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Human Language Gene Changes How Mice Squeak

archatheist writes "Researchers at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany have engineered a mouse whose FOXP2 gene has been swapped out for a different (human) version. This is interesting because the gene is implicated in human language, and this has changed how mice squeak. 'In a region of the brain called the basal ganglia, known in people to be involved in language, the humanized mice grew nerve cells that had a more complex structure. Baby mice utter ultrasonic whistles when removed from their mothers. The humanized baby mice, when isolated, made whistles that had a slightly lower pitch, among other differences, Dr. Enard says. Dr. Enard argues that putting significant human genes into mice is the only feasible way of exploring the essential differences between people and chimps, our closest living relatives.' The academic paper was published in Cell."

8 of 185 comments (clear)

  1. this can only end.. by timmarhy · · Score: 5, Funny

    ... with ultrasonic zombie mice.

    --
    If you mod me down, I will become more powerful than you can imagine....
    1. Re:this can only end.. by x2A · · Score: 5, Funny

      This is just the beginning. They started off with a cut down version of the gene (due to patent restrictions on the method used in working with the full gene) that only allows the mice to squeek in the lower tone, do the high pitch whistle, and make one other noise, such as checking its email. The three squeek limit will be a limitation until the Mice Generation 7, when they'll be able to have as many squeeks as they like, but the amount of memory they can use will be limited. This is of course until the EU gets their hands into them, and they will be born without an ability to browse.

      --
      The revolution will not be televised... but it will have a page on Wikipedia
    2. Re:this can only end.. by Jurily · · Score: 5, Funny

      Is that such a bad thing?

      One Celine Dion was enough, thank you.

  2. Life imitates art? by DamienNightbane · · Score: 5, Funny

    This is how The Secret of Nimh began, isn't it?

  3. First spoken humain words... by Anonymous Coward · · Score: 5, Funny

    Pinky, are you pondering what I'm pondering ?

    1. Re:First spoken humain words... by Anonymous Coward · · Score: 5, Funny

      I think so Brain - but how are we going to get Natalie Portman and Jenna Haze into a room together with a bucket of grits?

  4. Re:Interesting, yet I don't want the results... by unfasten · · Score: 5, Funny

    Emotions or not, I'm still eating cows.

    A large dairy animal approached Zaphod Beeblebrox's table,
    a large fat meaty quadruped of the bovine type with
    large watery eyes, small horns and what might almost have been an ingratiating smile on its lips.

    'Good evening', it lowed and sat back heavily on its haunches, 'I am the main Dish of the Day. May I interest you in the parts of my body?'

    It harrumphed and gurgled a bit, wriggled its hind quarters in to a more comfortable position and gazed peacefully at them.

    Its gaze was met by looks of startled bewilderment from Arthur and Trillian, a resigned shrug from Ford Prefect and naked hunger from Zaphod Beeblebrox.

    'Something off the shoulder perhaps?' suggested the animal, 'Braised in a white wine sauce?'

    'Er, your shoulder?' said Arthur in a horrified whisper.

    'But naturally my shoulder, sir,' mooed the animal contentedly, 'nobody else's is mine to offer.'

    Zaphod leapt to his feet and started prodding and feeling the animal's shoulder appreciatively.

    'Or the rump is very good,' murmured the animal. 'I've been exercising it and eating plenty of grain, so there's a lot of good meat there.'

    It gave a mellow grunt, gurgled again and started to chew the cud. It swallowed the cud again.

    'Or a casselore of me perhaps?' it added.

    'You mean this animal actually wants us to eat it?' whispered Trillian to Ford.

    'Me?' said Ford, with a glazed look in his eyes, 'I don't mean anything.'

    'That's absolutely horrible,' exclaimed Arthur, 'the most revolting thing I've ever heard.'

    'What's the problem Earthman?' said Zaphod, now transfering his attention to the animal's enormous rump.

    'I just don't want to eat an animal that's standing there inviting me to,' said Arthur, 'It's heartless.'

    'Better than eating an animal that doesn't want to be eaten,' said Zaphod.

    'That's not the point,' Arthur protested. Then he thought about it
    for a moment. 'Alright,' he said, 'maybe it is the point. I don't
    care, I'm not going to think about it now. I'll just ... er ... I
    think I'll just have a green salad,' he muttered.

    'May I urge you to consider my liver?' asked the animal, 'it must be very rich and tender by now, I've been force-feeding myself for months.'

    'A green salad,' said Arthur emphatically.

    'A green salad?' said the animal, rolling his eyes disapprovingly at Arthur.

    'Are you going to tell me,' said Arthur, 'that I shouldn't have green salad?'

    'Well,' said the animal, 'I know many vegetables that are
    very clear on that point. Which is why it was eventually
    decided to cut through the whoile tangled problem and breed
    an animal that actually wanted to be eaten and was capable of
    saying so clearly and distinctly. And here I am.'

    It managed a very slight bow.

    'Glass of water please,' said Arthur.

    'Look,' said Zaphod, 'we want to eat, we don't want to make a meal of the issues. Four rare stakes please, and hurry. We haven't eaten in five hundred and sevebty-six thousand million years.'

    The animal staggered to its feet. It gave a mellow gurgle. 'A very wise coice, sir, if I may say so. Very good,' it said, 'I'll just nip off and shoot myself.'

    He turned and gave a friendly wink to Arthur. 'Don't worry, sir,' he said, 'I'll be very humane.'

    It waddled unhurriedly off to the kitchen.

  5. Re:Where is the line? by Anonymous Coward · · Score: 5, Funny

    And what about the humans who don't contemplate the meaning of life? Most of us don't contemplate the meaning of life every minute of our lives.

    We do actually. Look, there's no easy way to tell you this but it's time you knew; you're one of the mice.