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Seasonal Flu Shots Double Risk of Getting Swine Flu, Says New Study
krou writes "A Canadian study currently under peer review apparently suggests that individuals given seasonal flu shots are twice as likely to get swine flu. The 'perplexing' study has thrown influenza health plans into disarray, with Quebec, Alberta, Saskatchewan, Ontario and Nova Scotia all suspending seasonal flu shots for anyone under 65 years of age. The study appears to be confined to Canada; the US, Britain, and Australia have not reported the same problem, so some are suggesting that the research has 'study bias.' However, the research appears to be 'solid' according to Dr. Ethan Rubinstein, head of adult infectious diseases at the University of Manitoba. 'There are a large number of authors, all of them excellent and credible researchers. And the sample size is very large — 12 or 13 million people taken from the central reporting systems in three provinces.''
IF you have health problem, or a weak immunitary system, then you are likely to have had flu shots in the past, AND you are likely to catch swine flu now that a shot for it does not exist yet. So nothing particularly stunning here.
My first program:
Hell Segmentation fault
Don't get vaccinated for multiple strains that are more deadly because it makes you twice as likely to catch only one strain?
Oh, and this story made me think of this comic. Applies perfectly here.
This is not necessarily surprising or a new idea. A researcher at Rice University (Michael Deem, whom I have heard speak on this) studies the genetic basis for the vaccine and the resulting efficacy in any given year and there are MANY years in which getting a flu vaccine the previous year will actually increase your chances of getting the flu the next, or make it worse. You can find an interesting calculator here: http://www.mwdeem.rice.edu/pepitope/, where there is also a link to his most important paper on it at the bottom (no registration req.). Here is an excerpt:
Vaccine efficacy can even be negative, however, due to original antigenic sin [7-9], the tendency for antibodies produced in response to exposure to infl uenza vaccine antigens to suppress the creation of new, different antibodies in response to exposure to new versions of the infl uenza virus. The efficacy of the annual in fluenza vaccine, and whether original antigenic sin may occur, depends sensitively on how similar the vaccine and circulating viral strains are. Current state of the art measures of antigenic distance are based on ferret antisera hemagglutinin inhibition assays [10-12], and these distances are assumed to correlate well with vaccine efficacies in humans. However, to our knowledge no such good correlation has ever been shown for an experimental or theoretical measure of antigenic distance.
Ever since I heard this talk, and learned that the flu vaccine is actually a random guess each year, I don't bother with it. I'm young, strong, and tough and very very unlikely to die, I figure.
"sometimes he felt that his whole life was a dream, and he wondered whose it was and whether they were enjoying it."
1. Look up Rhinovirus and Influenza.
2. Notice that they are not the same thing.