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US Finalizes Stem Cell Research Guidelines

An anonymous reader writes with an excerpt from Cosmos Magazine, to wit: "The US government unveiled final rules for embryonic stem cell research, laying out ground rules for 'ethically responsible, scientifically worthy' studies eligible for federal funds. The new rules, which go into effect today, follow President Barack Obama's March 9 executive order lifting a ban on embryonic stem cell research, an order that went into effect under his predecessor, George W. Bush. ... The US National Institutes of Health's (NIH) guidelines are slightly less restrictive than those outlined in a draft document released in April in that they allow the use of existing stem cell lines, in addition to new ones derived from IVF procedures. ... The NIH received some 49,000 comments from patient advocacy groups, scientists, medical groups, and other interested parties before issuing the guidelines."

37 of 249 comments (clear)

  1. Existing lines by JobyOne · · Score: 3, Insightful

    I've never understood the opposition to using existing stem cell lines for research.

    Assuming there is a moral problem with destroying embryos, the damage is done. At this point you're pretty much saying "don't eat that cow" when the cow is already dead. Once it's dead you can either eat the cow and have a delicious steak or waste the cow and let it rot.

    Same thing with a stem cell. Once the embryo is destroyed you can either waste it...or maybe find ways to cure a zillion diseases. Either way the embryo is still dead.

    --
    Porquoi?
    1. Re:Existing lines by NecroPuppy · · Score: 4, Insightful

      The point is that if the bans were there, then the embryos wouldn't be destroyed in the first place.

      This, of course, ignores comepletely that most embryos held by fertility clinics (and other sources) are ultimately destroyed anyway.

      My view is simple: Why not recycle? If another use can be found for them, great. If not, that's fine too.

      --
      I like you, Stuart. You're not like everyone else, here, at Slashdot.
    2. Re:Existing lines by muridae · · Score: 2, Interesting

      The fear, rational or not, that seems prevalent in those with a 'conservative' mindset is not that the embryos are going to waste, but that if the discarded embryos are going to be used for stem cells it may encourage doctors to create many more than they need. That IVF happens may be something that individuals agree or disagree with, but there is a general disagreement with encouraging doctors to create even more extras.

    3. Re:Existing lines by NecroPuppy · · Score: 4, Interesting

      Actually, with IVF, many embryos are normally grown simultaniously, with only the best two or three candidates considered for implantation.

      Given the inherant dangers of the egg harvesting procedures, it is unlikely that any ethical doctor would purposefully subject a woman to that, just for the purpose of additional stem cell lines.

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      I like you, Stuart. You're not like everyone else, here, at Slashdot.
    4. Re:Existing lines by ArcherB · · Score: 2, Interesting

      I've never understood the opposition to using existing stem cell lines for research.

      Assuming there is a moral problem with destroying embryos, the damage is done. At this point you're pretty much saying "don't eat that cow" when the cow is already dead. Once it's dead you can either eat the cow and have a delicious steak or waste the cow and let it rot.

      Same thing with a stem cell. Once the embryo is destroyed you can either waste it...or maybe find ways to cure a zillion diseases. Either way the embryo is still dead.

      The problem many have is that in order to extract stem cells from an embryo, you have to coax it into starting to grow and mature. At this point, it no longer becomes a single cell fertilized egg, but a developing embryo, zygote, baby or whatever you want to call it, that you have to destroy to "harvest" stem cells from it.

      IMHO, there are way too many other methods to get new stem cell lines that are more useful and do not involve the destruction of any human life at all to even consider extracting new embryonic stem cells. The scientist that discovered the methods for extracting embryonic stem cells agrees with me (read my sig). The only point in harvesting new embryonic stem cell lines is to jab a thumb in the eye of "pro-lifers" and to try to remove any legislation that shows any respect at all for the unborn. "Pro-choicers" have a constant fear that legislation that provides any protection for the unborn is a step toward making abortion illegal.

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      There is no "I disagree" mod for a reason. Flamebait, Troll, and Overrated are not substitutes.
    5. Re:Existing lines by ArcherB · · Score: 4, Interesting

      The anti-stem cell research, anti-abortion, and anti-sex education positions of conservatives is primarily motivated by sin.

      Is there a fallacy of stereotyping? Doesn't matter. Let me give you some advice: If you don't know what you are talking about, shut up. As a conservative, allow me to correct you and alleviate your ignorance.

      Some of us conservatives are against embryonic stem cell research because it is killing human life for research purposes. I know, it's only a few cells, so it doesn't count right? So, tell me then, when do human beings earn the right to not be destroyed and experimented on? Is it at birth? Is it after the first trimester? How about voting age? Don't have an answer? Me neither. That's why I'm "conservative" in my answer and simply say, "NO RESEARCH ON HUMANS WITHOUT THEIR CONSENT, PERIOD!"

      Is the right to not be experimented on so unimportant that you guess when people get this right?

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      There is no "I disagree" mod for a reason. Flamebait, Troll, and Overrated are not substitutes.
    6. Re:Existing lines by ppanon · · Score: 4, Insightful

      So, tell me then, when do human beings earn the right to not be destroyed and experimented on?

      There's a few possible candidate thresholds but, when it comes to destruction, the ones that make the most sense are:

      1. "self-sustaining" viability outside the womb (currently around 22 weeks gestation) or
      2. significant nervous system complexity (somewhere between 9 to 20 weeks).

      Experimentation is a much broader issue with many more possible scenarios and lots of grey areas. That said, I can't see a significant ethical problem with experimentation if you're dealing with individual cells for therapeutic purposes.

      As someone else pointed out, there may be significant ethical issues in how you obtained the embryos or eggs due to the risk it poses to the donor. I think some totalitarian state having "farms" with captive unwilling donor women to produce embryos for export to Western hospitals is definitely a scenario we would want to prevent through legislation, and the source tracking as with the current legislation should address that.

      To use your example, experimenting with cells from low-division embryos is not significantly different from experimenting with skin or bone marrow cells. You don't have a problem with donating a few skin cells because, with a local anaesthetic, you wouldn't even feel it. On the other hand, if someone endangered your life by ripping 50% or more of your skin off for stem cell material, I expect you would be pretty upset. Conversely, an undifferentiated embryo has no nerve cells to feel, know, or want anything.

      Certainly, if successful embryonic stem cell therapies actually get developed, then there will be an issue with supply vs. demand and access criteria. That said even if we don't find an ethically satisfactory technical solution for solving the supply scarcity problem, we've already got a similar issue with a limited supply in the case of organ transplants. Yet there doesn't seem to be a credible broad movement arguing for the cessation of organ transplants.

      --
      Laissez lire, et laissez danser; ces deux amusements ne feront jamais de mal au monde. - Voltaire
    7. Re:Existing lines by ArcherB · · Score: 3, Insightful

      Thank you for a well thought out, fair minded response. However, there are some points I have issue with:

      "self-sustaining" viability outside the womb (currently around 22 weeks gestation) or

      A newborn is not "self-sustaining". Hell, I know a few 30-year olds that are not "self-sustaining". What about premature babies that require incubation? They are not "self-sustaining". Are they available for experimentation?

      Also, embryos in a petri dish can survive outside the womb about as long as newborn.

      significant nervous system complexity (somewhere between 9 to 20 weeks).

      9 to 20 weeks is a big range. I'm guessing you are setting it so broad because you don't know. I don't either. Let's just say it's 14 weeks, 3.5 days. What about the baby that is 14 weeks, 2 days? Some babies mature at different rates than others. How do you know which babies have a nervous system? What happens in 20 years if we find out that embryos can feel pain without a nervous system? My point is that too many times, we've thought "things" couldn't feel pain or were labeled as not or less-than human with horrific results. We should have learned by now that man is not perfect enough to decide who deserves basic rights or what is human.

      To use your example, experimenting with cells from low-division embryos is not significantly different from experimenting with skin or bone marrow cells.

      Right. Under a microscope, they are pretty much the same thing. The difference is the donor and what damage it does to the donor. You mentioned skin and bone marrow. I have both. If I want to donate tissue or take part in a scientific experiment, I am free to do so (and I have). If you can find an embryo that will consent to experimentation, then I guess that's OK too. But even with parental consent, I don't feel that parents have the right to give permission to anyone to kill a child for the purpose of experimentation. And would it even be legal for me to volunteer for an experiment when the end result is certain death? It certainly wouldn't be legal to hold such an experiment.

      The other point is that donating a few cells won't kill me. Embryos are destroyed in the process of harvesting cells. If you could harvest stem cells while not killing the embryo, then I wouldn't really have a problem with it, provided you have the parent's permission.

      Certainly, if successful embryonic stem cell therapies actually get developed, then there will be an issue with supply vs. demand and access criteria.

      So far, all the therapies that have been developed have come from adult derived stem cells. There will be no shortage of those as they can be taken directly from the patient.

      And, it's nothing like an organ donor. Even as you mentioned before, it's no big deal giving a cheek swab or skin sample. Giving up a liver is nothing like giving a blood, marrow, or skin sample. Something about organs make them a requirement to life. Skin samples? Not so much.

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      There is no "I disagree" mod for a reason. Flamebait, Troll, and Overrated are not substitutes.
    8. Re:Existing lines by ArcherB · · Score: 2, Interesting

      Oh and your sig is 100% pure bullshit. It should read: "If embryonic stem cell research makes you uncomfortable, you're an unthinking hopelessly ignorant idiot."

      Wow! This AC just called the pioneer of embryonic stem cell research a "hopelessly ignorant idiot." WOW! The irony is too thick to cut!

      Here's the whole quote:

      "If human embryonic stem cell research does not make you at least a little bit uncomfortable, you have not thought about it enough"

      -- Dr. James Thomson, pioneer of embryonic stem cells

      Don't take my word for it. Google the quote.

      Let me reiterate that this AC just called Dr. James Thomson, THE pioneer of embryonic stem cell research, "an unthinking hopelessly ignorant idiot."

      --
      There is no "I disagree" mod for a reason. Flamebait, Troll, and Overrated are not substitutes.
    9. Re:Existing lines by HellYeahAutomaton · · Score: 2, Interesting

      Perhaps because you haven't thought of the consequences of the deep bioethical debates behind it. I preface this by stating that I am a fan of regenerative technologies and think a great deal of good can and will come out of them in time.

      Eugenics is a sinister topic that deserves a great pause. There are several key issues and parallels at play:

      1) Treatments that increase the quality of life effect the population as a whole in mortality rates, and what established medical industries will it harm?
      2) Possibilities this work lead to genetically superior "super men" , opening the pandora's box to designer babies and other man-made chimeras and monsters.
      3) Life devaluation issues ex: Will people start blending up of lower class/poor/minority babies just to get their stem cells because life has become so "cheap" and abundant?
      4) Can we label anyone a "volunteer" for anything that we want to do research on?

      Oddly enough this is one thing that Bush got right for all the wrong reasons. He was correct in giving some time for the application of unproven technologies to sink in and let society stew a little on the ramifications.It was important for him to pick a side and get people to polarize their opinions to help along the public policy.


      "Either way the embryo is still dead."

      As a species, we have a certain amount of respect for our dead, whether or not you agree with it. There are laws on the books about how the dead must be prepared for burial, how casket vaults must be made around coffins to prevent the ground from sinking. Grave robbing laws came about because of the high demand for understanding anatomy by means of dissection. For a human grave we treat it with respect and attempt to protect it from desecration. Organ donation as a choice has evolved as an important act of volunteerism. One really big reason that people take issue with using a dead embryo is because they were not sentient volunteers acting on their own free will -- hence making them victims, and then adding insult to injury. Whether or not you believe them to be victims doesn't matter nearly as much as the idea that *someone else* might, and throw roadblocks up to block your agenda. There are people out there who believe that the means needs to justify the ends.

        I've read many books on eugenics,genetics, and bioethics over the years but none of them stands out so nearly as well as
      When Medicine Went Mad I've been spending several months absorbing the debates and came to the conclusion that it is extremely important in terms of public opinion to do your research in such a way that is ethical, professional, and will not raise doubts or fears about the means in which your data is acquired to preserve and maintain the public trust.

    10. Re:Existing lines by Omestes · · Score: 4, Insightful

      Jumping in here...

      A bit of background, I am an atheist, and I am against abortion (except in the cases where the mother could die). I am not against stem-cell research though, because the cells were already extracted, and would be destroyed if otherwise not used. If every cluster was brought to term (an absurdity), then I would be against stem-cell research as well.

      The reason I stated I am an atheist is to make it perfectly clear that I don't have an idea of sin, or "ensoulment" involved here, basically this is ethical and not a moral judgment. I bring up my opposition to abortion, because these are related issues, and I am for stem-cell research for the same reasons I am against abortion, and have the same caveats to my support as I do my opposition.

      I also agree with the person above you; the "humanity" of an embryo is determined by its neurological properties. Without a brain, or a nervous system above a certain threshold of complexity, you cannot be considered to be human, much less sencient. The caveat here is potential, an embryo may be a person someday, and this must be weighed as well. In the case of abortion, the odds of fulfilling this potential is rather high left to its own devices, wherein the case of stem-cells the odds of reaching the point of being human is completely nill. The cells that we use for research will NEVER turn into people left to their own devices, and thus their potential is much much lower than an organic (in utero) cell mass.

      We must weigh the potential here. Being a human is obviously the most important, but we must also balance this with the utility to science, and the well-being of humanity as a whole.

      The caveat here is that I will not inflict these opinions on anyone, this should be the choice of the parent or donor. I say this because I am pretty sure I don't know any better than any other person, much less the people effected by these decisions. While being against abortion, I still am pro-choice, as I am towards stem-cells.

      If you have a brain-dead dependent, you, granted power of eternity, can pull the plug. This should be no different for undeveloped cell masses in deep freeze. The donor should choose the fate. Not a bunch of self-righteous asses such as me and you (or really anyone else).

      --
      A patriot must always be ready to defend his country against his government. -edward abbey
    11. Re:Existing lines by interactive_civilian · · Score: 4, Informative

      A few things:

      A newborn is not "self-sustaining". Hell, I know a few 30-year olds that are not "self-sustaining". What about premature babies that require incubation? They are not "self-sustaining". Are they available for experimentation?

      Also, embryos in a petri dish can survive outside the womb about as long as newborn.

      I suspect that the GPP was saying "self-sustaining" as in "able to survive without being directly attached to the mother's life support". A newborn can obtain oxygen and get rid of carbon dioxide and other metabolic waste without having to be connected via an umbilical to the mother. One's take on that kind of alters the scape of your other questions. A premature birth can survive, grow, and develop without being directly attached to the mother's life-support. An embryo in a petri dish cannot, as we do not have the technology or knowledge to artificially replicate a womb.

      significant nervous system complexity (somewhere between 9 to 20 weeks).

      9 to 20 weeks is a big range. I'm guessing you are setting it so broad because you don't know.

      Again I am assuming the GPP used such a big range for a number of reasons: different individuals will develop at different rates, different people will disagree what constitutes "significant nervous system complexity", etc. Therefore your example using an exact time measurement is inapplicable.

      What happens in 20 years if we find out that embryos can feel pain without a nervous system? My point is that too many times, we've thought "things" couldn't feel pain or were labeled as not or less-than human with horrific results. We should have learned by now that man is not perfect enough to decide who deserves basic rights or what is human.

      This is a nonsense question. To "feel pain" you need three things: 1.) a sensor to detect damage, 2.) a transmission system to send that information to 3.) a processor to interpret that data. In mammals, this requires a nervous system. It is part of our biology. No nervous system, no pain.

      May I ask a question: are you against In Vitro Fertilization? In such situations, as has been mentioned numerous times, several eggs are fertilized, a select few most viable embryos are selected for implantation, while all others which may or may not be viable are destroyed. Is this murder in your eyes? I'm not trying to jump on your case, I'm just trying to gauge your consistency.

      --
      "Empathise with stupidity, and you're halfway to thinking like an idiot." - Iain M. Banks
    12. Re:Existing lines by ppanon · · Score: 2, Insightful

      You basically got it all right. I deliberately put "self-sustaining" in quotes as an acknowledgement that premature babies, while developing independently of maternal placental support, may still need significant technological support (usually due to poorly developed lungs). I left the time range for nervous system complexity open for both reasons: an uncertainty in the actual appropriate level of nervous system complexity (insufficient data - we'll have a better idea after we develop Artificial Consciousness), as well as possible individual developmental variations (although the first criteria dominates the current error range).

      And yeah, while consideration of the impact on donors is one of many important ethical considerations, the most important phrase in that whole post regarding the ethics of embryonic stem cell research is: an undifferentiated embryo has no nerve cells to feel, know, or want anything. If the belief that an embryo has a soul helps someone get to sleep at night in case they should die before they wake, then that's fine. But they can keep their unsubstantiated beliefs to themselves and out of medical/scientific ethics discussions. There are a lot of good reasons for keeping a strong ethical leash on human medical research, but that's not one of them.

      --
      Laissez lire, et laissez danser; ces deux amusements ne feront jamais de mal au monde. - Voltaire
    13. Re:Existing lines by HungryHobo · · Score: 2, Insightful

      I'm all for stem cell research but the "human DNA is only slightly different from animal DNA so why not treat them the same" argument leads to HumanMcNuggets and HumanBurgers

  2. How many lives have been lost? by QuantumG · · Score: 5, Insightful

    During the 6 years that this has been banned how much research into life saving treatments has been delayed? How many living, breathing, people have been denied these treatments? How many more will die over the next 10 years that could have been saved?

    And all to placate the extreme pro-life fringe, who count fertilized embryos (that would be destroyed anyway) as sacred, and the ignorant who continually refer to "aborted fetuses" whenever the subject comes up.

    For shame.

    --
    How we know is more important than what we know.
    1. Re:How many lives have been lost? by CrimsonAvenger · · Score: 3, Insightful

      During the 6 years that this has been banned how much research into life saving treatments has been delayed?

      Probably none at all. It's not like the "ban" prevented research, it just prevented Federal funding for research. And it didn't even really prevent that, as long as you were willing to abide by Federal rules.

      BLOCKQUOTE>How many living, breathing, people have been denied these treatments?

      Zero. Latest guesstimates I've seen say it'll be 20 years minimum before any of these treatments get all the way through clinical trials to general use. So none of them would be ready for use today, even if we'd started six years back.

      How many more will die over the next 10 years that could have been saved?

      Zero. See above. If we'd started six years ago, best guess says we'd have no usable treatments for another 14 years.

      Again, note that President Bush's "ban" wasn't actually a ban. It wasn't even a ban on Federal funding (for that, we have to drop back to Clinton's Presidency, when no Federal funding for stem cell research was available at all).

      Was Bush's "ban" a good thing? I doubt it, myself, but it's arguable.

      Would we be better off if it had not been done? No, since absent his "ban", we'd have been operating under the old rules (which WAS a ban).

      Would we have these miracle cures available now? No. Clinical trials take much longer, especially when we're dealing with "treatments" that might give us novel new cancers.

      Would they be available soon? It'll be a bloody miracle if I live that long, but then I'm an old guy with cancer.

      Would they be available SOONER? Probably. Probably not soon enough to do anything for me, even assuming they'd fix what I have.

      --

      "I do not agree with what you say, but I will defend to the death your right to say it"
  3. Bad Summary by CorporateSuit · · Score: 4, Informative

    There was no ban on embryonic stem cell research. There was a ban on the federal government using tax dollars to fund embryonic stem cell research.

    --
    I am the richest astronaut ever to win the superbowl.
    1. Re:Bad Summary by NecroPuppy · · Score: 4, Interesting

      Which, for more than a few labs or research centers, was effectively a ban.

      While some locations were able to get private funding (and thus get around the relatively useless lines approved by the Bush govt), this sort of blue sky health research has generally seen a lot more money from the government.

      Because of that ban, for example, DARPA couldn't effectively spend money on research into experimental treatments for spinal cord injuries involving stem cells. Now they can. And, quite likely, will.

      --
      I like you, Stuart. You're not like everyone else, here, at Slashdot.
    2. Re:Bad Summary by jo_ham · · Score: 5, Insightful

      It was effectively a ban, since if you ran any privately funded stem cell research in the same labs as any work (even with nothing to do with stem cells), the federal funding would be withdrawn for that research.

  4. There was never a ban on research by Anonymous Coward · · Score: 2, Informative

    Why do people refuse to get this right? There was never a ban on embryonic stem cell research, just a ban on federal funding of such research... Geesh. Personally, I wish there was a ban on a lot more federal funding of a lot more things. If our politicians would actually READ the Constitution and abide by it, maybe we wouldn't even be having this discussion.

  5. Let's be accurate here. by caladine · · Score: 4, Informative

    The new rules, which go into effect today, follow President Barack Obama's March 9 executive order lifting a ban on embryonic stem cell research, an order that went into effect under his predecessor, George W. Bush. ...

    In the interest of accuracy, I wish people would stop calling it a "ban on embryonic stem cell research".

    While calling it a all out "ban on embryonic stem cell research" makes a great sound bite, it's horribly inaccurate. It was only a ban on federal funding for embryonic stem cell research for stem cell lines created after August 9, 2001. If you were willing to fund it yourself, you were free to do so. Bush's executive order didn't change that part at all which the misleading sound bite alludes to.

    Now, with that interjected, back our regularly scheduled flame wars on this topic.

    1. Re:Let's be accurate here. by QuantumG · · Score: 3, Informative

      Understand this, any institution that took federal funding for any research was banned from doing stem cell research.. so basically what you're saying is that they should have started a completely new lab, separated themselves from the rest of their scientific community, to do underfunded research. Well obviously they're just whiners.

      --
      How we know is more important than what we know.
    2. Re:Let's be accurate here. by interkin3tic · · Score: 3, Informative

      Corporations set up separate legal entities all the time to mitigate liability.

      If we were talking about a paper issue that would be great, assuming researchers could afford the cadre of lawyers that corporations use (which they can't). But we're actually talking about physical labs, not imaginary companies.

      What exactly was stopping them from using the existing stem cell lines? I don't believe I've ever received a satisfactory answer for this other then "They just couldn't!"

      Some labs may have been heavily invested in a line of stem cells created after that date. For example, switching to another cell line is incredibly wastefull if you've already spent millions on microarray analysis of a new stem cell line that happened to have been made after the magic date.

      Some necessary stem cell lines have not yet been created. If you want to study an inherited disease, say one that causes brains to be malformed, you might want to study how neurons differentiate. Generating a stem cell line from an embryo that would have that disorder would be more convinient, not to mention more humane, than having carriers of the disease continually reproduce and harvesting the fetuses after they've started growing brains.

      There's no guarantee that the existing stem cell lines are good for all things that ESC could be used for.

      And it's an artificial distinction that pointlessly limits research in a developing field. If you have an ethical problem with ESC, using existing lines is still problematic. If not, there's no reason for the ban.

      Not an exhaustive list, and I think if you searched there are plenty of people who have better answered questions like yours.

    3. Re:Let's be accurate here. by ring-eldest · · Score: 4, Insightful

      A "ban on federal funding for X, Y, and Z" is effectively a ban on X, Y, and Z.

      Take abstinence only sex-education for example. I'm not sure what the current situation is, but for a long time schools either taught abstinence only sex ed (no instruction about condom use. No mention of birth control at all, unless it paints the users as morally bankrupt) or they had to stop taking certain funds from the state and federal government. There aren't too many school boards that will vote to turn down money... Even if it hurts the kids.

      If you control the purse strings, you control the outcome. Are you surprised people see this as a ban?

    4. Re:Let's be accurate here. by argStyopa · · Score: 2, Insightful

      ...nor did Bush's executive order have any impact on funding for such research in any other country, yet THEY haven't produced any of the purported and inevitable 'miracle' cures in the meanwhile....

      So either:
      - the assertion that embryonic stem cells were critical to medical breakthroughs and that the lack of Federal funding has caused people to die from otherwise treatable conditions was just politically-motivated hyperbolic bullshit, or
      - every other country in the world is incompetent in the field of stem cell research, and unless US researchers using government dollars are able to find the use for stem cells, nobody will.

      Go ahead, pick one.

      --
      -Styopa
  6. NEVER WAS BANNED! by thejuggler · · Score: 2, Informative

    "President Barack Obama's March 9 executive order lifting a ban on embryonic stem cell research, an order that went into effect under his predecessor, George W. Bush. "

    President Bush DID NOT ban embryonic stem cell research. He did limit Federal money to only the existing lines of embryos that had already been created at the time. No new money was to be spent on creating new embryo lines.

    The fact remains President Bush was the first President to ever Federally fund embryonic research.

    BTW: Far better research is being done with adult stem cells and there are actual cures and treatments in testing or completed. http://www.stemcellresearchfacts.com/cures_failures.html

    1. Re:NEVER WAS BANNED! by darkmeridian · · Score: 5, Insightful

      Your entire post is misleading. President Bush was the first President who had to make a decision regarding stem cells. He limited federal funds to existing adult stem cells because of misplaced moral considerations. The embryos would have been destroyed by the fertility labs anyway, but when signing the bill, Bush was flanked by children conceived from embryos. There was no scientific reason to limit the federal funding. It's not even clear the moral justification was that great, either.

      After Bush crippled competing research, it's no wonder that adult stem cells are ahead in the race. Imagine what would have happened if stem cell research was not limited out of political considerations.

      --
      A NYC lawyer blogs. http://www.chuangblog.com/
    2. Re:NEVER WAS BANNED! by jo_ham · · Score: 2, Insightful

      FALSE.

      Adult stem cells are useful, but ultimately nowhere near as effective as embryonic lines. The science of this is well understood. The site you linked to there is a shill site that isn't really science, and is just designed to muddy the waters and try to convince people without a science background that what they say is "fact" when really it's just cloaking the agenda it's trying to push (that killing embryos is wrong).

      Bush *effectively* banned stem cell research by attaching some really petty, nasty limitations of federal money to *any* research (not just stem cells, not just biology even) in an institution that went ahead and found private funding for research on new cell lines. Even if they did this research with no federal money, all of the federal money for *all other programmes* would be removed because of it.

      So, the choice was funding the research privately and doing without any federal money *for any scientific research whatsoever*, or not doing it. Or setting up an entirely new lab just for the stem cell work (very expensive and silly).

    3. Re:NEVER WAS BANNED! by interkin3tic · · Score: 2, Interesting

      Far better research is being done with adult stem cells and there are actual cures and treatments in testing or completed.

      You wonder then why so many researchers at premier institutions are trying to study ESC when such credible sources as stemcellresearchfacts.com could tell them they're dead ends. I mean, it has FACTS right in the title!

      I bet they the research will never lead anywhere so they can keep the gravy-train of state grants coming.

      Sarcasm aside, no, the above statment is as wrong as you'd expect from such a biased source. hESCs are being used as research models in labs currently. If you want to study cell differentiation for example, you need to be studying some type of ESC. Studying embryonic cells maturing into, say, neurons will tell you something about how that happens naturally.

      If you only care about applied research and think basic science research is worthless, you're in the wrong corner of the internet, and you should also keep in mind that embryonic stem cell research has already given us induced pluripotent stem cells, which are more promising for treatments than adult stem cells OR embryonic stem cells.

  7. Re:At last!!! by Nathrael · · Score: 2, Funny

    And when we finally found out how to cure them, maybe we could cure the Democrats as well!

    --
    A good education is a bit like a STD - it makes you unsuitable for a lot of jobs and gives you a desire to spread it.
  8. Re:Waste of resources either way by CorporateSuit · · Score: 2, Interesting

    You put it extremely crudely, but this is more a problem than most people realize. Hospitals are not a strong business. They lose money on a lot of cases because the current costs of treating patients are ridiculous, and many insurers refuse to pay such costs - so the hospital swallows it. The most common surgery, cataract removal, typically costs its hospital thousands more to perform than they get paid, and they can't just turn the patients away. It's not all going to filthy-rich doctors and their heated pools. So many physicians are being sued for malpractice in some MSAs that the definition of "malpractice" has lost all meaning. I learned from my father (rated the 2nd best physician in the state, at what he did, when he was in practice) that there's more money in being a 100K-a-year engineer than a 400K-a-year physician -- and a much less-stressful life to live.

    New technology means better healthcare means more costly healthcare means we either A) Cannot treat everyone or B) must reduce the quality of healthcare we are dispensing to sustainable levels. If these sciences find cheaper ways to fix a broken hip or perform a bicuspid valve replacement then they will aid society. If they simply come up with more expensive (albeit better) ways of current healthcare we have, then we're only digging the hole deeper. When it's 100 times cheaper to give you a 90% chance to live than to give you a 91% chance to live, they are typically compelled to spend 100 times more -- and who is going to pay for that?

    --
    I am the richest astronaut ever to win the superbowl.
  9. Discrimination against human-animal hybrids by greenreaper · · Score: 4, Funny

    Speaking as a furry, I'm disappointed in section IV of the guidelines. Who will give us our fluffy tails, or make Piccinini's disturbing sculptures a reality now? At this rate I might as well just buy my own island and experiment there . . .

  10. Answers to a couple of questions by Anonymous Coward · · Score: 2, Interesting

    Someone asked why on earth anyone would object to embryos being used for research - since they would be destroyed anyway.
    .
    The best way I can answer this is to ask why we don't take organs when people on death row are executed. The people are going to die anyway, so why not take their organs and use them for someone else's benefit.
    .
    I think the answer to this question is that are afraid that juries might be more likely to pass the death penalty if they are aware that there is a potential benefit to other people from the death of the prisoner. This might not be a conscious thought, but lets say you were 95% sure that the person was guilty, but you weren't totally sure. If you knew that the organs would be used to help someone else, you might think - "Hey, I'm pretty sure this person is guilty, and even if he (or she) isn't guilty, at least someone will benefit."
    .
    For those who think that embryos have a moral value, it is never right to use them as a means to an end. Using them (and destroying them), even for a good purpose, devalues them.
    .
    I know that many folks won't agree with that, and that's ok. I just wanted you to understand why people don't want them used for another purpose, even if they will be destroyed anyway.
    .
    The second thing I wanted to bring up is that researchers have discovered ways to "reprogram" cells, so that adult cells can be made to behave like embryonic stem cells. (See http://www.sciencedaily.com/releases/2009/02/090227112303.htm) Furthermore, any therapies based on this technique could lead to new organs or tissues that are an exact DNA match for the patient, which would probably eliminate the risk of organ rejection. As I said, these reprogrammed adult cells seem to have all of the characteristics of embryonic stem cells, which means that there may no longer be any scientific need to use embryonic stem cells. In that case, the reverse of the ban could just be a cheap political ploy to devalue the embryo and to make Bush look bad - even though there is not scientific benefit. (I agree that more research may be necessary to make sure that the reprogrammed adult cells do indeed have all of the same capabilities as embryonic stem cells).
    .
    Finally, I have to point out that even though Obama claimed to eliminate the false choice between ethics and science, he still implemented some ethical rules - specifically a ban of reproductive cloning. I happen to agree with this, but I thought it was disingenuous of him to pretend to get rid of ethical barriers that restricted science. All he did was eliminate the barriers that he disagreed with and retain the barriers that he did agree with. He had the right to do that, of course - he is the president - I just wish that he had spoken more clearly about what he was doing.
    .
    In fact, I think this whole debate suffers from major political posturing. I think that most American are completely unaware of the advances that I wrote about earlier - for the reprogramming of adult stem cells. If people were aware that there was a valid alternative to embryonic stem cells, I think there would be much less support for the destruction of embryos. Even if you aren't pro-life, I would guess that if you had two equal choices - one which destroyed an embryo, and one which did not - then you would pick the one that did not destroy the embryo.
    .
    I have probably written too much already. In addition to all of that, I just want to say that I hope that all of the folks who are desperately waiting for cures are able to find some help from the research. I just wish that it didn't have to come at the expense of an embryo.

  11. That's how it goes with tax funding. by jcr · · Score: 2, Informative

    Anytime an activity is funded involuntarily, it's going to be a political issue. This is the case whether we're talking about whether or not to fund medical research, or whether to teach science or religion in public schools.

    The moral question here isn't whether stem cell research will lead to life-saving cures or whether it's killing babies, the question is whether it's OK for the federal government to take money from us forcibly, and then spend it on any activity that's not within its enumerated powers that we granted to it in the constitution.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
  12. Re:Here we go again... by jcr · · Score: 2, Informative

    Try reading it. There are 17 enumerated powers. Controlling medical research and turning our lives into political issues isn't among them.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
  13. Re:Here we go again... by jcr · · Score: 2, Informative

    Don't fetishize that document like it's the Gospel

    It's not a work of fiction like the bible, it's a contract. It is the entirety of the legal basis for the power of the federal government.

    I'm more along the lines of "Let them do it unless Article 1 Section 9 (or some other section)" says they can't.

    Read the tenth amendment.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
  14. Re:Here we go again... by jcr · · Score: 2, Informative

    Can't stand your "government shouldn't do much of anything [especially things I don't want it to do]" attitude, no matter what the reason for it is.

    It's called the rule of law, sunshine. If you want the government to do things outside the powers we've granted to it, then propose a constitutional amendment to allow it to do so. By merely ignoring the constitution, we get chaos.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."