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Placebo Effect Caught In the Act In Spinal Nerves
SerpensV passes along the news that German scientists have found direct evidence that the spinal cord is involved in the placebo effect (whose diminishing over time we discussed a bit earlier). "The researchers who made the discovery scanned the spinal cords of volunteers while applying painful heat to one arm. Then they rubbed a cream onto the arm and told the volunteers that it contained a painkiller, but in fact it had no active ingredient. Even so, the cream made spinal-cord neural activity linked to pain vanish. 'This type of mechanism has been envisioned for over 40 years for placebo analgesia,' says Donald Price, a neuroscientist at the University of Florida in Gainesville, who was not involved in the new study. 'This study provides the most direct test of this mechanism to date.'"
Would be interesting to see if similar effects could be observed regards acupuncture which is rated to be in the realm of placebo by 'old school' medicine.
CC.
TaijiQuan (Huang, 5 loosenings)
I have chronic headache and have been a subject in studies. It is well-known that anticipation is an observable component to pain notification and response. To an almost hilarious extent, pain is like gravity in cartoons: if you don't believe it exists, you're less likely to experience it.
captcha: scratchy (they fight...)
> Even so, the cream made spinal-cord neural activity linked to pain vanish.
The cream did no such thing, the people's minds did this. It's quite unsurprising that as the brain processes pain (which is just information about damage to tissue), that the brain can also switch it (the processing, i.e. feeling) off.
I can do this whenever I want. First time I did this when I was 12 or so, and for the umpteenth time the lid of the kettle to boil water for tea fell off, and I burnt my hand. Painful and annoying. I said to myself: Enough, no more pain! And gone it was. Not really anything special I believe, see e.g. fakirs.
Of course the 'placebo effect' is more than just turning off pain, it's also about getting better without medicine, i.e. making your body do things to repair itself. This I also do consciously (i.e. I tell myself that my immune system should work harder to kill the 'intruders' :)) and may be the reason why I'm almost never ill, and when I am, I recover very quickly (I never go to a doctor).
Reminds me of a Married with children episode btw.:
[ Al ] I feel strong!
{ Peggy says something }
[ Al ] I feel weak...
(paraphrasing).
I don't quite understand your point. We already know that acupuncture works. We also know why it works: it works 100% through the placebo effect. This newly discovered mechanism may or may not apply to acupuncture, but it doesn't really matter; we already know that acupuncture has no specific activity for the condition that is being treated. This new discovery does not change this simple fact, and thus does not require us to re-analize acupuncture.
The results would be exactly the same as earlier tests.
Yes, that's the point. The study is showing physiological effects of patient expectation. Patient expectation is based on past experience, cultural beliefs, and whatever the doctor (or any other person in authority, for that matter) tells you, even if the treatment is just an inert cream or a sugar pill. This study is just confirmation that when a patient claims to feel less pain, there is actual nervous system activity to support this perception.
The perception of pain, and indeed all neurological processes, are not incorporeal and can be shown to have actual physical mechanisms.
Three hundred and fifty years after Willis et al showed that the brain was the physical seat of perception, it is incredible that the mythology of "mind over matter" is even coherent to anyone anymore: mind is matter. Why anyone believes otherwise is a mystery.
Yet we still see people in response to this article saying "the placebo effect isn't an effect", as if the physiological response that results in an altered state of belief isn't real because they believe for some reason that psychological states aren't real. The placebo effect is a perfectly ordinary physiological effect, as all psychological effects are. That we can access our physiology via words, ideas and beliefs is no great suprise, since those words, ideas as beliefs are generated by our physiology as well.
I guess maybe most people are simply too dim to understand the concept of a system that can act as both a creator/transmitter of beliefs and a reciever/responder to beliefs, although given their own hands, for example, act both as input and output devices makes that a little hard to credit.
It would be extremely interesting to know exactly where the failure of reasoning occurs in people who believe that mind and matter are independent and unrelated things, and the mind is somehow "less real" than the matter that constitutes it.
Blasphemy is a human right. Blasphemophobia kills.
No active ingredient? They did apply a cream. If you've had painful heat applied to your arm, rubbing butter on it will make it feel better; lidocaine would feel MORE better*, but this isn't a sugar pill.
* "Me fail English? That's unpossible!"
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$x=~y+ -xz+\0-Tx+;print$_^chop$me for split'',$x;