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Re-Engineering the Immune System

destinyland notes a microbiology professor describing "Immunity on Demand" (or "Immunity 2.0") and wonders whether we could genetically engineer all the antibodies we need. "...there's a good chance this system, or something like it, will actually be in place within decades. Caltech scientists have already engineered stem cells into B cells that produce HIV-fighting antibodies — and an NIH researcher engineered T cells that recognize tumors which has already had promising clinical trials again skin cancer. Our best hope may be to cut out the middleman. Rather than merely hoping that the vaccine will indirectly lead to the antibody an individual needs, imagine if we could genetically engineer these antibodies and make them available as needed?"

2 of 175 comments (clear)

  1. Re:I was under the impression by eparker05 · · Score: 5, Interesting

    For most diseases the antibodies are easier to see because they are more widespread. It only takes a few virally infected cells to set off a massive immune response. The difficulty in engineering an antibody is the same difficulty as engineering any protein. Our knowledge of protein folding is still in it's infancy. So far, we have used evolutionary methods to find new antibodies. Perhaps someday we will be able to build them from the ground up, but not now.

  2. Re:Hey, awesome... by osu-neko · · Score: 5, Interesting

    Lets cure all natural causes of death through the miracle of modern science. Then starve to death as the world becomes grossly overpopulated.

    Problem: All evidence suggests the opposite. Eliminate all the most egregious morality concerns from a population, and they stop reproducing like rabbits. In the healthiest parts of the first word, population growth is going negative.

    --
    "Convictions are more dangerous enemies of truth than lies."