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Scientists Write Memories Directly Into Fly Brains

TheClockworkSoul writes "Researchers at the University of Oxford have devised a way to write memories onto the brains of flies, revealing which brain cells are involved in making bad memories. The researchers said that in flies, just 12 brain cells were responsible for what is known as 'associative learning.' They modified these neurons by adding receptors for ATP, so that the cells activate in the presence of the chemical, but since ATP isn't usually found floating around a fly's brain, the flies generally behave just like any other fly. Most interestingly, however, is that the scientists then injected ATP into the flies' brains, in a form that was locked inside a light-sensitive chemical cage. When they shined a laser on the fly brains, the ATP was released, and the 'associative learning' cells were activated. The laser flash was paired with an odor, effectively giving the fly a memory of a bad experience with the odor that it never actually had, such that it then avoided the odor in later experiments. The researchers describe their findings in the journal Cell."

3 of 137 comments (clear)

  1. Re:Wait a second... by TheClockworkSoul · · Score: 5, Insightful

    Well, just a thought, but wouldn't one such possible control be shining the laser on flies without ATP receptors?

  2. Re:Bad odor by dov_0 · · Score: 5, Insightful

    If only they could program them to avoid the smell of BBQ meat...

    --
    sudo mount --milk --sugar /cup/tea /mouth /etc/init.d/relax start
  3. Re:Why? by fuzzyfuzzyfungus · · Score: 4, Insightful

    Two basic lines of response:

    A) Sure. Loads of morally correct applications. There are plenty of situations where the mere existence of a given memory is the point of the exercise. Many forms of instruction/training, for instance. If the memory of having read the manual is false; but the contents of the manual you falsely remember having read are true, you win. You'd need the subject's consent; but it isn't at all hard to imagine plenty of situations where people would be delighted to knowingly have various useful memories implanted.

    B)An experimental result like this is quite far from application, well within the realm of basic research into memory functions. Understanding memory function, while it would have both positive and negative potential, is arguably a net positive. Right now, if I want to implant an unpleasant memory, or fuck with your sense of reality, or otherwise do nasty things to you, I don't really need a sophisticated understanding of memory. A water bottle and your T-shirt and no sense of decency will do well enough. If, however, I want to improve education, or understand why certain psychiatric disorders include serious memory problems, or treat brain injuries, or what have you, knowledge of the neurology of memory systems is necessary.

    There could certainly be, at least in principle, scientific/technological developments that are just plain bad news; but I don't think that this is one of them. Virtually all the potential downsides can be achieved(or at least closely approximated) by far lower tech means, while many of the potential upsides are otherwise out of reach.