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Gut Bacteria Can Control Diabetes

Shipud writes "Insulin resistance is the harbinger of metabolic syndrome. Insulin resistance is when the body cannot use insulin effectively. As a result, blood sugar and fat levels rise. Therein lies the path to morbid obesity, diabetes, stroke, and heart problems. A group of Brazilian researchers have taken a strain of mice normally known to be immune to insulin resistance, and made them insulin resistant (pre-diabetic) by changing their gut bacteria. They then gave the mice antibiotics, and by changing their gut bacteria again, reversed the process, curing them of the disease. Their research shows just how influential the bacteria living in our gut can be on our health."

6 of 271 comments (clear)

  1. Re:so by dintech · · Score: 5, Informative

    Actually, you can transplant human gut bacteria to treat disease. It's called Fecal Bacteriotherapy. It's a procedure carried out under the supervision of a doctor where you put a donor's shit up your ass. Unappealing certainly, but at least it's not 2girls1cup style.

  2. Re:so by Attila+Dimedici · · Score: 5, Informative

    No, what they discovered is actually a flaw in existing research into insulin resistance. To summarize the linked article: There is a strain of mice that did not develop insulin resistance from any of the usual procedures used to induce insulin resistance in mice. This particular group of researchers noticed that these diabetes resistant mice were typically housed in isolation from normal mouse micro-organisms. These researchers housed a group of these mice in "conventional facilities" (as opposed to "germ-free" facilities, which was normal) where they were exposed to various bacteria. These mice then developed insulin resistance. When the gut bacteria from these mice were transplanted into other mice, those mice, also, developed the symptoms of insulin resistance. Finally, if these mice were given broad spectrum antibiotics (presumably killing off the microbiota that had developed in their guts) they lost their insulin resistance.
    In summation, what they discovered is that the micro-organisms that live in your intestines play a role in whether or not you develop Type 2 diabetes.

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    The truth is that all men having power ought to be mistrusted. James Madison
  3. Re:Or you could just not be overweight by Wonko+the+Sane · · Score: 5, Informative

    Part of the problem is that so many people have been taught that "eating well" means avoiding saturated fat and eating lots of grains and vegetable oil, despite the evidence that such a diet has the exact opposite effect of what is claimed. Once you figure out that eating well means almost the complete opposite of what the government-sponsored experts have been telling us for the last 30 years it becomes very easy to reverse the process.

  4. Re:so by PCM2 · · Score: 4, Informative

    Another fun fact: Guess how gut flora are "seeded" in humans? Hint: It's more effective with natural childbirth.

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    Breakfast served all day!
  5. Re:Or you could just not be overweight by Wonko+the+Sane · · Score: 5, Informative

    I lost 50 lbs by eliminating sugar, starches and grains (and byproducts) and replacing those with saturated fats, green vegetables and meat without even bothering to think about calories and without spending nearly every waking moment exercising. The primal/paleo diets work for a lot of people, far more than are able to make a low-calorie, low-fat diet work for any substantial period of time.

  6. Re:so by asoukup · · Score: 5, Informative

    Here's a link via scientific american
    http://io9.com/5872507/the-appendix-might-actually-be-the-bodys-bacteria-storehouse

    Google "appendix gut bacteria" and there are loads of articles even from 3-4 years back.