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The Medical Benefits of Carbon Monoxide

tugfoigel writes with this excerpt from the Boston Globe: "For more than a century, carbon monoxide has been known as a deadly toxin. In an 1839 story, Edgar Allan Poe wrote of 'miraculous lustre of the eye' and 'nervous agitation' in what some believe are descriptions of carbon monoxide poisoning, and today, cigarette cartons warn of its health dangers. But a growing body of research, much of it by local scientists, is revealing a paradox: the gas often called a silent killer could also be a medical treatment. It seems like a radical contradiction, but animal studies show that in small, extremely controlled doses the gas has benefits in everything from infections to organ transplantation."

21 of 177 comments (clear)

  1. I've seen this story before! by MillionthMonkey · · Score: 3, Funny

    NO!

    1. Re:I've seen this story before! by Anonymous Coward · · Score: 5, Funny

      NO is nitric oxide, not carbon monoxide.

  2. Gee whiz! by mcsnee · · Score: 5, Insightful

    Something that is bad for us in high doses may be beneficial in low doses?! Next they'll be telling us that exposure to radiation and toxins can help cure cancer, or that the same stuff that rusts away unprotected steel and iron is actually necessary for animal life!

    1. Re:Gee whiz! by wjh31 · · Score: 3, Funny

      See, homeopathy works.

    2. Re:Gee whiz! by xTantrum · · Score: 5, Insightful
      seriously people this isn't that "paradoxical". Chem 101. As (arsenic) is also deadly but its also an essential biological trace element. Its about moderation.

      Sometimes i can't believe i still surf this place.

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    3. Re:Gee whiz! by Anonymous Coward · · Score: 5, Funny

      I can't believe you still use the word 'surf'.

    4. Re:Gee whiz! by Thinboy00 · · Score: 5, Informative

      Actually, Homeopathy often dilutes the "dose" until it is improbable that there is a single molecule of the original substance remaining

      --
      $ make available
    5. Re:Gee whiz! by Anonymous Coward · · Score: 4, Funny

      As (arsenic) is also deadly but its also an essential biological trace element. Its about moderation.

      That may be true, but there are clearly some very dangerous chemicals like nitroglycerin that couldn't possibly have any medical uses.

    6. Re:Gee whiz! by jbengt · · Score: 5, Funny

      Homeopathy is wrong for two reasons--one, it postulates that chemicals/herbs/medicines that cause a symptom will cure that symptom, . . .

      Well, the same ethanol that caused my morning headache seems to have cured it.

    7. Re:Gee whiz! by The+Archon+V2.0 · · Score: 4, Funny

      (Not an industry shill, just a pragmatist posting anonymously to avoid harassment from anti-DHMO zealots).

      You'd better post anonymously. Crazies like you just love it when people can get DHMO without any sort of oversight. You want them to think they can't live without it! It's bloody dangerous! That crap gets in your lungs and you DIE!

    8. Re:Gee whiz! by Gabrill · · Score: 4, Insightful

      Because multicellular organisms like homo sapiens can survive a poison that virii or bacteria cannot. Hasn't that been the basis of a great deal of medicine for over a century now?

      --
      Always going forward, 'cause we can't find reverse.
  3. not a paradox by fermion · · Score: 4, Insightful

    Almost anything is lethal in large doses, and many things are fatal in even small doses. Those same things are often of some benefit in very small doses. For instance, Botulinum toxin. We use small and weakened versions of virus to immunize ourselves. Most medicines can kill children who ingest a moderate overdose. A little alcohol can be antiseptic, which is why many places in the world used to drink with their food, but too much alcohol is lethal.

    --
    "She's a scientist and a lesbian. She's not going to let it slide." Orphan Black
  4. All things are poison... by notdotcom.com · · Score: 5, Informative

    Paracelsus, sometimes called the father of toxicology, wrote:

            German: Alle Ding' sind Gift, und nichts ohn' Gift; allein die Dosis macht, daß ein Ding kein Gift ist.
            "All things are poison and nothing is without poison, only the dose permits something not to be poisonous."

    That is to say, substances often considered toxic can be benign or beneficial in small doses, and conversely an ordinarily benign substance can be deadly if over-consumed. Even water can be deadly if overconsumed.

    (Ripped right from Wikipedia [ http://en.wikipedia.org/wiki/Paracelsus ] )

    So, 500 years ago, this would have been news?

    --
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  5. You also get synergistic benefit if you... by jeffb+(2.718) · · Score: 3, Funny

    ...coadminister with tetraethyl lead.

  6. Small enough or a precise amount? by gmuslera · · Score: 3, Funny

    Would not be the only beneficial peak around.

  7. Re:Digitalis, eh? by gyrogeerloose · · Score: 5, Funny

    Take iron, for instance. It's an essential trace mineral but drop an anvil on your foot and you're in a world of hurt...

    --
    This ain't rocket surgery.
  8. Most all posions by nurb432 · · Score: 4, Insightful

    Have their medicinal values. Most medicines become poisonous at a certain level too, so there is some symmetry to it all.

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    ---- Booth was a patriot ----
  9. Re:Cigarettes by treat · · Score: 4, Informative

    Maybe not cigarettes, but tobacco sure. Heroin also has huge medical benefits, but we can't touch that, can we?

    In much of the world, heroin is recognized as being a safe and effective pain killer. It is used regularly in hospitals in the UK.

    The reason heroin is an effective recreational drug is due to its safety compared to other opiates.

    The situation is similar (although much more extreme) with methamphetamine. Enough caffeine to keep you awake for a week would have a high chance of killing you outright.

    Considering the low cost of making heroin from morphine, the use of morphine instead is essentially a deliberate waste in order to satisfy political considerations.

  10. Hrmm by sjames · · Score: 3, Insightful

    From TFA:

    But given the deeply entrenched fear of carbon monoxide as a toxin, he said it is unlikely that the gas would be directly given as a therapy to many people. Instead, research into the mechanism by which carbon monoxide works could allow scientists to design a drug that could act in the same way.

    REALLY? Because CO has a scary reputation we'd rather give patients a new expensive patented drug that we think works just like CO rather than just give them a well controlled dose of a well understood, inexpensive, and easily available gas?

    No wonder nobody can afford health care.

  11. How is that a contradiction? by nedlohs · · Score: 3, Informative

    Radiation is generally bad for you, but we use it as a medical treatment.

    Pick your favorite medical prescription, now eat 10 lbs of it. Oh look it's bad for you.

  12. In the 60's it would keep the kids quiet. by kurt555gs · · Score: 3, Informative

    A lot of you here are to young to remember the big boat station wagons that parents would pile full of stuff and kids and head off to places like Yellowstone and the like. Many of these had rear facing seats and power rear windows. The only problem was that if you let the window down a little, the car exhaust would be sucked into the car, especially near the rear facing seats where the kids were. Now many would think this is a problem, but parents of that day, after having to listen to the little brats giggling, and yelling would crack that rear window and let a little CO in to quiet the kids down. It worked, they went to sleep, and the only drawback was a few points off the ACT scores later in High School.

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