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Chemical Cocktail Can Keep a Heart Viable 10 Days, Outside the Body

nj_peeps writes "Harvard professor Hemant Thatte has developed a cocktail of 21 chemical compounds that he calls Somah, derived from the Sanskrit for 'ambrosia of rejuvenation.' Using Somah, Thatte and his team have accomplished some amazing feats with pig hearts. They can keep the organ viable for transplant up to 10 days after harvest — far longer than the four-hour limit seen in hospitals today. Not only that, but using low temperatures and Somah, they were able to take a pig heart that was removed post mortem and get it to beat 24 hours later in the lab."

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  1. Here's what's in it by Yergle143 · · Score: 5, Informative

    From the paper it's a modification of something called GALA solution.
    Compenent mmol/L g/L
    Distilled water, L 1.00
    Calcium chloride 1.30 0.191
    Potassium chloride 7.00 0.522
    Potassium phosphate (monobasic) 0.44 0.060
    Magnesium chloride (hexahydrate) 0.50 0.101
    Magnesium sulfate (heptahydrate) 0.50 0.123
    Sodium chloride 125.00 7.31
    Sodium bicarbonate 5.00 0.420
    Sodium phosphate (dibasic; heptahydrate) 0.19 0.05
    d-Glucose 11.00 1.982
    Glutathione (reduced) 1.50 0.461
    Ascorbic acid 1.00 0.176
    l-Arginine 5.00 1.073
    l-Citrulline malate 1.00 0.175
    Adenosine 2.00 0.534
    Creatine orotate 0.50 0.274
    Creatine monohydrate 2.00 0.298
    l-Carnosine 10.00 2.26
    l-Carnitine 10.00 2.00
    Dichloroacetate 0.50 0.075
    Insulin 10 mg/mL, mL/L 1.00
    pH is adjusted to 7.5 with sodium bicarbonate or Tris-hydroxymethyl aminomethane at desired temperature.

    Bunch of salts.
    These aren't complex proteinaceous molecules. I am interested in the presence of dichloroacetate because that was the anti-cancer molecule reported
    by slashdot just yesterday.
    http://science.slashdot.org/article.pl?sid=10/05/13/2117203

    Now all you hackers planning to preserve human hearts don't you use this formula without citing the good Doctor Thatte.
    Please mod me up for my chemical knowhow