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Cure For Radiation Sickness Found?

Summit writes "A scientist has claimed to have discovered a radioprotectant that all but eliminates acute radiation sickness even in cases of lethal doses of radiation in tests on rats and monkeys, when injected up to 72 hours after exposure. They also claim the drug, a protein, has no observed negative effects in humans. They have not irradiated any people just yet, but if this turns out to be true, it could mean everything from curing cancer to making manned interplanetary space expeditions feasible... not to mention treatment for radiation exposures in nuclear/radiological accidents/attacks. If this drug works, it would mean a true breakthrough as past experiments with radioprotectants were not particularly promising in any respect." The only source for the story at this time is an exclusive in YNet News, a site with the subtitle "Israel At Your Fingertips." Such a radioprotectant would be huge news for Israel. Make of it what you will.

17 of 385 comments (clear)

  1. I doubt it... by Anonymous Coward · · Score: 4, Insightful

    No publication in a real scientific or medical journal.

    Further, radiation sickness is difficult to fix. You've got alpha, beta & gamma particles bombarding cells, causing damage all over the place. Chemical bonds are broken, energy is added, and new chemical bonds form.

    I really doubt a magic bullet can exist for the many types of cellular damage that can occur in different body systems.

    1. Re:I doubt it... by MightyYar · · Score: 3, Insightful

      Apoptosis did not evolve to combat massive doses of radiation. It's sort of a "blunt instrument", which takes out a lot of healthy tissue. Controlling apoptosis may very well allow recovery from radiation exposure. Perhaps there will be an increased cancer risk, but this is better than immediate death.

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      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  2. Oh good, by ChinggisK · · Score: 5, Insightful

    Now nuclear war won't be so bad.

    1. Re:Oh good, by Rogerborg · · Score: 4, Insightful

      MAD only applied when the enemy was a State. When it's a bunch of Peace Loving Religious cultists bashing lumps of plutinium together on a boat in New York Harbor, then survivability becomes an issue.

      --
      If you were blocking sigs, you wouldn't have to read this.
  3. Re:I need a car analogy... by Ihlosi · · Score: 3, Insightful
    Hell, it's early, so I may not be thinking correctly, but it seems to me like a little dose of this would go a long way to curing the horrible side effects of cancer treatment.

    And possibly make the treatment quite ineffective, if it also works on cancer cells.

  4. Re:YNet isn't the only one who's picked it up.. by Anonymous Coward · · Score: 4, Insightful

    Nice to see a second source.

    I was puzzled when I first read, "They also claim the drug, a protein, has no observed negative effects in humans. They have not irradiated any people just yet..." but now, it seems they make the claim of no negative effects without any radiation. While nice, that doesn't precisely predict no negative effects WITH radiation.

    I'm always a little skeptical when a medical announcement is made by a corporation.

  5. Re:I need a car analogy... by Ihlosi · · Score: 4, Insightful
    Radiation is a good way to cause cancer.

    If you already have cancer, then developing another type of it one or two decades down the road is the least of your worries.

  6. Re:Won't fix DNA damage by fuzzyfuzzyfungus · · Score: 3, Insightful

    Essentially everyone, if they don't get have a heart attack, kiss a bus, or otherwise snuff it early, will eventually succumb to cancer. Assuming this stuff isn't extraordinarily expensive or incredibly nasty in some other way, "survival now, cancer later" would be a good deal for all but the oldest radiation exposure victims.

  7. Re:Just In Time For : by foniksonik · · Score: 5, Insightful

    Why post anonymous troll... don't have any confidence in your assertions? Don't want to have your karma blasted?

    North Korea is like an ugly step-child who will take every opportunity to get back at his more attractive more successful siblings. That kid nobody likes because they always lie about everything and don't take care of themselves, don't try to get along and are generally miserable and make everyone around them miserable.

    Israel is like a self-centered only child who gets all the attention deserved or not and always expects that she gets to go first. The kids she cut in front of long ago despise her but everyone else just takes pity on her as an only child and invite her to their parties to be nice. Sometimes she helps out, if it's in her own interest and then everyone gives her a high five to encourage her to do more for others and be less self-centered...

    Two completely different psychologies that can present themselves in similar ways at times... both are isolated in a way and feel threatened by those around them, so they both feel the need to create and put forward a strong defensive front and both over-react when anyone questions them about it. Otherwise, completely different.

    Now let's get back on topic.

    --
    A fool throws a stone into a well and a thousand sages can not remove it.
  8. Re:72 hours after exposure? by GargamelSpaceman · · Score: 5, Insightful
    No. According to TFA, your DNA is still ripped to shreds, but the drug supresses your cells' suicide mechanism that having 'corrupted data' in the DNA activated. The suicide mechanism helps keep damaged cells from becoming cancerous cells. Instead they become dead cells. In the case of lethal radiation poisoning, this happens to too many cells. Now, your cells already do have mechanisms to repair DNA damage. If something seems out of place, they can often make the right guess as to how to patch things back together. There are corrupt hard drive repair utilities that do this too. But sometimes they make the wrong guess or can't repair the DNA to original condition. That's why you have the suicide mechanism. A cell that has been so severely damaged that the suicide mechanism is activated has an unacceptably high likelihood of being sufficiently damage that it won't be able to be repaired back to 'manufacturers specifications'.

    Rather than take the chance that the repairs that get done will leave the cell cancerous, the cell is programmed to suicide. Another cell will take it's place. But in the case of fatal radiation poisoning, this happens to too many cells at once.

    'Unacceptable risk' that a cell might turn cancerous might be a very low risk indeed, since cancer is fatal 'in the wild'. Most radiation damaged cells might very well be able to repair themselves perfectly if only they didn't suicide. Deactivating the suicide mechanism temporarily gives them time to repair themselves. Once repaired, they no longer want to suicide. However in the case where many cells were radiation damaged, this likely means some cells were repaired incorrectly and will now cause cancer. Maybe this is not as likely as it may seem at first? How well does radiation cause cancer? How exactly does it happen? I've heard that a speck of plutonium inhaled has a 100% chance of causing lung cancer. But that speck is emmitting radiation 24x7 killing and damaging neighboring cells all the time. Is it the nuclear damage to the cells that causes the cancer, or is it the constant healing? Doesn't the body send stem cells to repair damaged areas? Aren't stem cells more cancer prone?

    Maybe in the case of radiation poisoning, the cells are damaged, and if prevented from suiciding, they will be fine. This isn't chronic radiation damage caused by contamination, but rather acute radiation poisoning caused by having rads of radiation shined through you.

    Maybe not. Excessive X-Ray photographs cause cancer don't they? Maybe the irradiated mice and monkeys will be teeming with tumors in short order. Maybe some of them will touch their keepers and pick up some genetic material. Then they will mutate to be more humanlike, including having intelligence, and natural talent at karate. They will go live in the sewers and protect us from evil ninja gangs with their elite Kung Fu skillz.

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  9. Fallout by Quiet_Desperation · · Score: 3, Insightful

    Oh, *please* call it RadAway.

  10. Re:kdawson strikes again by MightyYar · · Score: 5, Insightful

    If you were published in Science, yeah you'd probably get slashdotted.

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    W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  11. Re:YNet isn't the only one who's picked it up.. by Chris+Mattern · · Score: 3, Insightful

    They mean that the substance itself does not cause any observed harm. In the approval of any medicine, the first step is always to demonstrate that the substance is not itself poisonous. Only then do trials progress to determine if it is in fact effective.

  12. American? by Roger+W+Moore · · Score: 3, Insightful

    No they should have just said American. That's what it presumably says on their passport unless they have dual nationality.... and regardless of this it is utterly irrelevant for the story. Can you imagine the uproar had they said "white, male scientists"?

    Not only that but I would imagine that it is somewhat insulting to Americans - are they really that ashamed of being a US citizen that they have to somehow dilute it by mentioning where their family emmigrated from?

  13. Re:YNet isn't the only one who's picked it up.. by JM78 · · Score: 3, Insightful

    I can vouch for the site and newspaper's credibility

    LOL. Well that's fantastic! So tell us oh creditable AC? Who shall now vouch for you?

    --
    I am Jack's smirking revenge.
  14. This is actually bad news... by wealthychef · · Score: 3, Insightful

    It will make governments less averse to using nuclear weapons.

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    Currently hooked on AMP
  15. And better still, increases acceptance of N power by SuperKendall · · Score: 4, Insightful

    Consider this - with an effective "cure" for radiation, it ceases to become a bogeyman and people will be a LOT more comfortable with clean, efficient nuclear power stations nearby. It takes out a large leg from the alarmists that try to stop them from being built.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley