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Hair Growth Signal Dictated By Fat Cells

RogerRoast writes "According to an article published in the journal Cell, molecular signals from fat cell (adipocyte) precursors under the skin are necessary to spur hair growth in mice. Yale researchers report in the paper that these cells produce molecules called PDGF (platelet derived growth factors), which are necessary to produce hair growth. The discovery of the source of signals that trigger hair growth may lead to new treatments for baldness. The trick is in getting adipocyte precursors under the skin to talk to stem cells at the base of the hair follicles."

8 of 146 comments (clear)

  1. Re:So this means... by Samantha+Wright · · Score: 5, Informative

    That's a negative, Red Leader. While you get more adipocytes when you gain weight, you keep them after you lose it. Get back on the treadmill!

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  2. Re:Idiocracy by Samantha+Wright · · Score: 3, Interesting

    Damn. Beat me to it.

    On the plus side, most of the research into prolonging erections has already been done. Apparently there's a sweet spot for ideal duration. So at least we don't have to worry about that.

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  3. IN MICE by snowgirl · · Score: 4, Informative

    This finding has been made IN MICE. Now, I'm not usually one to suggest that just because an effect is demonstrated in a lab animal that it won't apply to humans, but hey, saccharine only caused bladder cancer in lab rats because they have a different urinary tract, and they were retaining it in a way that would never happen in humans.

    Now, the disclaimer being made, women have a larger dispersion of fat about the whole body, and while they have more vellus hair then men, vellus hair is hardly noticeable, and in fact, "balding" is typically a result of the hair on one's head turning into vellus hair. So, making humans grow more vellus hair isn't really going to solve anything.

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  4. Re:Idiocracy by Chrisq · · Score: 5, Insightful

    While you're at it, imagine there's no more wars, no more poverty, and endless youth.

    That's just as realistic as trying to tell scientists what kind of research they are interested in.

    Somehow I think it is more a case of "which treatments will get funding" than "what scientists are interested in".

  5. Re:So this means... by c0lo · · Score: 4, Informative

    That's a negative, Red Leader. While you get more adipocytes when you gain weight, you keep them after you lose it. Get back on the treadmill!

    Mod parent +Informative, because... ...shit, I start pulling my hair over this!!!

    The horror: after you gained them, you need to stay on thread mill for years to get them back to the previous level (increase them exponentially, lose the linearly).

    If excess weight is gained as an adult, fat cells increase in size about fourfold before dividing and increasing the absolute number of fat cells present.
    ...
    Approximately 10% of fat cells are renewed annually at all adult ages and levels of body mass index.

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  6. Re:I started to lose my hair when I was 17... by blackest_k · · Score: 3, Insightful

    I wasn't losing my hair at 17 but I am now so rather than prolong the agony I just shave it every day or so.

    Hair is all about vanity and insecurity. You want to look attractive but to be honest confidence is more attractive than any hair style. So grasp the nettle shave off all or most of it and get on with living your life. The sooner you do it the sooner your skin tone will even out and you know women love a confident self assured man.

    The guy worried about his hair loss isn't that man.
    For women hair loss is probably harder to handle and pretty common but again do it bald women have character and attitude both sexy attributes.

    There is nothing wrong with standing out from the crowd in fact it is an asset.

    There is no cure for baldness just ways of looking a little less bald even hair transplants don't work they look like somebody who has had a hair transplant.

    so feck it go get the razor and get on with your life.

  7. The OP is an example of Idiocracy by the_raptor · · Score: 3, Insightful

    Imagine if all this research went into AIDS or malaria.

    Nothing of significance cause I guarantee you that AIDS and malaria research receives more money then one team investigating aspects of how our largest organ works.

    Also accusing scientists of not doing "noble enough" research while screwing around on Slashdot is like a fat guy complaining about the form of a sprinter.

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  8. Re:Idiocracy by Niedi · · Score: 4, Informative

    pubmed results for
    "hair loss": 2.554 research papers
    baldness: 14.919 research papers
    "erectile dysfunction": 16.292 research papers
    malaria: 59.503 research papers
    HIV: 229.598 research papers

    Just a rough approximation, but it seems there IS research on malaria and HIV going on after all...