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Brain Scan Can Detect Autism In Infants

kkleiner writes "A new study shows that brain scans can detect autism in children as young as 6 months old. Researchers at University of North Carolina's Institute for Developmental Disabilities imaged the brains of 92 children who were at high risk for autism. Scans were performed when the children were 6 months, 1-year, and 2-years old. At 2 years, the age when children are typically diagnosed, 30 percent of the children were found to have autism. The researchers then compared the brain images of the autistic children with the others. They saw differences in the brain's white matter, the axon-laden pathways that transmit electrical signals to distant parts of the brain. Of the 15 pathways analyzed, 12 were significantly different between autistic and non-autistic children."

7 of 166 comments (clear)

  1. This is one of those things... by ackthpt · · Score: 5, Insightful

    It's like a smoke detector which is telling you your house is already on fire, but can do nothing about putting it out or preventing it from happening.

    Might be useful in some way for consulting with parents, but a knife-edge decision there, to decide whether to tell people their child might develop Autism, with the possibility you culd be wrong. While it is interesting information the practice side of how to use it raises some questions.

    --

    A feeling of having made the same mistake before: Deja Foobar
    1. Re:This is one of those things... by ianbean · · Score: 5, Informative

      1) The original research article is open access so you can take a look for yourself. The differences were statistically significant between the two groups (ASD-positive versus -negative) but there isn't enough data to estimate a sensitivity or specificity for using this as a test. 2) It could be a diagnostic test. In theory that would allow potential treatments to begin before the behavioral aspects of ASD manifest (which is around 2yo correct?)

    2. Re:This is one of those things... by slew · · Score: 5, Interesting

      FWIW, this seems to be just the latest in research that has been coming out in the last few years that seem to add to the evidence that autism onset is really early or preterm.

      For instance, that this paper that came out in 2005 attempted to more systematically document the early signs of autism by using a longitudinal study which comparing a set of high risk infants (who had an older sibling diagnosed w/ some ASD), with a control set at 6 months, 12 months, and 24 months.

      Of course today, autism is defined in terms of behavior. The key is the origin or eitology of autism. Is this odd brain scan an indicator of the origin, or is it something else and this is merely correlated. Nobody knows.

      However, we do seem to have strong indication of certain specific chromosomal problems that can lead to autistic behavior: FragileX, Rett Syndrome, and Tuberous Sclerosis. Fragile X and Rett's are X chromosome related. This is suspiciously related to the observation that incidence of ASD are higher in boys and boys only have 1 "X" chromosome. TS is not X related, but can cause calcium deposits to develop in the brain or in some cases tuber-like growths in the brain (as special case, since tuber-like growths occur all over the body w/ this condition).

      Because of the accumulated research, many people speculate that there are actually many pathways to autistic behaviour. You might even think of autism as a symptom of many diseases and conditions (like a cough is a symptom of many diseases), so many experts are not optimistic that will be a "cure" for autism, but perhaps in the future there will be a way in some situations to blunt the symptoms early enough to avoid many of the problems in many of the common cases.

      Reality is often much more complicated that the headlines.

  2. Re:Brain scan introduces radiation into the brain by jamesh · · Score: 5, Funny

    The technique is essentially harmless.

    Except that 30% of those scanned in the study now have autism... coincidence? ;)

  3. Re:Brain scan introduces radiation into the brain by Tanktalus · · Score: 5, Funny

    The technique is essentially harmless.

    Except that 30% of those scanned in the study now have autism... coincidence? ;)

    I bet most of that 30% also were exposed to that super-dangerous Dihydrogen Monoxide, too. That's where I'd put my money. After all, some kids have autism without ever being scanned, and most of them were probably exposed to DHMO. Parents give that stuff to their kids like it was water, without ever realising how dangerous it is!

    I'd go on, but I have to go take my kids to their swimming class.

  4. Re:Not early enough. by budgenator · · Score: 5, Insightful

    Lack of empathy that your displaying is also a frequent symptom of autism.

    --
    Apocalypse Cancelled, Sorry, No Ticket Refunds
  5. Re:Not early enough. by Ethanol-fueled · · Score: 5, Interesting

    Horseshit detector clicking rapidly. You may gain credibility, however, by describing to us your socioeconomic background and (approximate) age.

    We're not talking about Aspergers, the highest-functioning and probably most abused disability diagnosis aside of ADD (shit, I feel ADD right now. Can I get some Adderall and have an extra 4 hours to take that test? It's the new affirmative action! )

    We're discussing pure autism, and for somebody who claims to have a remarkably high IQ, you're pretty ignorant and have no personality or style. You reek of a pseudo-intellectual who can use 4-syllable words. But you're not a special snowflake, and your disability and/or parents' money will get you into that school of choice.

    -- Ethanol-fueled