Slashdot Mirror


Researchers Restore Youthful Memory In Aging Mice

An anonymous reader writes "German neuroscientists made a breakthrough in 'age-related cognitive decline', a common condition that often begins in one's late 40s (especially declarative memory — the ability to recall facts and experiences). Their new study identifies a genetic 'switch' for the cluster of learning and memory genes that cause memory impairment in aging mice. By injecting an enzyme, the team 'flipped' the switch to its on position for older mice, giving them the memory and learning performance they'd enjoyed when they were young. Now the team ultimately hopes to recover seemingly lost long-term memory in human patients." The video, which explains the gene flipping mechanism, is worth a watch (2:18).

4 of 145 comments (clear)

  1. 42 by Jhon · · Score: 4, Interesting

    That's my age. I do notice tt takes just a wee bit more effort to cram more stuff in my head than it used to. Other than that, I still enjoy my ability to recall ridicules bits of obscure minutia that when viewed in total aren't enough to get me a good job, but are just enough to be annoying.

    Seriously, though. My ability to commit stuff to memory and recall it *IS* one of my marketable skills. And anything that can help prolong the decline is welcome news.

  2. Re:This research is phenomal! by tsotha · · Score: 4, Interesting

    It's not clear to me a treatment for normal cognitive decline would necessarily be effective for Alzheimer's.

  3. I'm in my late 40s... by IANAAC · · Score: 3, Interesting
    and while I do notice it takes a bit more effort to learn something new, once I do I can retain it without problems, provided I use the knowledge.

    Languages have always interested me (it's what I do for a living these days), and every couple years I try to learn the basics of another language. I find that as long as I exercise the newly learned skill/material, I'm OK (such as reading newspapers in the other language, listening to broadcasts in that language, and finally speaking the language whenever I get the chance. I would imagine I'm using a different part of the brain for these activities, though.

    I'm certainly no expert, nor do I claim to know anything of how the mind works for that matter, but I can't help but think that actually using skills learned later in life helps.

  4. This can only have positive results. by Minwee · · Score: 4, Interesting

    Nov 21 - I did a dumb thing today I forgot I wasnt in Miss Kinnians class at the adult center any more like I use to be. I went in and sat down in my old seat in the back of the room and she lookd at me funny and she said Charlie where have you been. So I said hello Miss Kinnian Im redy for my lessen today only I lossed the book we was using.