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DNA May Carry a Memory of Your Living Conditions From Childhood
An anonymous reader writes "Canadian and British scientists have found that how rich your family was when you were a kid — as judged by wealth, housing conditions and occupation of parents — has a huge impact on your current DNA. 'This is the first time we've been able to make the link between the economics of early life and the biochemistry of DNA,' says Moshe Szyf, professor of pharmacology at McGill University. The study did not show whether the DNA changes identified are passed on to offspring, but if so, repeat cycles of poverty could be putting poor children at a serious disadvantage for heart disease, diabetes and lung disorders."
The changes in DNA are due to methylation of the DNA, not changes in sequence. This can lead to more or less of a given gene being expressed, but won't lead to any actual changes in the genes.
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"but if so, repeat cycles of poverty could be putting poor children at a serious disadvantage for heart disease, diabetes and lung disorders."
What is this based on? Perhaps extra robustness is built in for exactly the reason that you may run more risk? So having poor parents may actually give you an advantage...
Everyone can't be rich, but with a little work, everyone could not be poor.
"Who is the Journal of Quantum Physics going to believe?" --Stephen Hawking
> There are always going to be 'haves' and 'have nots' in this world...that's the way of nature.
I think you're confusing nature with modern society.
Yes, but changes in fundamental sequence aren't the only way genes 'change'. Changes in expression constitute almost all of the biological changes that affect to an organism during its lifetime, as opposed to merely affecting its offspring; it's only because of expression changes that you ever go from a fetus to an adult (or from a fetus to a slightly larger fetus, for that matter).
I mean, presumably you understand this, unless you're able to talk about methylation solely from reading the article, but I don't want anyone to get the impression that 'only' changing the way DNA is expressed is a small feat.
Expression is *everything*. Almost nothing can be accomplished in any eukaryotic organism without deliberate changes in expression like this; basal transcription (the rate at which your genes are used entirely because the right parts randomly came together with nothing else - like methylation - helping or preventing them) accomplishes almost nothing.
The human genome is a lot like a computer in that way: almost nothing happens without something specifically telling it to work, and these guys just discovered a whole damn code library.
Sounds a lot like a Nova program I saw some time ago. It titled 'Ghost in your genes'. It talked about how epigenetics control how your genes are expressed and they had noticed some inherited traits based on whether the ancestors were poor, starving, folk or not.
With appropriate measures, the minimum standard of living can be made good enough to not result in a permanent health effect.
The haves will always write off disparity of wealth as "oh well, just one of those things" right up until the poor start camping in their front yard.
Fail.
Poverty is the state of one who lacks a certain amount of material possessions Absolute poverty or destitution is inability to afford basic human needs, which commonly includes clean and fresh water, nutrition, health care, education, clothing and shelter. About 1.7 billion people are estimated to live in absolute poverty today. Relative poverty refers to lacking a usual or socially acceptable level of resources or income as compared with others within a society or country.
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