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Human Sperm Produced In the Laboratory

duh P3rf3ss3r writes "The BBC is carrying a report from a team of researchers at Newcastle University who claim to have developed a the first 'artificial' human sperm from stem cells. The research, reported in the journal Stem Cells and Development, involved selecting meristematic germ cells from a human embryonic stem cell culture and inducing meiosis, thus producing a haploid gamete. The authors claim that the resulting sperm are fully formed, mature, human sperm cells but the announcement has been greeted with mixed reaction from colleagues who claim the procedure is ethically questionable and that the gametes produced are of inferior levels of maturation."

26 of 368 comments (clear)

  1. I SWEAR by Phizzle · · Score: 4, Funny

    I DIDNT DO IT!

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    1. Re:I SWEAR by MyLongNickName · · Score: 4, Funny

      I DIDNT DO IT!

      This is Slashdot. That goes without saying.

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  2. So what? by Anonymous Coward · · Score: 5, Funny

    What's the big deal? I generate human sperm at least once a day and I don't even need a laboratory.

    1. Re:So what? by LordKaT · · Score: 4, Funny

      I have a lab and he *HATES* it when I try to generate sperm.

    2. Re:So what? by cashman73 · · Score: 5, Insightful

      Or, 3. if they took stem cells from a lesbian, they could generate some sperm for her, thereby along her to impregnate her other female partner. Next, all they need to do is to generate an egg cell from a homosexual male stem cell. Then, once same-sex couples can successfully reproduce, the religious right is going to go apeshit and all hell is going to break loose! ;-)

    3. Re:So what? by ElKry · · Score: 5, Interesting

      And, on a chilling (for me) twist, if they took stem cells from a woman, they could generate some sperm for her, thereby allowing her to impregnate herself .

    4. Re:So what? by interkin3tic · · Score: 4, Funny

      Wow. Incest++. That's a term that I had hoped would never be invented.

    5. Re:So what? by interkin3tic · · Score: 5, Interesting

      Sperm doesn't have pairs of chromesomes, it has only one. But you're right, if you make sperm from female stem cells it could only have an X chromesome, never a Y chromesome, so you'd only get female offspring.

      The only inherent loss of genetic diversity would be the Y chromesome, which doesn't have much genetic information on it anyway. The wiki page on the Y chromesome points out that "the human Y chromosome itself contains only 78 working genes, compared to close to 1500 working genes on the X chromosome" and none of the 78 are "vital." For women anyway for obvious reasons.

      As long as the female that the sperm are derived from isn't closely related to the female that produces the egg, it wouldn't seem like there would be diversity loss.

  3. Mandatory... by Anonymous Coward · · Score: 4, Insightful

    I for one, welcome our female overlords. I hope they find me useful and will not use me for food.

    1. Re:Mandatory... by Nadaka · · Score: 4, Funny

      speak for yourself, I don't mind if I she swallows.

  4. Misread by StDoodle · · Score: 5, Funny

    Is it any surprise that, with such an article, I had to do a double-take to properly read "...inferior levels of maturation."

  5. Re:Where's the story? by Vectronic · · Score: 4, Informative
  6. It's about time... by Tenek · · Score: 5, Funny

    Finally, this will address the critical shortage of sperm we face today.

  7. This story is just too hard to swallow! by Anonymous Coward · · Score: 5, Funny

    I couldn't resist.

  8. Re:Sperm Shortage? by f8l_0e · · Score: 5, Insightful

    Consider a man a wife. The husband is infertile for reasons other than motility. They could now have a child with sperm produced from his stem cells.

  9. Re:Wow science is amazing by Manfre · · Score: 4, Funny

    One step closer to not having hormonally imbalanced pregnant women...

    My wife and I really wish the human reproductive cycle involved external incubation. I'd create a device to post to twitter whenever the baby kicks.
     

  10. What's the problem? by Anonymusing · · Score: 4, Funny

    "the procedure is ethically questionable and that the gametes produced are of inferior levels of maturation"

    So... they're suitable for producing politicians, lawyers, and bad Slashdot comments?

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  11. Ok, let me be the first to say this... by RelliK · · Score: 4, Funny

    Every sperm is sacred.

    --
    ___
    If you think big enough, you'll never have to do it.
  12. Re:I can't believe it's not butter! by blueg3 · · Score: 4, Informative

    It actually turns out that's not true -- if you had nothing but the DNA sequence, you could not (even in theory) construct a human from it. For one, the mitochondria organelles have their own genetics independent of our own. The organelles are inherited directly from the mother's cells. For another, how DNA is used and rendered into proteins, etc. is altered by chemicals that are carried along with the cell. If those are stripped away, information is lost.

  13. Blood==Stem Cells==Babies????? by MarkvW · · Score: 4, Interesting

    If a woman gets your blood, then she can bear your children? Wow! This will be a great argument for deadbeat dads! Now they can truthfully say "I never had sexual relations with that woman."

    Black markets for the blood of rich men . . .
    Personal IP rights in your personal blood composition . . .

    Wow, the world got more interesting on 7/08/2009!!!!

  14. Re:Well... by schon · · Score: 4, Funny

    A man and a woman get into an elevator and press the button for the top floor. Halfway up, the elevator stops. The man picks up the emergency phone, and is told that they'll be stuck for at least an hour.

    The woman looks at him slyly and says "want to make me feel like a woman?"

    "Sure", the man says, immediately taking off his shirt.

    "Iron this for me!"

  15. One implication by Arthur+B. · · Score: 4, Insightful

    Interestingly, this opens the door to biological children from homosexuals couple. Sure it's been foreseen for a long time, still big big can of worm.

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    1. Re:One implication by thesandtiger · · Score: 4, Interesting

      Infertile heterosexual couples can't currently conceive children. This could grant that ability. That's huge. So how is the sexual orientation of the couple relevant?

      If the OP had said "This will allow people who couldn't have conceived the ability to have children, this opens up a can of worms" then sure - but he (and you) specifically mention the sexual orientation of the couples as being relevant. I'm just trying to understand why.

      Is it because gay people would be able to have children that share the dna from 2 same-sex parents? Is it because gay people having kids is an ethical concern? Is it squeamishness about gay folks being able to have children?

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  16. Re:Well... by mangu · · Score: 4, Funny

    I think we're safe for a while, until they manage to train the apes properly.

    What do you mean? I think we are pretty well trained right now!

  17. One upped by psychicninja · · Score: 5, Funny
    Man, this kind of beats the story I was just about to submit:

    Human Sperm Produced In The Lavatory

  18. Huge waste of tax dollars by Anonymous Coward · · Score: 5, Funny

    We give these scientists grant money to build labs to work on scientific discoveries. And they turn around and spend all day masturbating in the labs!