is the more likely explanation, and there is no REASON to assume H1 without further evidence.

    While you cannot prove a negative, in science, lack of evidence for H1 is provisional evidence for H0. Also, any scientist knows that you can NEVER prove anything based on observation. You can only disprove it OR decrease the likelihood of its falseness.

    NB: Most of the "you" in this post is the general "you" not a specific "you" to the parent post.

    --
    "Empathise with stupidity, and you're halfway to thinking like an idiot." - Iain M. Banks