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Fully Functional Bioengineered Tooth Grown In a Mouse
A couple of weeks back the Wall Street Journal reported on the first organ grown in vivo from stem cells — a tooth in the mouth of a mouse. Reader cdrpsab spotted the news on the MedGadget blog; the research had been reported earlier in the PNAS. From the WSJ: "The researchers at the Tokyo University of Science created a set of cells that contained genetic instructions to build a tooth, and then implanted this 'tooth germ' into the mouse's empty tooth socket. The tooth grew out of the socket and through the gums, as a natural tooth would. Once the engineered tooth matured, after 11 weeks, it had a similar shape, hardness and response to pain or stress as a natural tooth, and worked equally well for chewing. The researchers suggested that using similar techniques in humans could restore function to patients with organ failure."
Yours sincerely,
Dean, on behalf of millions of Type I diabetics
P.S. I *love* hearing about this stuff. The potential for helping millions is incredible.
The subject who is truly loyal to the Chief Magistrate will neither advise nor submit to arbitrary measures (Junius)
Honestly, I don't think that calling a tooth an organ is very much of a stretch. Teeth have their own blood vessels and nerves, and consist of a large proportion of living tissue. This little blurb provides what I think is a convincing, if hardly exhaustive, argument that teeth are organs.
It wouldn't be bad if humans were able to grow new teeth every thirty to forty years or so.
Teeth wear down, cracks and so on so it would sure not be bad.
If builders built buildings the way programmers wrote programs, then the first woodpecker would destroy civilization.
Found It
To anybody wishing for this: be sure to specify that the teeth grow in the correct place. The alternative is rather gross.